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T80686γ-AA peptide P6;化合物 γ-AA peptide P6γ-AA peptide P6
γ-AA peptide P6 acts as a potent activator of E6 associated protein (E6AP), facilitating both its self-ubiquitination and the ubiquitination of E6AP substrates in vitro reconstituted reactions. Furthermore, γ-AA peptide P6 amplifies substrate ubiquitination within the cell, thereby expediting their proteasomal degradation [1].
价 格:¥电议型 号:T80686产 地:中国大陆
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T79686FGFR1 inhibitor-10;化合物 FGFR1 inhibitor-10FGFR1 inhibitor-10
FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation. This compound demonstrates anti-angiogenic and anti-invasion properties, as well as a significant anti-tumor effect [1].
价 格:¥电议型 号:T79686产 地:中国大陆
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T78686Apoptosis inducer 11;化合物 Apoptosis inducer 11Apoptosis inducer 11
Apoptosis Inducer 11 (compound 3u) promotes apoptosis via the mitochondrial pathway and elicits a G2/M block alongside a marked reduction in the S phase within non-Hodgkin lymphoma cell lines [1].
价 格:¥电议型 号:T78686产 地:中国大陆
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T776861-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone;化合物T776861-(4-AMinophenyl)-5,6-dihy
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone has broad-spectrum antifungal activity with inhibitory effects on Candida albicans, Aspergillus niger, Pseudomonas aeruginosa and Staphylococcus aureus.
价 格:¥电议型 号:T77686产 地:中国大陆
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T77440Codrituzumab;考曲妥珠单抗RG-7686|||RO5137382|||GC33;RG-7686|||RO5137382|||GC33
Codrituzumab (GC3) is a humanized antibody against the glypican-3 hepatocellular carcinoma protein that can be used in combination with sorafenib to study incurable advanced hepatocellular carcinoma (HCC).
价 格:¥电议型 号:T77440产 地:中国大陆
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T76869Lirentelimab;化合物 LirentelimabLirentelimab
Lirentelimab (AK002), a humanized IgG1 monoclonal antibody, specifically targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). It promotes apoptosis in IL-5-activated eosinophils and suppresses IgE-mediated activation of mast cells. This compound is under investigation for the treatment of eosinophilic gastritis and duodenitis [1].
价 格:¥电议型 号:T76869产 地:中国大陆
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T76868Lacnotuzumab;化合物 LacnotuzumabLacnotuzumab
Lacnotuzumab (MCS110), a humanized IgG1/κ monoclonal antibody, neutralizes and inhibits the interaction between CSF-1 and its receptor, CSF-1R. It is utilized in researching pigmented villonodular synovitis [1] [2].
价 格:¥电议型 号:T76868产 地:中国大陆
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T76867Ravulizumab;雷夫利珠单抗ALXN1210;ALXN1210
Ravulizumab (ALXN1210) is a humanized monoclonal antibody targeting complement factor 5 that specifically binds to human complement protein C5 with high affinity to block complement activation. Ravulizumab can be used for the prevention and treatment of paroxysmal sleep hemoglobinuria, atypical hemolytic uremic syndrome and myasthenia gravis.
价 格:¥电议型 号:T76867产 地:中国大陆
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T76866Icrucumab;艾芦库单抗LY 3012212|||IMC-18F1;LY 3012212|||IMC-18F1
Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab has been studied in metastatic colon cancer.
价 格:¥电议型 号:T76866产 地:中国大陆
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T76865Enavatuzumab;化合物 EnavatuzumabEnavatuzumab
Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody designed to target the TWEAK receptor (TweakR), a protein involved in various cellular responses through its interaction with its natural ligand, TWEAK (Fn14; TNFRSF12A). By directly engaging TweakR signaling and promoting antibody-dependent cell-mediated cytotoxicity (ADCC), enavatuzumab effectively inhibits tumor growth. It also recruits and activates myeloid effector cells to destroy tumor cells. Enavatuzumab has demonstra
价 格:¥电议型 号:T76865产 地:中国大陆
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T76864Enapotamab;Enapotamab单抗Enapotamab
Enapotamab is an AXL/UFO-related antibody that can be used to synthesize antibody-drug couplings (Enapotamab Vedotin).
价 格:¥电议型 号:T76864产 地:中国大陆
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T76863Elezanumab;依来努单抗AE12-1Y-QL|||ABT-555;AE12-1Y-QL|||ABT-555
Elezanumab(ABT-555) is a potent human anti-RGMa monoclonal antibody.Elezanumab exerts its inhibitory effect on RGMa-mediated BMP signaling through the SMAD1/5/8 pathway, with an IC50 of approximately 97 pM.Elezanumab promotes neuroregeneration, neuroprotection, and neural restoration in models of neuronal injury and demyelination. Elezanumab promotes the growth of corticospinal axons into spinal gray matter and enhances serotonergic innervation in the ventral horn, forming synaptic connections i
价 格:¥电议型 号:T76863产 地:中国大陆
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T76862Crotedumab;化合物 CrotedumabCrotedumab
Crotedumab (REGN1193), a fully human IgG4 monoclonal antibody, selectively binds to and inhibits the glucagon receptor (GCGR) with a dissociation constant (K D) of 0.1 nM, making it a potent candidate for diabetes research [1] [2].
价 格:¥电议型 号:T76862产 地:中国大陆
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T76861Cinpanemab;辛帕奈单抗BIIB054;BIIB054
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson´s disease and related diseases.
价 格:¥电议型 号:T76861产 地:中国大陆
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T7686Ramiprilat;雷米普利Ramiprilat
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
价 格:¥电议型 号:T7686产 地:中国大陆
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T76774Ponsegromab;Ponsegromab单抗PF 06946860;PF 06946860
Ponsegromab (PF 06946860) is a selective and effective humanized anti-GDF15 antibody inhibitor. Ponsegromab has anti-cachexic activity by binding to GDF15 to prevent its binding to GFRAL, thus disrupting GDF15/GFRAL mediated signaling. Ponsegromab has potential anticancer activity and can be used to treat cancer patients with cancer anorexia cachexia syndrome.
价 格:¥电议型 号:T76774产 地:中国大陆
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T7673ATH686;化合物ATH 686ATH 686;ATH 686
ATH686 is an potent and selective Inhibitor of FLT3.
价 格:¥电议型 号:T7673产 地:中国大陆
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T76686Lebrikizumab;化合物 LebrikizumabLebrikizumab
Lebrikizumab, an IgG4 humanized monoclonal antibody, specifically targets and inhibits interleukin-13 (IL-13), thus impacting its function. This compound is utilized in asthma research [1].
价 格:¥电议型 号:T76686产 地:中国大陆
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T75686Enfumafungin;化合物 EnfumafunginEnfumafungin
Enfumafungin, a triterpene glycoside extracted from Hormonema carpetanum fungus, acts as an antifungal by inhibiting (1,3)-beta-D-glucan synthase, crucial for fungal cell wall synthesis. It selectively targets yeasts and fungi, excluding Cryptococcus, without affecting Bacillus subtilis growth [1] [2].
价 格:¥电议型 号:T75686产 地:中国大陆
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T74686A947;化合物 A947A947
A947, a potent and selective SMARCA2 proteolysis-targeting chimera (PROTAC) molecule, also acts as a moderately selective SMARCA2 degrader. It exhibits strong binding affinity to the SMARCA2 bromodomain, with a dissociation constant (K d) of 93 nM, making it a valuable tool for cancer research [1].
价 格:¥电议型 号:T74686产 地:中国大陆