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T5721Dehydroevodiamine hydrochlorideDehydroevodiamine hydrochloride
Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.
价 格:¥电议型 号:T5721产 地:美洲
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T6058LY2886721LY2886721
LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer´s Disease.
价 格:¥电议型 号:T6058产 地:美洲
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T83721Hexafluoropropylene Oxide Dimer Acid;化合物 Hexafluoropropylene Oxide Dimer AcidFRD-903|||Perfluoro-2-p
Hexafluoropropylene oxide dimer acid (HFPO-DA), a perfluoroalkyl ether carboxylic acid (PFECA), shows diverse biological impacts across species. At 250 ?M, it triggers apoptosis and enhances reactive oxygen species (ROS) levels in HepG2 cells. In hatchling chickens, HFPO-DA at a dosage of 4 mg/kg per egg notably decreases right ventricular wall thickness, accelerates heart rate, and promotes hepatic lipid accumulation, though these effects are mitigable by silencing the Ppara gene. It significan
价 格:¥电议型 号:T83721产 地:中国大陆
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T82721Cinnamtannin B2;化合物 Cinnamtannin B2Cinnamtannin B2
Cinnamtannin B2 (compound 12), a tannin derivative found in cinnamon, has been isolated from the plant Vaccinium vitis-idaea L. [1].
价 格:¥电议型 号:T82721产 地:中国大陆
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T81721N,N-Dimethyldoxorubicin;化合物 N,N-DimethyldoxorubicinN,N-Dimethyldoxorubicin
N,N-Dimethyldoxorubicin, a Doxorubicin analogue, exhibits cytotoxicity against a range of tumor cell lines with IC50 values below 0.3 μM [1].
价 格:¥电议型 号:T81721产 地:中国大陆
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T80721Zndm19;化合物 Zndm19Zndm19
Zndm19 is an inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1), utilized in researching drug-resistant bacterial infections [1].
价 格:¥电议型 号:T80721产 地:中国大陆
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T79721GPR55 agonist 3;化合物 GPR55 agonist 3GPR55 agonist 3
Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55. It also induces β-arrestin recruitment to human GPR55 with an EC50 of 6.2 nM [1].
价 格:¥电议型 号:T79721产 地:中国大陆
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T78721Smurf1-IN-1;化合物 Smurf1-IN-1Smurf1-IN-1
Smurf1-IN-1, a selective E3 ubiquitin protein ligase 1 (SMURF1) inhibitor, exhibits oral activity with an IC50 of 92 nM and demonstrates considerable efficacy in a rat model of pulmonary hypertension [1].
价 格:¥电议型 号:T78721产 地:中国大陆
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T77219N-((Allyloxy)carbonyl)-N-methyl-L-alanine;化合物 N-((Allyloxy)carbonyl)-N-methyl-L-alanineN-((Allyloxy)
N-((Allyloxy)carbonyl)-N-methyl-L-alanine, an alanine derivative, serves as a precursor for the synthesis of complement factor D inhibitors, which are key in researching immune system-related diseases [1].
价 格:¥电议型 号:T77219产 地:中国大陆
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T77217Saccharopine hydrochloride;化合物 Saccharopine hydrochlorideSaccharopine hydrochloride
Saccharopine hydrochloride (L-Saccharopine hydrochloride), an intermediate in lysine degradation and a mitochondrial toxin, is produced through the conversion of lysine and α-ketoglutarate by lysine-ketoglutarate reductase. This compound is subsequently oxidized to α-aminoapidate semialdehyde and glutamate by saccharopine dehydrogenase, impairing development by disrupting mitochondrial homeostasis [1] [2] [3].
价 格:¥电议型 号:T77217产 地:中国大陆
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T77215Kanamycins sulfate;化合物 Kanamycins sulfateKanamycins sulfate
Kanamycin sulfate, a broad-spectrum antibiotic, is effective for treating severe staphylococcal or Gram-negative bacillary infections. This compound has been linked to ototoxicity [1] [2].
价 格:¥电议型 号:T77215产 地:中国大陆
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T77212L-α-lysophosphatidylinositol (Soy) (sodium);化合物 L-α-lysophosphatidylinositol (Soy) (sodium)L-α-lysop
L-α-Lysophosphatidylinositol Soy Sodium, an endogenous ligand of GPR55, is an endocannabinoid neurotransmitter and lysophospholipid. This compound falls within the class of lysophospholipids [1].
价 格:¥电议型 号:T77212产 地:中国大陆
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T77211Sudan I-d5;化合物 Sudan I-d5Sudan I-d5
Sudan I-d5, the deuterated variant of Sudan I, is a diazo-conjugate red dye utilized in oils, solvents, or polishes as an additive. Notably, it hampers the growth of bacterial strains Clostridium perfringens and L. rhamnosus[1].
价 格:¥电议型 号:T77211产 地:中国大陆
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T77210Poly(hexamethylenebiguanide) hydrochloride;化合物 Poly(hexamethylenebiguanide) hydrochloridePoly(hexame
Poly(hexamethylenebiguanide) hydrochloride, serving as an antimicrobial agent, finds applications across various fields including medical, apparel, and household textiles [1].
价 格:¥电议型 号:T77210产 地:中国大陆
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T76870Narsoplimab纳索利单抗OMS 721
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway activation. It can inhibit the agglutinin pathway. Narsoplimab can be used to study diseases associated with hematopoietic stem cell transplantation in adults.
价 格:¥电议型 号:T76870产 地:中国大陆
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T76721Zalutumumab;化合物 ZalutumumabZalutumumab
Zalutumumab, a fully human IgG1 monoclonal antibody, exhibits high affinity for the epidermal growth factor receptor (EGFR), selectively targeting its domain III. It functions by inhibiting the binding of the epidermal growth factor (EGF) and obstructing the receptor´s active conformation through steric hindrance. With EC50 values of 7 nM for its IgG and 19 nM for the Fab fragment, Zalutumumab demonstrates potent interaction capabilities. This compound is primarily utilized in cancer resea
价 格:¥电议型 号:T76721产 地:中国大陆
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T75721ATI-2341 TFA;化合物 ATI-2341 TFAATI-2341 TFA
ATI-2341 is a potent, functionally selective allosteric agonist of the C-X-C chemokine receptor type 4 (CXCR4), acting as a biased ligand that prefers Gαi activation over Gα13. This compound activates the inhibitory heterotrimeric G protein (Gi), leading to reduced cAMP production and enhanced calcium mobilization. ATI-2341 effectively mobilizes bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) [1] [2].
价 格:¥电议型 号:T75721产 地:中国大陆
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T74721Lipid 29;化合物 Lipid 29Lipid 29
Lipid 29, an ionizable amino lipid, can be utilized to create lipid nanoparticles [1].
价 格:¥电议型 号:T74721产 地:中国大陆
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T73721Phleomycin D1;化合物 Phleomycin D1Phleomycin D1
Phleomycin D1 (PLM D1), a glycopeptide antibiotic within the Bleomycin/Phleomycin family, induces cell death through DNA binding and cleavage [1] [2] [3].
价 格:¥电议型 号:T73721产 地:中国大陆
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T72721PD-1/PD-L1-IN-29;化合物 PD-1/PD-L1-IN-29PD-1/PD-L1-IN-29
PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM. It effectively binds to PD-L1, inhibiting the PD-1/PD-L1 interaction, promotes PD-L1 dimerization and its internalization, enhances localization to the endoplasmic reticulum, and facilitates PD-L1´s entry into the endoplasmic reticulum, demonstrating anticancer activity.
价 格:¥电议型 号:T72721产 地:中国大陆