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T79912NSC309401;化合物 NSC309401NSC309401
NSC309401 is an E. coli dihydrofolate reductase inhibitor, displaying potency with an IC50 value of 189 nM and a dissociation constant (KD) of 14.57 nM [1].
价 格:¥电议型 号:T79912产 地:中国大陆
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T79911O-Benzoylhydroxylamine;化合物 O-BenzoylhydroxylamineO-Benzoylhydroxylamine
O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].
价 格:¥电议型 号:T79911产 地:中国大陆
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T79910Cyclophellitol aziridine;化合物 Cyclophellitol aziridineCyclophellitol aziridine
Cyclophellitol aziridine, an analogue of cyclophenol, serves as a potent inhibitor of β-glucosidase [1].
价 格:¥电议型 号:T79910产 地:中国大陆
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T79912-Hydroxycinnamic acid(E)-3-(2-羟基苯基)丙烯酸邻羟基肉桂酸(邻香豆酸)|||(E)-3-(2-羟基苯基)丙烯酸
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.
价 格:¥电议型 号:T7991产 地:中国大陆
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T79021GSK3839919A;化合物 GSK3839919AGSK3839919A
GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].
价 格:¥电议型 号:T79021产 地:中国大陆
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T78991Biotin-labeled ODN 1585 sodium;化合物 Biotin-labeled ODN 1585 sodiumBiotin-labeled ODN 1585 sodium
Biotin-labeled ODN 1585 (sodium) serves as a potent inducer of IFN and TNFα production and facilitates the assessment of CpG ODN cellular uptake and localization through detection with a biotin system and light microscopy analysis.
价 格:¥电议型 号:T78991产 地:中国大陆
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T78570XE991;化合物 XE991XE991
XE991 is a novel and selective Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current, and can be used for the study of neurological diseases.
价 格:¥电议型 号:T78570产 地:中国大陆
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T77991Glutaurine TFA;化合物 Glutaurine TFALitoralon TFA;Litoralon TFA
Glutaurine (Litoralon) TFA, a compound featuring glutamine and taurine residues, functions as an orally active parathyroid hormone. Originating from the oxyphil cells of the parathyroid gland, this hormone is employed in the study of antiepileptic and anti-amnesia treatments, as evidenced by references [1] [2] [3] [4].
价 格:¥电议型 号:T77991产 地:中国大陆
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T76991Suvizumab;化合物 SuvizumabSuvizumab
Suvizumab (KD-247), a neutralizing antibody against HIV-1, effectively neutralizes strains HIV-1 MN, HIV-1 SF2, and HIV-1 89.6, exhibiting IC50 values of 0.1 ?g/mL, 1.0 ?g/mL, and 0.2 ?g/mL, respectively. It demonstrates a significant reduction in viral load, indicating its efficacy in preventing HIV infection. Suvizumab is also well-tolerated, further supporting its potential as a preventative treatment for HIV [1] [2].
价 格:¥电议型 号:T76991产 地:中国大陆
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T76891Oxelumab;奥塞芦单抗Ro 49-89991|||R 4930|||huMAb OX 40L;Ro 49-89991|||R 4930|||huMAb OX 40L
Oxelumab (R 4930) is a human monoclonal antibody for OX40L. Oxelumab could be used to study asthma.
价 格:¥电议型 号:T76891产 地:中国大陆
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T75991Ganirelix;化合物 GanirelixGanirelix
Ganirelix is a selective and competitive antagonist of gonadotropin-releasing hormone (GnRH), effectively preventing endogenous GnRH from triggering the release of luteinizing hormone (LH) and follicle-stimulating hormone [1].
价 格:¥电议型 号:T75991产 地:中国大陆
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T74991Dual AChE-MAO B-IN-3;化合物 Dual AChE-MAO B-IN-3Dual AChE-MAO B-IN-3
Dual AChE-MAO B-IN-3 (Compound C10) is a potent inhibitor of both AChE and MAO-B, exhibiting IC50 values of 0.58 μM and 0.41 μM, respectively. This dual-binding inhibitor targets the catalytic anionic site and peripheral anionic site of AChE, making it relevant for Alzheimer’s disease (AD) research [1].
价 格:¥电议型 号:T74991产 地:中国大陆
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T74912ODN 24991;化合物 ODN 24991ODN 24991
ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN) derivative of INH-ODN 2088, inhibits Toll-like receptors (TLR) 3, TLR7, and TLR9, thereby attenuating TLR3-, TLR7-, and TLR9-mediated immune responses. The sequence of ODN 24991 is 5´-C-C-T-G-G-C-c7rGm-G-G-G-3´ [1].
价 格:¥电议型 号:T74912产 地:中国大陆
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T73148ACT-777991;化合物 ACT-777991ACT-777991
ACT-777991 is an orally active, selective CXCR3 antagonist with demonstrated stability in microsomes and hepatocytes across various animal models. This compound effectively inhibits the migration of activated T cells toward CXCL11.
价 格:¥电议型 号:T73148产 地:中国大陆
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T73132DS69910557;化合物 DS69910557DS69910557
DS69910557, a potent, selective, and orally active antagonist of the human parathyroid hormone receptor 1 (hPTHR1), exhibits antagonistic activity with an IC50 value of 0.08 μM. It is useful in researching hyperparathyroidism, hypercalcemia of malignancy, and osteoporosis.
价 格:¥电议型 号:T73132产 地:中国大陆
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T72991Bis-Pro-5FU;化合物 Bis-Pro-5FUBis-Pro-5FU
Bis-Pro-5FU, a precursor to 5-Fluorouracil (5-FU), enhances the oral bioavailability and safety profile of 5-FU chemotherapy treatments. 5-FU itself is an antineoplastic antimetabolite extensively utilized in the research of colorectal and pancreatic cancer.
价 格:¥电议型 号:T72991产 地:中国大陆
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T72743(R)-PF-04991532;化合物 (R)-PF-04991532(R)-PF-04991532
(R)-PF-04991532 is the R-enantiomer of PF-04991532 . PF-04991532 is a potent, hepatoselective glucokinase activator .
价 格:¥电议型 号:T72743产 地:中国大陆
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T72507Palbociclib orotate;化合物 Palbociclib orotatePD 0332991 orotate;PD 0332991 orotate
Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively. This compound demonstrates potent anti-proliferative effects and induces cell cycle arrest in cancer cells, applicable in research concerning HR-positive, HER2-negative breast cancer, and hepatocellular carcinoma [1] [3] [4].
价 格:¥电议型 号:T72507产 地:中国大陆
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T71991PUN-96956;化合物 PUN-96956PUN-96956
PUN-96956 is a novel BAM complex inhibitor, interfering with BamA-related processes and affect folding and insertion of OMPs. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).
价 格:¥电议型 号:T71991产 地:中国大陆
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T70991Efrapeptin F;化合物 Efrapeptin FEfrapeptin F
Efrapeptin F is a metabolite of entomogenous fungi in the genus Tolypocladium that acts as a mitochondrial complex V inhibitor. It has been shown to express preferential cytotoxicity to nutrient-deprived tumor cells compared with nutrient-sufficient tumor cells.
价 格:¥电议型 号:T70991产 地:中国大陆