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T1003610β,17β-dihydroxyestra-1,4-dien-3-one10β,17β-dihydroxyestra-1,4-dien-3-one,DHED,
10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
价 格:¥电议型 号:T10036产 地:美洲
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T10353APX-115 free baseAPX-115 free base,Ewha-18278 free base,
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
价 格:¥电议型 号:T10353产 地:美洲
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T10354APX-115APX-115,Ewha-18278,
APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
价 格:¥电议型 号:T10354产 地:美洲
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T11317FPA-124FPA-124
FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt.?FPA-124 induces apoptosis.?FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM.?
价 格:¥电议型 号:T11317产 地:美洲
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T1146NifedipineNifedipine,BAY-a-1040,Procardia
Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and
价 格:¥电议型 号:T1146产 地:美洲
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T12910Sigma-1 receptor antagonist 1Sigma-1 receptor antagonist 1
Sigma-1 receptor antagonist 1 is a potent and selective antagonist of sigma-1 receptor (σ1R) with Ki of 1.06 nM, has antineuropathic pain activity.
价 格:¥电议型 号:T12910产 地:美洲
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T12911Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
价 格:¥电议型 号:T12911产 地:美洲
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T12912Sigma-1 receptor antagonist 3Sigma-1 receptor antagonist 3
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
价 格:¥电议型 号:T12912产 地:美洲
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T13073Taltobulin trifluoroacetateTaltobulin trifluoroacetate,HTI-286 trifluoroacetate,SPA-110 trifluoroace
Taltobulin trifluoroacetate is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
价 格:¥电议型 号:T13073产 地:美洲
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T13112Tat-NR2B9cTat-NR2B9c,NA-1,
Tat-NR2B9c is a 20-aa peptide, and acts as a postsynaptic density-95 (PSD-95) inhibitor(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.
价 格:¥电议型 号:T13112产 地:美洲
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T13112LTat-NR2B9c TFATat-NR2B9c TFA,NA-1 (TFA),
Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.
价 格:¥电议型 号:T13112L产 地:美洲
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T14067A-1165442A-1165442
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
价 格:¥电议型 号:T14067产 地:美洲
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T2359ANA-12ANA-12,ANA12,ANA 12
ANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.
价 格:¥电议型 号:T2359产 地:美洲
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T2366Tipiracil hydrochlorideTipiracil hydrochloride,MA-1 hydrochloride,
Tipiralacil is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials.
价 格:¥电议型 号:T2366产 地:美洲
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T2632A-1210477A-1210477,A1210477,A 1210477
A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).
价 格:¥电议型 号:T2632产 地:美洲
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T2662Alda-1Alda-1,Alda 1,
Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH2*1 and the Asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).
价 格:¥电议型 号:T2662产 地:美洲
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T5315TCA-1TCA-1,TCA1,TCA 1
TCA-1 is a small molecule with activity against drug-resistant and persistent tuberculosis.
价 格:¥电议型 号:T5315产 地:美洲
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T5621p-mentha-1(7),2-dienep-mentha-1(7),2-diene,beta-Phellandrene,
p-mentha-1(7),2-diene is found in allspice. beta-Phellandrene is widely distributed in essential oils?
价 格:¥电议型 号:T5621产 地:美洲
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T8681HA-1004 dihydrochloride;HA 1004 盐酸盐HA-1004 dihydrochloride
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
价 格:¥电议型 号:T8681产 地:中国大陆