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  • T6759LAP-III-a4 hydrochloride (1177827-73-4 free base)；化合物 T6759LENOblock hydrochloride|||AP-III-a4 hydroc

    AP-III-a4 hydrochloride (ENOblock hydrochloride) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. IC50 value: 0.576 uM [1] Target: enolase Enolase is a component of the glycolysis pathway and a "moonlighting" protein, with important roles in diverse cellular processes that are not related to its function in glycolysis. However, small molecule tools to pro

    价 格：￥电议型 号：T6759L产 地：中国大陆

  • T6759AP-III-a4；化合物AP-III-a4ENOblock；ENOblock

    AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.

    价 格：￥电议型 号：T6759产 地：中国大陆

  • T65210Gibberellin A4；化合物 Gibberellin A4Gibberellin A4

    Gibberellin A4 is a natural product for research related to life sciences. The catalog number is T65210 and the CAS number is 468-44-0.

    价 格：￥电议型 号：T65210产 地：中国大陆

  • T64037CYP3A4-IN-2；化合物 CYP3A4-IN-2CYP3A4-IN-2

    CYP3A4-IN-2 is a specific inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.055 μM). CYP3A4-IN-2 is a ritonavir analogue with a more hydrophobic R2 side group and stronger inhibition than ritonavir. CYP3A4-IN-2 is capable of acting as an immunosuppressive and antiviral agent.

    价 格：￥电议型 号：T64037产 地：中国大陆

  • T64032CYP3A4-IN-3；化合物 CYP3A4-IN-3CYP3A4-IN-3

    CYP3A4-IN-3 is a specific, highly affinity cytochrome P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) inhibitor (IC50: 0.075 μM). CYP3A4-IN-3 is an analogue of ritonavir with a simpler structure and twice as much inhibition as ritonavir. CYP3A4-IN-3 can be used as an antiviral agent and immunosuppressant.

    价 格：￥电议型 号：T64032产 地：中国大陆

  • T63954CYP3A4-IN-1；化合物 CYP3A4-IN-1CYP3A4-IN-1

    CYP3A4-IN-1 is a potent inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.085 μM).

    价 格：￥电议型 号：T63954产 地：中国大陆

  • T6272Fosbretabulin Disodium；福他布林Combretastatin A4 Phosphate|||CA 4DP|||CA 4P|||Combretastatin A4 disodium

    Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50: 2.4 μM), and also disrupts tumor vasculature.

    价 格：￥电议型 号：T6272产 地：中国大陆

  • T60647A4B17；化合物 A4B17A4B17

    A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.

    价 格：￥电议型 号：T60647产 地：中国大陆

  • T4431Olodanrigan；化合物EMA401PD-126055|||EMA401；PD-126055|||EMA401

    Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA401 blocks p38, p42/p44 mitogen-activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons induced by AngII. It inhibits capsaicin responses in cultured hDRG neurons.

    价 格：￥电议型 号：T4431产 地：中国大陆

  • T413524α-TPA；化合物 4α-TPA4α-TPA

    4α-TPA has a wide range of applications in life science related research.

    价 格：￥电议型 号：T41352产 地：中国大陆

  • T40659γ-Acetylenic GABAγ-Acetylenic GABA4-Aminohex-5-ynoic acid|||γ-Acetylenic GABA

    γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase. This compound effectively raises the concentration of γ-Aminobutyric acid (GABA) in the brain of rats.

    价 格：￥电议型 号：T40659产 地：中国大陆

  • T38290Leucomycin A4；Leucomycin A4Leucomycin A4；Leucomycin A4

    Leucomycin A4 is a macrolide antibiotic that has been found in S. kitasatoensis. It is active against a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 μg/ml, respectively).

    价 格：￥电议型 号：T38290产 地：中国大陆

  • T381204-MUNANA；化合物4-MUNANA4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid sodium salt；4-Methylumbellifer

    4-MUNANA is a fluorescent substrate used in neuraminidase activity assays and is a neuraminidase substrate analogue.4-MUNANA is a fluorescent substrate used in neuraminidase activity assays and is a neuraminidase substrate analogue.

    价 格：￥电议型 号：T38120产 地：中国大陆

  • T37616Leukotriene A4 methyl ester；Leukotriene A4 methyl esterLeukotriene A4 methyl ester；Leukotriene A4 me

    Leukotriene A4 methyl ester can be converted into leukotriene C4 monomethyl ester catalyzed by the major alkaline cytosolic glutathione transferase in rat liver, which can be used in metabolism-related studies.

    价 格：￥电议型 号：T37616产 地：中国大陆

  • T37498Antimycin A4；Antimycin A4Antimycin A4

    Antimycin A4 is an active component of the antimycin A antibiotic complex that is more polar than antimycin A1 , antimycin A2 , and antimycin A3 . Antimycin A4 inhibits ATP-citrate lyase with a Ki value of 64.8 μM. The antimycin A complex is a mixture of antimycins A1, A2, A3, and A4 that demonstrates antifungal, insecticidal, nematocidal, and piscicidal properties. It blocks mitochondrial respiration and can deplete cellular levels of ATP via inhibition of complex III of the mitochondrial elect

    价 格：￥电议型 号：T37498产 地：中国大陆

  • T373056(S)-Lipoxin A4；6(S)-Lipoxin A46Lipoxin A4|||6(S)-Lipoxin A4|||6(S)-Lipoxin A4|||6(S) Lipoxin A4|||6

    The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to b

    价 格：￥电议型 号：T37305产 地：中国大陆

  • T3726515(R)-Lipoxin A4；15(R)-Lipoxin A415(R)-Lipoxin A4|||AT-Lipoxin A4；15(R)-Lipoxin A4|||AT-Lipoxin A4

    Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may

    价 格：￥电议型 号：T37265产 地：中国大陆

  • T368934-oxo Withaferin A4-oxo Withaferin A4 oxo Withaferin A|||4oxo Withaferin A

    4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.

    价 格：￥电议型 号：T36893产 地：中国大陆

  • T36052Lipoxin A4 methyl ester；Lipoxin A4 methyl esterLXA4 methyl ester；LXA4 methyl ester

    Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM.[2] LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural

    价 格：￥电议型 号：T36052产 地：中国大陆

  • T36051Lipoxin A4；脂氧素 A4LXA4；脂氧素 A4|||LXA4

    Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide generation in human neutrophils at 0.1 μM.2 LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.[2],[3],[4] Analytical and biological comparisons of synth

    价 格：￥电议型 号：T36051产 地：中国大陆

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