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T74742TRPV1 activator-2；化合物 TRPV1 activator-2TRPV1 activator-2
TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].
价 格：￥电议型 号：T74742产 地：中国大陆
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T74741TRPV1 activator-1；化合物 TRPV1 activator-1TRPV1 activator-1
TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].
价 格：￥电议型 号：T74741产 地：中国大陆
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T72770p53 Activator 5；化合物 p53 Activator 5p53 Activator 5
P53 Activator 5 is a potent activator of p53, exhibiting a SC150 value of less than 0.05 mM. It effectively binds to mutant p53, restoring its DNA-binding capability. Additionally, P53 Activator 5 demonstrates significant anti-tumor activity.
价 格：￥电议型 号：T72770产 地：中国大陆
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T72769p53 Activator 3；化合物 p53 Activator 3p53 Activator 3
p53 Activator 3 is a potent activator of p53, demonstrating notable efficacy with an SC150 value of less than 0.05 mM. It effectively binds to mutant p53, reinstating its DNA-binding capability, and exhibits anti-tumor activity.
价 格：￥电议型 号：T72769产 地：中国大陆
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T72697Nrf2 activator-6；化合物 Nrf2 activator-6Nrf2 activator-6
Nrf2 Activator-6, a tetrahydroisoquinoline compound, functions as an Nrf2 activator, demonstrating potency with an IC50 value of 5 nM in inhibiting the Kelch domain-Nrf2 interaction.
价 格：￥电议型 号：T72697产 地：中国大陆
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T72693PKM2 activator 5；PKM2 激活剂5PKM2 activator 5
PKM2 activator 5 is a novel and potent PKM2 activator (AC50: 0.316 ?M) with potential anticancer activity for the study of cancer metabolism-related diseases.
价 格：￥电议型 号：T72693产 地：中国大陆
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T72692PKM2 activator 4；化合物 PKM2 activator 4PKM2 activator 4
PKM2 Activator 4, a chemical compound, functions as an activator of PKM2 with an activation concentration (AC 50) ranging from 1 to 10 μM. It is primarily utilized in cancer research.
价 格：￥电议型 号：T72692产 地：中国大陆
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T72690AMPK activator 9；化合物 AMPK activator 9AMPK activator 9
AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 ?M, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its potential application in understanding and possibly treating this condition.
价 格：￥电议型 号：T72690产 地：中国大陆
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T72623Nampt activator-3；化合物 Nampt activator-3Nampt activator-3
NAMPT Activator-3, a derivative of NAT, is a potent activator of NAMPT, demonstrating an EC50 of 2.6 μM and KD of 132 nM. It effectively shields cultured cells against toxicity induced by FK866 and has demonstrated significant neuroprotective effects in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model, without any apparent toxicity [1].
价 格：￥电议型 号：T72623产 地：中国大陆
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T72617Nampt activator-2；Nampt激活剂2Nampt activator-2
Nampt activator-2 is a NAMPT activator (EC50: 0.023 μM). Nampt activator-2 has an affinity for CYP2C9, 2D6, and 2C19 with affinity values of 0.060 μM, 0.41 μM, and 0.59 μM, respectively.Nampt activator-2 can be used in the study of atherosclerosis, obesity, type II diabetes, insulin resistance, and type I diabetes.
价 格：￥电议型 号：T72617产 地：中国大陆
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T72484SIRT6 activator 12q；化合物 SIRT6 activator 12qSIRT6 activator 12q
SIRT6 activator 12q is a potent, selective, and orally active compound that activates SIRT6. It demonstrates IC50 values of 171.20 μM for SIRT1, >200 μM for SIRT2, SIRT3, and SIRT5, and 0.58 μM for SIRT6, indicating its high specificity towards SIRT6. This compound effectively inhibits cell growth and migration, induces apoptosis, and causes cell cycle arrest at the G2 phase, showcasing its anticancer activity.
价 格：￥电议型 号：T72484产 地：中国大陆
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T72420MTK458；化合物 MTK458Mitophagy activator 1|||EP-0035985；Mitophagy activator 1|||EP-0035985
MTK458 (EP-0035985) is an orally active and brain-permeable PINK1 activator that promotes pathological clearance of alpha-synuclein and reduces pUb in a PFF inoculation model.MTK458 induces pathological alpha-synuclein clearance by stimulating dimerization and stabilization of the PINK1/TOM complex.MTK458 may be used in Parkinson´s disease research.
价 格：￥电议型 号：T72420产 地：中国大陆
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T72316Caspase-3/7 activator 3；化合物 Caspase-3/7 activator 3Caspase-3/7 activator 3
Caspase-3/7 Activator 3 is a potent and tumor-selective compound that effectively activates Caspase-3/7, demonstrating significant anti-proliferative activity and a high capacity to induce apoptosis.
价 格：￥电议型 号：T72316产 地：中国大陆
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T72315Caspase-3/7 activator 2；化合物 Caspase-3/7 activator 2Caspase-3/7 activator 2
Caspase-3/7 Activator 2 is a potent compound that selectively activates Caspase-3/7, demonstrating tumor specificity, anti-proliferative properties, and a high capacity for inducing apoptosis.
价 格：￥电议型 号：T72315产 地：中国大陆
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T72227PI3K/Akt/CREB activator 1；化合物 PI3K/Akt/CREB activator 1PI3K/Akt/CREB activator 1
PI3K/Akt/CREB Activator 1 is a potent, orally active compound that acts as an activator for the PI3K/Akt/CREB pathway. It enhances neuronal proliferation, induces differentiation of Neuro-2a cells into neuron-like morphology, and accelerates axon-dendrite polarization in primary hippocampal neurons by upregulating brain-derived neurotrophic factor. This compound is utilized in vascular dementia (VaD) research.
价 格：￥电议型 号：T72227产 地：中国大陆
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T72195KCa1.1 channel activator-2；化合物 KCa1.1 channel activator-2KCa1.1 channel activator-2
KCa1.1 channel activator-2, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels. This compound demonstrates significant myorelaxant activity.
价 格：￥电议型 号：T72195产 地：中国大陆
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T72194KCa1.1 channel activator-1；化合物 KCa1.1 channel activator-1KCa1.1 channel activator-1
KCa1.1 Channel Activator-1, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels while also blocking CaV1.2 channels. Additionally, it demonstrates weak myorelaxant activity.
价 格：￥电议型 号：T72194产 地：中国大陆
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T71714hClpP-activator-D9；化合物 hClpP-activator-D9hClpP-activator-D9
hClpP-activator-D9 is a novel potent and species-selective activator of human ClpP (hClpP).
价 格：￥电议型 号：T71714产 地：中国大陆
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T71580EBV activator C60；化合物 EBV activator C60EBV activator C60
EBV activator C60 is an EBV activator, and a well-performing EBV lytic cycle inducer.
价 格：￥电议型 号：T71580产 地：中国大陆
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T71336CASP3 Activator 1541B；化合物 CASP3 Activator 1541BCASP3 Activator 1541B
CASP3 Activator 1541B is an activator of the proenzyme forms of caspase-3, and is an inducer of cell death.
价 格：￥电议型 号：T71336产 地：中国大陆
