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T64302XIAP/cIAP1 antagonist-1;化合物 XIAP/cIAP1 antagonist-1XIAP/cIAP1 antagonist-1
XIAP/cIAP1 antagonist-1 is a potent, orally active XIAP/cIAP1 antagonist that acts on XIAP (EC50: 5.1 nM) and cIAP1 (EC50: 0.32 nM). xIAP/cIAP1 antagonist-1 dose-dependently inhibits tumour growth in vivo.
价 格:¥电议型 号:T64302产 地:中国大陆
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T64024Dopamine D3 receptor antagonist-1;化合物 Dopamine D3 receptor antagonist-1Dopamine D3 receptor antagoni
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic potential for central nervous system disorders.
价 格:¥电议型 号:T64024产 地:中国大陆
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T63947GRPR antagonist-1;化合物 GRPR antagonist-1GRPR antagonist-1
GRPR antagonist-1 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and is cytotoxic to certain cancer cells (able to act on PC3 cells (IC50: 4.97 μM), Pan02 cells (IC50: 4.36 μM), HGC-27 cells (IC50: 3.40 μM)). antagonist-1 was able to reduce the level of Bcl-2 and increase the level of Bax, thereby inhibiting the viability of HGC-27 cells and causing apoptosis, and exhibited anti-cancer effects.
价 格:¥电议型 号:T63947产 地:中国大陆
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T63893Adenylyl cyclase type 2 agonist-1;化合物 Adenylyl cyclase type 2 agonist-1Adenylyl cyclase type 2 agoni
Adenylyl cyclase type 2 agonist-1 is a potent agonist of adenylyl cyclase type 2 (AC2) (EC50: 90 nM). It is a potential lead compound in the fight against respiratory diseases.
价 格:¥电议型 号:T63893产 地:中国大陆
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T63868α5β1 integrin agonist-1;化合物 α5β1?integrin agonist-1α5β1 integrin agonist-1
α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.
价 格:¥电议型 号:T63868产 地:中国大陆
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T63578Mrgx2 antagonist-1;化合物 Mrgx2 antagonist-1Mrgx2 antagonist-1
Mrgx2 antagonist-1 is a potent antagonist of Mrgx2 (Mas-related Gene X2) and can be used to study Mrgx2-mediated diseases and disorders.
价 格:¥电议型 号:T63578产 地:中国大陆
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T63458STING agonist-11;化合物 STING agonist-11STING agonist-11
STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.
价 格:¥电议型 号:T63458产 地:中国大陆
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T63457STING agonist-10;化合物 STING agonist-10STING agonist-10
STING agonist-10 is a potent activator of the STING small molecule cyclic urea class (EC50: 2600 nM).STING activation is a highly promising immunotherapy.
价 格:¥电议型 号:T63457产 地:中国大陆
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T62856FFA1 agonist-1;化合物 FFA1 agonist-1FFA1 agonist-1
FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor (FFA1) agonist (EC50: 0.75 μM).
价 格:¥电议型 号:T62856产 地:中国大陆
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T62641EP2 receptor antagonist-1;化合物 EP2 receptor antagonist-1EP2 receptor antagonist-1
EP2 receptor antagonist-1 is a reversible, potent, agonist-dependent variant of the prostaglandin EP2 receptor antagonist.EP2 receptor antagonist-1 exhibits anti-inflammatory activity.
价 格:¥电议型 号:T62641产 地:中国大陆
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T62583CBR Agonist-1;化合物 CBR Agonist-1CBR Agonist-1
CBR Agonist-1 (27a-cis) is a cannabinoid receptor (CBR) agonist that acts on CB1R (Ki: 0.18 μM) and CB2R (Ki: 1.22 μM). CBR Agonist-1 (27a-cis) can be used to study endogenous cannabinoid system-related diseases.
价 格:¥电议型 号:T62583产 地:中国大陆
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T62502TREM2 agonist-1;化合物 TREM2 agonist-1TREM2 agonist-1
TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells-2 (TREM2) agonist (EC50: 3.0 μM-100 μM).
价 格:¥电议型 号:T62502产 地:中国大陆
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T62488P2X7 receptor antagonist-1;化合物 P2X7 receptor antagonist-1P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.
价 格:¥电议型 号:T62488产 地:中国大陆
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T62325CXCR7 antagonist-1 hydrochloride;化合物 CXCR7 antagonist-1 hydrochlorideCXCR7 antagonist-1 hydrochlorid
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. hydrochloride can be used for the prevention of tumour cell proliferation, tumour formation, inflammatory diseases and many other diseases.
价 格:¥电议型 号:T62325产 地:中国大陆
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T62173GPR41 agonist-1;化合物 GPR41 agonist-1GPR41 agonist-1
GPR41 agonist-1 (compound 9) is a potent agonist of GPR41 and can be used in studies of insulin-related diseases.
价 格:¥电议型 号:T62173产 地:中国大陆
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T618375-HT6/5-HT2AR antagonist-1;化合物 5-HT6/5-HT2AR antagonist-15-HT6/5-HT2AR antagonist-1
5-HT6/5-HT2AR antagonist-1 is a powerful and effective compound that acts as a dual antagonist for both the 5-HT6 and 5-HT2A receptors. It exhibits high potency with K i values of 11 nM and 39 nM for the respective receptors [1].
价 格:¥电议型 号:T61837产 地:中国大陆
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T61347D4R antagonist-1;化合物 D4R antagonist-1D4R antagonist-1
D4R Antagonist-1, characterized by its potent and selective antagonistic action against D4 receptors with an IC50 value of 6.87 μM, holds potential for Parkinson’s disease research [1].
价 格:¥电议型 号:T61347产 地:中国大陆
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T61144Hepcidin antagonist-1;Hepcidin 拮抗剂1Hepcidin antagonist-1
Hepcidin antagonist-1 is an iron-modulating antagonist.Hepcidin antagonist-1 can be used to study metabolic disorders such as iron-deficiency diseases and anemia.
价 格:¥电议型 号:T61144产 地:中国大陆
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T61026CaV1.3 antagonist-1;化合物 CaV1.3 antagonist-1CaV1.3 antagonist-1
CaV1.3 antagonist-1 is a cyclopentyl derivative with the potential for the research of Parkinson´s disease. CaV1.3 antagonist-1 inhibits Ca V 1.3 LTCC over 600-fold more effectively than Ca V 1.2 LTCC. CaV1.3 antagonist-1 is a potent and highly selective antagonist of Ca V 1.3 L-type calcium channel (LTCC) with an IC50 value of 1.7 μM [1].
价 格:¥电议型 号:T61026产 地:中国大陆
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T60917Dopamine D4 receptor antagonist-1;化合物 Dopamine D4 receptor antagonist-1Dopamine D4 receptor antagoni
Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.2 is 9.0 nM [1].
价 格:¥电议型 号:T60917产 地:中国大陆