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T35799MBX-8025 (sodium salt);MBX-8025 (sodium salt)MBX-8025 (sodium salt)
MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increases in fasting blood glucose and serum insulin levels, and decreases insulin resistance in Alms1 mutant (foz/foz) mice fed an atherogenic diet as a model of diet-induced obesity, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).2 It also decreases serum alanine transamin
价 格:¥电议型 号:T35799产 地:中国大陆
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T34925Triafamone;化合物 T34925BCS BX60309|||BCSBX60309|||BCS-BX60309;BCS BX60309|||BCSBX60309|||BCS-BX60309
Triafamone is a new sulfonanilide herbicide.
价 格:¥电议型 号:T34925产 地:中国大陆
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T32612LBX192;化合物 T32612NVP-LBX-192|||LBX-192|||LBX 192|||NVP-LBX192|||NVP-LBX 192;NVP-LBX-192|||LBX-192|||
LBX192( NVP-LBX192) is a liver-targeted glucokinase activator.
价 格:¥电议型 号:T32612产 地:中国大陆
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T32599Lauroylglycyrrhetinic acid;化合物 T32599BX 24|||BX24|||BX-24;BX 24|||BX24|||BX-24
Lauroylglycyrrhetinic acid, an analog of carbenoxolone, can be used in the treatment of stomach ulcer.
价 格:¥电议型 号:T32599产 地:中国大陆
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T31570DPBX-L-Dopa;化合物 T31570DPBX L-Dopa;DPBX L-Dopa
DPBX-L-Dopa is a boron-containing dopa-derivative, acting as a bladder relaxant through non-catecholamine receptors.
价 格:¥电议型 号:T31570产 地:中国大陆
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T31038CP-114271;化合物 T31038CP 114271|||UL-TG 307|||CP114271|||UNII-CY8W406YBX|||UL-TG-307;CP 114271|||UL-TG
CP-114271 is a bio-active chemical.
价 格:¥电议型 号:T31038产 地:中国大陆
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T30443BIBX 1382 Dihydrochloride;化合物 T30443Falnidamol dihydrochloride|||BIBX1382 Dihydrochloride|||BIBX-138
BIBX 1382 Dihydrochloride prevents Lassa and Ebola virus glycoprotein-dependent cells from entering the body. It can be used as a tool to understand conserved virus-host interactions and suggests that host cell kinases may be targets for broad-spectrum therapeutic interventions.
价 格:¥电议型 号:T30443产 地:中国大陆
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T28440PPD 10558化合物 T28440PPD-10558|||RBx10558|||RBx-10558|||PPD10558|||RBx 10558
PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.
价 格:¥电议型 号:T28440产 地:中国大陆
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T27983MBX2546;化合物 T27983MBX-2546|||MBX 2546;MBX-2546|||MBX 2546
MBX2546 is an Influenza A Virus Fusion Inhibitor. MBX2546 binds to HA and inhibits HA-mediated membrane fusion. Both binding and stabilization of HA by MBX2546 are required for the inhibition of viral infection. Mutations in MBX2546-resistant influenza A/PR/8/34 (H1N1) viruses are mapped in the HA stem region near the amino terminus of HA2.
价 格:¥电议型 号:T27983产 地:中国大陆
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T27318Fidexaban;非地沙班CI-1031|||BX-807834|||PD-200022|||CI1031|||BX807834|||ZK-807834;CI-1031|||BX-807834|||
Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
价 格:¥电议型 号:T27318产 地:中国大陆
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T26932BX 667;化合物 T26932BX-667|||BX667;BX-667|||BX667
BX 667 is a P2Y12 receptor antagonist. BX 667 blocks ADP-induced platelet aggregation in human, dog and rat blood with IC50 value of 97, 317 and 3000 nM respectively.
价 格:¥电议型 号:T26932产 地:中国大陆
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T26931BX 048;化合物 T26931BX048|||BX-048;BX048|||BX-048
BX 048 is an active metabolite of BX 667, an antagonist of P2Y12 adenosine diphosphate receptor for inhibition of platelet aggregation.
价 格:¥电议型 号:T26931产 地:中国大陆
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T26660Arterolane maleate;化合物 T26660RBx 11160|||OZ-277|||OZ277|||OZ 277|||RBx-11160;RBx 11160|||OZ-277|||OZ
Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.
价 格:¥电议型 号:T26660产 地:中国大陆
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T2663GTS-21 dihydrochloride;化合物GTS 21 dihydrochlorideGTS 21 dihydrochloride|||DMXB-A|||DMBX-anabaseine;GT
GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.
价 格:¥电议型 号:T2663产 地:中国大陆
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T26182Seladelpar lysine;化合物 T26182MBX-8025 lysine dihydrate|||MBX-8025 Lysine|||MBX 8025 Lysine MBX8025 Ly
Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).
价 格:¥电议型 号:T26182产 地:中国大陆
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T24129HBX28258;化合物 T24129HBX 28258|||HBX-28258;HBX 28258|||HBX-28258
HBX28258 is a recombinant human USP7 protein inhibitor. In human colon cancer and embryonic kidney cell, it acts by binding the active site through a covalent mechanism and selectively inactivating USP7 protein.
价 格:¥电议型 号:T24129产 地:中国大陆
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T2375BX471;化合物BX-471BX 471|||BX-471|||ZK-811752;BX 471|||BX-471|||ZK-811752
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.
价 格:¥电议型 号:T2375产 地:中国大陆
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T21527HBX 41108;7-氯-9-氧代-9H-茚并[1,2-B]吡嗪-2,3-二甲腈HBX-41108;HBX-41108|||7-氯-9-氧代-9H-茚并[1,2-B]吡嗪-2,3-二甲腈
HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
价 格:¥电议型 号:T21527产 地:中国大陆
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T19869Elocalcitol;化合物 T19869Ro 26-9228|||BXL 628;Ro 26-9228|||BXL 628
Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.
价 格:¥电议型 号:T19869产 地:中国大陆
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T1837BX-912;化合物BX912BX-912
BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC etc.
价 格:¥电议型 号:T1837产 地:中国大陆