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  • T82712Ciwujianoside C4；化合物 Ciwujianoside C4Ciwujianoside C4

    Ciwujianoside C4, a saponin derivative, has been demonstrated to increase pancreatic lipase activity in vitro [1].

    价 格：￥电议型 号：T82712产 地：中国大陆

  • T82230HCoV-OC43-IN-1；化合物 HCoV-OC43-IN-1HCoV-OC43-IN-1

    HCoV-OC43-IN-1 (Compound IV-16) serves as an inhibitor of the coronavirus HCoV-OC43, exhibiting antiviral efficacy with an EC50 of 90 nM. It effectively inhibits the mRNA levels and expression of the viral nucleocapsid protein (NP) [1].

    价 格：￥电议型 号：T82230产 地：中国大陆

  • T80727ZINC49534341；化合物 ZINC49534341ZINC49534341

    ZINC49534341 is a potent MRGPRX2 antagonist, exhibiting a K_i (inhibition constant) of 32 nM [1].

    价 格：￥电议型 号：T80727产 地：中国大陆

  • T79086MC4171；化合物 MC4171MC4171

    MC4171 (compound 34), a selective KAT8 inhibitor (IC50=8.1 ?M), demonstrates moderate antiproliferative activity at micromolar concentrations in various cancer cell lines, such as NSCLC and AML. This property highlights its potential utility in cancer research [1].

    价 格：￥电议型 号：T79086产 地：中国大陆

  • T78722ZINC475239213；化合物 ZINC475239213ZINC475239213

    ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 μM [1].

    价 格：￥电议型 号：T78722产 地：中国大陆

  • T78246Lemzoparlimab；来佐利单抗TJC4|||TJ011133；TJC4|||TJ011133

    Lemzoparlimab (TJ011133; TJC4), a humanized anti-CD47 IgG4 antibody, exhibits potent antitumor activity [1].

    价 格：￥电议型 号：T78246产 地：中国大陆

  • T78156MC4033；化合物 MC4033MC4033

    MC4033 is a selective lysine acetyltransferase 8 (KAT8) inhibitor (IC50: 12.1 μM) with anticancer effects, induces apoptosis, and can be used for the study of non-small cell lung cancer.

    价 格：￥电议型 号：T78156产 地：中国大陆

  • T77951Thalidomide-5-O-C4-NH2 hydrochloride；化合物 Thalidomide-5-O-C4-NH2 hydrochlorideThalidomide-5-O-C4-NH2

    Thalidomide-5-O-C4-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It can be tethered to a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].

    价 格：￥电议型 号：T77951产 地：中国大陆

  • T7759Thalidomide-O-amido-C4-NH2 TFA；化合物T7759E3 ligase Ligand-Linker Conjugates 19 TFA|||Cereblon Ligand-L

    Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized E3 ligase ligand-linker conjugate.

    价 格：￥电议型 号：T7759产 地：中国大陆

  • T76713Inebilizumab；伊奈利珠单抗MEDI 551|||MT-0551|||16C4-aFuc|||VIB-0551；MEDI 551|||MT-0551|||16C4-aFuc|||VIB-05

    Inebilizumab is a humanized anti-CD19 monoclonal antibody with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used to treat a range of autoimmune diseases associated with CD19 B cells, such as multiple sclerosis and optic neuromyelitis.

    价 格：￥电议型 号：T76713产 地：中国大陆

  • T74730SPC4061；化合物 SPC4061SPC4061

    SPC4061, a potent PCSK9 inhibitor and an antisense nucleotide, specifically targets the lock-in nucleic acid (LNA) of PCSK9. This action is relevant for researching hypercholesterolemia and associated diseases [1] [2].

    价 格：￥电议型 号：T74730产 地：中国大陆

  • T73903UNC4976 TFA；化合物 UNC4976 TFAUNC4976 TFA

    UNC4976 TFA, a positive allosteric modulator (PAM) peptidomimetic of the CBX7 chromodomain, promotes binding to nucleic acids. It concurrently inhibits the H3K27me3-specific recruitment of CBX7 to target genes and enhances non-specific interaction with DNA and RNA [1].

    价 格：￥电议型 号：T73903产 地：中国大陆

  • T73849KDM5-C49 hydrochloride；化合物 KDM5-C49 hydrochlorideKDM5-C49 hydrochloride

    KDM5-C49 (KDOAM-20) hydrochloride is a potent, selective inhibitor of the KDM5 family of demethylases, demonstrating IC50 values of 40 nM for KDM5A, 160 nM for KDM5B, and 100 nM for KDM5C, respectively. This compound is utilized in cancer research [1].

    价 格：￥电议型 号：T73849产 地：中国大陆

  • T73484MC4343；化合物 MC4343MC4343

    MC4343, a potent dual inhibitor targeting both EZH2 and histone deacetylase, presents promising potential for cancer research applications.

    价 格：￥电议型 号：T73484产 地：中国大陆

  • T72385LDC4297 hydrochloride；化合物 LDC4297 hydrochlorideLDC4297 hydrochloride

    LDC4297 hydrochloride is a selective CDK7 inhibitor, characterized by an IC50 of 0.13 nM, demonstrating potent efficacy against human cytomegalovirus (HCMV) replication with an EC50 of 24.5 nM. It features broad antiviral activities against families such as Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02 to 1.21 μM. This compound is utilized in infection research.

    价 格：￥电议型 号：T72385产 地：中国大陆

  • T70870AC430；化合物 AC430AC430

    AC430 is a potent and specific small molecule inhibitor of janus kinase 2 (JAK2), which has been implicated as a target for therapy in both oncology and autoimmune disease. AC430 is currently being developed by Ambit. In preclinical studies, AC430 has exhibited potency against JAK2 and V617F mutated JAK2 in cell-based models that is at least equivalent to, and in most cases superior to, competing JAK2 inhibitors. In preclinical oncology and autoimmune models, AC430 is well tolerated and has sign

    价 格：￥电议型 号：T70870产 地：中国大陆

  • T70862AMPK Activator SC4；化合物 AMPK Activator SC4AMPK Activator SC4

    SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.

    价 格：￥电议型 号：T70862产 地：中国大陆

  • T69823MC4；化合物 MC4MC4

    MC4 is a first-in-class inhibitor of ribosomal RNA synthesis with antimicrobial activity against Staphylococcus aureus.

    价 格：￥电议型 号：T69823产 地：中国大陆

  • T697994-Me-PDTic；化合物 4-Me-PDTic4-Me-PDTic

    4-Me-PDTic is a potent and selective kappa opioid receptor antagonist.

    价 格：￥电议型 号：T69799产 地：中国大陆

  • T66985TAK 438 xC4H4O4；化合物 TAK 438 xC4H4O4TAK 438 xC4H4O4

    TAK 438 xC4H4O4 is a useful organic compound for research related to life sciences and the catalog number is T66985.

    价 格：￥电议型 号：T66985产 地：中国大陆

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