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T6031GNE-0877GNE-0877,GNE0877,GNE 0877
GNE-0877 is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).
价 格:¥电议型 号:T6031产 地:美洲
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T8522Gnetulin;化合物 T8522Gnetulin
Gnetulin is a natural product of Gnetum, Gnetaceae. The catalog number is T8522 and the CAS number is 152340-24-4. Gnetulin can be used as a reference standard.
价 格:¥电议型 号:T8522产 地:中国大陆
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T8521Gnetin D;化合物 T8521Gnetin D
Gnetin D exhibits significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 ug/mL.
价 格:¥电议型 号:T8521产 地:中国大陆
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T8386Esomeprazole Magnesium trihydrate;埃索美拉唑镁三水合物(S)-Omeprazole magnesium trihydrate;埃索美拉唑镁三水合物|||埃索美拉唑镁(
Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases
价 格:¥电议型 号:T8386产 地:中国大陆
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T82275GNE-235;化合物 GNE-235GNE-235
GNE-235, a selective inhibitor of PBRM1´s second bromodomain, exhibits a dissociation constant (K D) of 0.28 ± 0.02 μM, and can be utilized to assess the cellular function of PBRM1 [1].
价 格:¥电议型 号:T82275产 地:中国大陆
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T82274Gnetuhainin I;化合物 Gnetuhainin IGnetuhainin I
Gnetuhainin I (Compound 5), a lignin sourced from Pouzolzia zeylanica, exhibits potent inhibition of ATP citrate lyase (ACLY) with an IC50 value of 2.63 μM [1].
价 格:¥电议型 号:T82274产 地:中国大陆
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T81692Nelistotug;化合物 NelistotugNelistotug
Nelistotug (GSK 6097608; GSK6097608) is a human IgG1κ monoclonal antibody that specifically targets CD96 [1].
价 格:¥电议型 号:T81692产 地:中国大陆
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T81679Nezutatug;化合物 NezutatugNezutatug
Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].
价 格:¥电议型 号:T81679产 地:中国大陆
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T793116a,17a-Epoxy-4-Pregnen-3,20-Dione;16,17-环氧黄体酮16a,17a-Epoxy-4-Pregnen-3,20-Dione
16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progesterone on reproductive organs, the effects of the hormone on cell growth and development, and the effects of the hormone on the immune system.
价 格:¥电议型 号:T7931产 地:中国大陆
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T78558GNE-7883;化合物 GNE-7883GNE-7883
GNE-7883, a pan-TEAD inhibitor, exhibits anti-cell proliferation effects and mitigates resistance to KRAS G12C inhibitors through the inhibition of YAP/TAZ activation in various preclinical models, potentially aiding in the research of YAP/TAZ-dependent cancers [1].
价 格:¥电议型 号:T78558产 地:中国大陆
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T75656Calcimycin hemimagnesium;化合物 Calcimycin hemimagnesiumCalcimycin hemimagnesium
Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium levels and suppresses the growth of Gram-positive bacteria and certain fungi. Additionally, this compound hinders ATPase activity and uncouples oxidative phosphorylation (OXPHOS) in mammalian cells, ultimately leading to apoptosis [1] [2] [3] [4].
价 格:¥电议型 号:T75656产 地:中国大陆
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T75327Magnesium silicate;化合物 Magnesium silicateMagnesium silicate
Activated Magnesium Silicate, a blend of magnesium oxide (MgO) and silicon dioxide (SiO2), serves multiple roles in healthcare and industrial applications, including as an antacid, antiulcer agent, deodorizer, decolorizer, and antifungal treatment [1].
价 格:¥电议型 号:T75327产 地:中国大陆
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T75325ATP dimagnesium;化合物 ATP dimagnesiumATP dimagnesium
Adenosine 5´-triphosphate (ATP) dimagnesium, a pivotal molecule in energy storage and metabolism, fuels metabolic pumps and acts as a coenzyme within cells. Additionally, it plays a significant role as an endogenous signaling molecule in immunity and inflammation [1] [2].
价 格:¥电议型 号:T75325产 地:中国大陆
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T73372GNE-2256;化合物 GNE-2256GNE-2256
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
价 格:¥电议型 号:T73372产 地:中国大陆
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T72640GNE-7915 tosylate;化合物 GNE-7915 tosylateGNE-7915 tosylate
GNE-7915 tosylate is a potent, selective, and brain-penetrant LRRK2 inhibitor, boasting an IC50 value of 9 nM.
价 格:¥电议型 号:T72640产 地:中国大陆
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T71933GNE-3500;化合物 GNE-3500GNE-3500
GNE-3500 is a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist. Retinoic acid receptor-related orphan receptor C (RORc, RORγ, or NR1F3) is a nuclear receptor that plays a major role in the production of interleukin (IL)-17. Considerable efforts have been directed toward the discovery of selective RORc inverse agonists as potential treatments of inflammatory diseases such as psoriasis and rheumatoid arthritis. GNE-3500 poss
价 格:¥电议型 号:T71933产 地:中国大陆
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T7166GNE-493;化合物GNE-493GNE-493
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR,respectively.
价 格:¥电议型 号:T7166产 地:中国大陆
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T71560Atorvastatin magnesium trihydrate;化合物 Atorvastatin magnesium trihydrateAtorvastatin magnesium trihyd
Atorvastatin magnesium trihydrate is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.
价 格:¥电议型 号:T71560产 地:中国大陆
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T71259GNE-900;化合物GNE-900GNE900|||GNE 900;GNE900|||GNE 900
GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 ?M, respectively.GNE-900 enhances DNA damage and induces apoptosis. GNE-900 has antitumor activity.
价 格:¥电议型 号:T71259产 地:中国大陆