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T63766MrgprX2 antagonist-7；化合物 MrgprX2 antagonist-7MrgprX2 antagonist-7
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.
价 格：￥电议型 号：T63766产 地：中国大陆
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T63549MRGPRX1 agonist 4；化合物 MRGPRX1 agonist 4MRGPRX1 agonist 4
MRGPRX1 agonist 4 is a potent and orally active Mas-related G protein-coupled receptor X1 (MRGPRX1) positive conformation modulator (EC50: 0.1 μM). MRGPRX1 agonist 4 ameliorated the behavioral thermal allergic response in mice, a model of MRGPRX1 neuropathic pain.
价 格：￥电议型 号：T63549产 地：中国大陆
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T63394MrgprX2 antagonist-6；化合物 MrgprX2 antagonist-6MrgprX2 antagonist-6
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.
价 格：￥电议型 号：T63394产 地：中国大陆
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T62918GPR84 antagonist 3；化合物 GPR84 antagonist 3GPR84 antagonist 3
GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a favorable pharmacokinetic profile, suitable for further research and development [1].
价 格：￥电议型 号：T62918产 地：中国大陆
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T62858hGPR91 antagonist 3；hGPR91拮抗剂3hGPR91 antagonist 3
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be effective in the treatment of hypertension, autoimmune disease, and retinal angiogenesis.
价 格：￥电议型 号：T62858产 地：中国大陆
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T62656GPR81 agonist 1；GPR81激动剂1GPR81 agonist 1
GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic control in mouse models of insulin resistance and diabetes, and can be used in the study of diabetes and obesity.
价 格：￥电议型 号：T62656产 地：中国大陆
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T62542GPR40 agonist 5；化合物 GPR40 agonist 5GPR40 agonist 5
GPR40 agonist 5 is an orally active GPR40 (G protein-coupled receptor 40) agonist (EC50: 47 nM). gPR40 agonist 5 reduces blood glucose levels and improves glucose tolerance. gPR40 agonist 5 shows adequate control of hyperglycemic state in type 2 diabetic mice.
价 格：￥电议型 号：T62542产 地：中国大陆
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T62420P2Y2R/GPR17 antagonist 1；P2Y2R/GPR17拮抗剂1P2Y2R/GPR17 antagonist 1
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: 1.67 μM) antagonist.
价 格：￥电议型 号：T62420产 地：中国大陆
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T62261GPR84 antagonist 1；化合物 GPR84 antagonist 1GPR84 antagonist 1
GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.
价 格：￥电议型 号：T62261产 地：中国大陆
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T62173GPR41 agonist-1；化合物 GPR41 agonist-1GPR41 agonist-1
GPR41 agonist-1 (compound 9) is a potent agonist of GPR41 and can be used in studies of insulin-related diseases.
价 格：￥电议型 号：T62173产 地：中国大陆
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T61332MRGPRX4 modulator-1；化合物 MRGPRX4 modulator-1MRGPRX4 modulator-1
MRGPRX4 modulator-1 (compound 31-2) is a potent antagonist of the mas-related g-protein receptor X4 (MRGPR X4) with an IC50 < 100 nM against MRGPR4. It is utilized for the investigation of MRGPR X4 dependent diseases including itch, pain, and autoimmune disorders [1].
价 格：￥电议型 号：T61332产 地：中国大陆
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T61183MRGPRX4 modulator-2；化合物 MRGPRX4 modulator-2MRGPRX4 modulator-2
MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson´s Syndrome, and various chronic itch conditions is notable [1].
价 格：￥电议型 号：T61183产 地：中国大陆
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T61055GPR40 agonist 6；化合物 GPR40 agonist 6GPR40 agonist 6
GPR40 agonist 6 (Compound 7a) is a potent and selective agonist of free fatty acid receptor 1 ( FFAR1 or GPR40 ) with an EC 50 of 0.058 μM against GPR40 [1].
价 格：￥电议型 号：T61055产 地：中国大陆
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T60497MRGPRX1 agonist 3；化合物 MRGPRX1 agonist 3MRGPRX1 agonist 3
MRGPRX1 agonist 3 (compound 1f) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC50 of 0.22 μM. MRGPRX1 agonist 3 can be used for neuropathic pain research[1].
价 格：￥电议型 号：T60497产 地：中国大陆
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T60466MRGPRX1 agonist 2；化合物 MRGPRX1 agonist 2MRGPRX1 agonist 2
MRGPRX1 agonist 2 (compound 1a) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC 50 value of 0.48 μM. MRGPRX1 agonist 2 has the potential to be used in neuropathic pain research [1].
价 格：￥电议型 号：T60466产 地：中国大陆
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T4648TC-G-1008；化合物TC-G-1008GPR39-C3；GPR39-C3
TC-G-1008 (GPR39-C3) is a GPR39 (zinc receptor) agonist (EC50 values are 0.4 and 0.8 nM for rat and human receptors respectively).
价 格：￥电议型 号：T4648产 地：中国大陆
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T4312GPR120 Agonist 2；化合物GPR120 receptor agonistGPR120 receptor agonist；GPR120 receptor agonist
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist.
价 格：￥电议型 号：T4312产 地：中国大陆
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T40517GPR30 agonist-1GPR30 agonist-1GPR30 agonist-1
GPR30 agonist-1 is a compound that acts as an agonist for G protein-coupled receptor 30 (GPR30), inducing vasorelaxation.
价 格：￥电议型 号：T40517产 地：中国大陆
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T40273MrgprX2 antagonist-2MrgprX2 antagonist-2MrgprX2 antagonist-2
MrgprX2 antagonist-2 is a potent antagonist of MrgprX2. It holds potential for investigating skin inflammatory disorders.
价 格：￥电议型 号：T40273产 地：中国大陆
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T40271MrgprX2 antagonist-3MrgprX2 antagonist-3MrgprX2 antagonist-3
MrgprX2 antagonist-3 is a potent inhibitor of MrgprX2. It holds promising potential for investigating skin inflammatory disorders.
价 格：￥电议型 号：T40271产 地：中国大陆
