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T60554Schnurri-3 inhibitor-1;化合物Schnurri-3抑制剂-1Schnurri-3 inhibitor-1
Schnurri-3 inhibitor-1 is a potent inhibitor of schnurri-3, an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in Shn3FFL (osteoblast cell line, AC50= 2.09 μM). Schnurri-3 inhibitor-1 has research value in osteoporosis.
价 格:¥电议型 号:T60554产 地:中国大陆
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T60317α-HNJNAc;化合物 α-HNJNAcα-HNJNAc
α-HNJNAc is a potent, competitive hexosaminidases inhibitor that does not interfer with other glycosidases [1].
价 格:¥电议型 号:T60317产 地:中国大陆
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T5916Fmoc-N-Me-Phe-OHN-(9-芴甲氧羰酰基)-N-甲基-L-苯丙氨酸N-(9-芴甲氧羰酰基)-N-甲基-L-苯丙氨酸|||Fmoc-N-methyl-L-phenylalanine
Fmoc-N-Me-Phe-OH (Fmoc-N-methyl-L-phenylalanine) is a Malaria Parasite inhibitor.
价 格:¥电议型 号:T5916产 地:中国大陆
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T51562,3,2’’,3’’-Tetrahydroochnaflavone化合物 T5156金银花
2,3,2´´,3´´-Tetrahydroochnaflavone is a natural product of Lonicera, Caprifoliaceae. The catalog number is T5156 and the CAS number is 678138-59-5. 2,3,2´´,3´´-Tetrahydroochnaflavone can be used as a reference standard.
价 格:¥电议型 号:T5156产 地:中国大陆
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T4S1335Daphnoretin;西瑞香素Dephnoretin|||Thymelol;Dephnoretin|||西瑞香素|||Thymelol
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. 3. Daphnoretin causes death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.
价 格:¥电议型 号:T4S1335产 地:中国大陆
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T4192hnps-PLA Inhibitor;化合物hnps-PLA Inhibitorhnps-PLA Inhibitor
Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
价 格:¥电议型 号:T4192产 地:中国大陆
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T41135Defensin HNP-1 human;Defensin HNP-1 humanDefensin HNP-1 human
Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development.Defensin HNP-1 human can regulate the growth of atherosclerosis.
价 格:¥电议型 号:T41135产 地:中国大陆
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T41134Defensin HNP-2 human;Defensin HNP-2 humanDefensin HNP-2 human
Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.
价 格:¥电议型 号:T41134产 地:中国大陆
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T40516Nonylbenzene-PEG8-OH;Nonylbenzene-PEG8-OHNonylbenzene-PEG8-OH;Nonylbenzene-PEG8-OH
Nonylbenzene-PEG8-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40516产 地:中国大陆
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T39462Nonylbenzene-PEG5-OH;Nonylbenzene-PEG5-OHNonylbenzene-PEG5-OH;Nonylbenzene-PEG5-OH
Nonylbenzene-PEG5-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39462产 地:中国大陆
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T39429AHN 1-055 hydrochloride;化合物AHN 1-055 hydrochloride3α-Bis-(4-fluorophenyl) Methoxytropane hydrochlori
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).
价 格:¥电议型 号:T39429产 地:中国大陆
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T38103Defensin HNP-3 (human) (trifluoroacetate salt);Defensin HNP-3 (human) (trifluoroacetate salt)Defensi
Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd
价 格:¥电议型 号:T38103产 地:中国大陆
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T37036hnRNPK-IN-1;hnRNPK-IN-1hnRNPK-IN-1
hnRNPK-IN-1 is a specific ligand that binds to the heterogeneous nuclear ribonucleoprotein K (hnRNPK) with high affinity, evidenced by Kd values of 4.6 μM and 2.6 μM determined using surface plasmon resonance (SPR) and microscale thermophoresis (MST), respectively. This binding event leads to the disruption of hnRNPK´s interaction with the c-myc promoter, resulting in the inhibition of c-myc transcription. Additionally, hnRNPK-IN-1 induces apoptosis in Hela cells and exhibits potent anti-t
价 格:¥电议型 号:T37036产 地:中国大陆
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T36260NR 7h;NR 7hNR 7h
Potent and selective p38α and p38β degrader (DC50 < 50 nM). Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2. Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-derived macrophages (BMDM). Exhibits similar effect to p38α gene knockout in BBL358 cells. Active in vivo.
价 格:¥电议型 号:T36260产 地:中国大陆
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T3616Carbazochrome卡巴克络AC-17|||Adrenostazin|||Cromadrenal|||Adona|||Adchnon|||卡巴克络|||Adedolon
Carbazochrome (Adchnon) is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on its effectiveness and the severity of possible side effects remains to be fairly inconclusive. Carbazochrome
价 格:¥电议型 号:T3616产 地:中国大陆
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T36108YW3-56 (hydrochloride) (technical grade);YW3-56 (hydrochloride) (technical grade)YW3-56 (hydrochlori
YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 μM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 μM) in a p53-dependent mannerviainduction of SESN2 and subsequent inhibition of mTORC1. YW3-56 (10 mg/kg) reduces tumor growth in an S-180 murine sarcoma tumor model. It also inhibits tumor growth in the 1883 MDA-MB-231 breast cancer bone metastasis mouse xenograft model.2
价 格:¥电议型 号:T36108产 地:中国大陆
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T3504AZD5153 6-Hydroxy-2-naphthoic acid;AZD5153结晶体(API形式)AZD5153|||AZD-5153 HNT salt;AZD5153|||AZD5153结晶体
AZD5153 6-Hydroxy-2-naphthoic acid (AZD5153) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatments.
价 格:¥电议型 号:T3504产 地:中国大陆
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T33159Macrodaphnidin;化合物 T33159NSC 299118|||YUZURIMINE|||NSC299118|||NSC-299118;NSC 299118|||YUZURIMINE|||
Macrodaphnidin is a biochemical.
价 格:¥电议型 号:T33159产 地:中国大陆
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T33021Lychnopholide;化合物 T33021Lychnopholide
Lychnopholide is isolated from Vanillosmopsis erythropappa.
价 格:¥电议型 号:T33021产 地:中国大陆
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T32837Lochneridine;化合物 T32837Lochneridine
Lochneridine is a bioactive chemical.
价 格:¥电议型 号:T32837产 地:中国大陆