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T81970Kuwanon T;化合物 Kuwanon TKuwanon T
Kuwanon T, an isoprenylated flavonoid extracted from the root bark of Morus alba, exhibits protective effects against t-BHP-induced oxidative stress, presenting an EC50 value of 30.32 μM [1].
价 格:¥电议型 号:T81970产 地:中国大陆
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T81969Kuwanon W;化合物 Kuwanon WKuwanon W
Kuwanon W, a natural product, is isolable from the root bark of Morus lhou [1].
价 格:¥电议型 号:T81969产 地:中国大陆
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T81809Methylkushenol C;化合物 Methylkushenol CMethylkushenol C
Methylkushenol C, a phenolic compound, can be isolated from Sophora flavescens [1].
价 格:¥电议型 号:T81809产 地:中国大陆
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T80599Dectrekumab;德屈库单抗QAX576;QAX576
Dectrekumab (QAX576), a humanized monoclonal antibody targeting IL-13, significantly reduces intraepithelial esophageal eosinophil counts and normalizes dysregulated esophageal disease-related transcripts in Eosinophilic esophagitis (EoE), offering sustained benefits. It is valuable for inflammation and immunology research [1].
价 格:¥电议型 号:T80599产 地:中国大陆
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T80496Kurtoxin;化合物 KurtoxinKurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type) Ca2+ channel. The compound demonstrates high-affinity interactions with native neuronal high-threshold L-type, N-type, and P-type Ca2+ channels in both central and peripheral neurons, while also displaying cross-reactivity with the voltage-gated Na+ channel [1].
价 格:¥电议型 号:T80496产 地:中国大陆
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T76934Brazikumab;化合物 BrazikumabBrazikumab
Brazikumab (AMG 139), a human IgG2 monoclonal antibody, selectively targets the p19 subunit of IL-23 with a dissociation constant (K D) of 0.138 nM, indicating high affinity for human IL-23. It is employed in Crohn´s disease research [1].
价 格:¥电议型 号:T76934产 地:中国大陆
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T76901Afasevikumab;化合物 AfasevikumabAfasevikumab
Afasevikumab (RG 7624; RO 5553110; NI-1401), a fully human monoclonal IgG1κ antibody, neutralizes both IL-17A and IL-17F, exhibiting anti-inflammatory activities [1].
价 格:¥电议型 号:T76901产 地:中国大陆
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T76826Sirukumab;化合物 SirukumabSirukumab
Sirukumab (CNTO-136), a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody, holds potential for research in active lupus nephritis [1].
价 格:¥电议型 号:T76826产 地:中国大陆
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T76747Fletikumab;夫来库单抗Anti-IL-20|||NN-8226|||NNC 0109-0012;Anti-IL-20|||NN-8226|||NNC 0109-0012
Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis and psoriasis.
价 格:¥电议型 号:T76747产 地:中国大陆
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T73069Kurzipene D;化合物 Kurzipene DKurzipene D
Kurzipene D, a potent anticancer agent, induces apoptosis and arrests the HepG2 cell cycle at the S stage. Demonstrating anti-tumor effects in an in vivo zebrafish model, Kurzipene D inhibits tumor proliferation and migration.
价 格:¥电议型 号:T73069产 地:中国大陆
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T73061Amakusamine;化合物 AmakusamineAmakusamine
Amakusamine effectively suppresses the formation of multinuclear osteocasts triggered by the receptor activator of nuclear factor-κB ligand (RANKL) with an inhibitory concentration (IC50) of 10.5 μM in RAW264.7 cells.
价 格:¥电议型 号:T73061产 地:中国大陆
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T72289Type II TRKu00A0inhibitor 1;化合物 Type II TRKu00A0inhibitor 1Type II TRKu00A0inhibitor 1
Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) fusion protein variants as well as the wild type. It demonstrates notable antiproliferative effects on Ba/F3 cells expressing CD74-TRKA G667C and ETV6-TRKC G696C, with half-maximal inhibitory concentrations (IC50s) of 6 nM and 1.7 nM, respectively [1].
价 格:¥电议型 号:T72289产 地:中国大陆
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T71909Kumbicin C;化合物 Kumbicin CKumbicin C
Kumbicin C inhibits the growth of NS-1 mouse myeloma cells (IC50 = 0.74 μg/ml) and the growth of the Gram-positive bacteria B. subtilis (MIC = 1.6 μg/ml).
价 格:¥电议型 号:T71909产 地:中国大陆
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T7026LKukoamine B mesylate;地骨皮乙素 甲磺酸盐KukoamineBmesylate|||KukoamineBmesylate;KukoamineBmesylate|||Kukoamin
Kukoamine B mesylate is a novel cationic alkaloid derived from dermatophytes with antioxidant activity, inhibits LPS internalization in Kupffer and RAW 264.7 cells, and can be used to study acute inflammation and diabetes.
价 格:¥电议型 号:T7026L产 地:中国大陆
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T7026KukoaMine B;地骨皮乙素KukoaMine B
Kukoamine B, as a constituent of Lycii Cortex, exhibits anti-acute inflammatory, anti-oxidant, and anti-diabetic characteristics.
价 格:¥电议型 号:T7026产 地:中国大陆
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T69779KUNB31;化合物 KUNB31KUNB31
KUNB31 is a potent and selective inhibitor of Hsp90β.
价 格:¥电议型 号:T69779产 地:中国大陆
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T68978KU-0058684;化合物 KU-0058684KU-0058684
KU-0058684 is a potent PARP and DNA-PK inhibitors.
价 格:¥电议型 号:T68978产 地:中国大陆
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T68736KU-0058948;化合物 KU-0058948KU-0058948
KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor that induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro.
价 格:¥电议型 号:T68736产 地:中国大陆
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T6557KU-0060648;化合物KU0060648KU0060648;KU0060648
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
价 格:¥电议型 号:T6557产 地:中国大陆
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T64311KUSC-5037;化合物 KUSC-5037KUSC-5037
KUSC-5037 is a potent inhibitor of HIF-1 with an IC50 value of 1.2 μM. KUSC-5037 exhibits inhibitory effects on mitochondrial respiratory complex V and FoF1ATP synthase.
价 格:¥电议型 号:T64311产 地:中国大陆