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T83863Fluostatin A sodium;化合物 Fluostatin A sodiumFluostatin A sodium
Fluostatin A, a fluorenone compound initially isolated from Streptomyces, demonstrates selective inhibition towards dipeptidyl peptidase 3 (DPP-3) compared to DPP-1, DPP-2, and DPP-4 with IC50 values of 0.44 ?g/ml for DPP-3 and over 100 ?g/ml for the others, respectively.
价 格:¥电议型 号:T83863产 地:中国大陆
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T8334CADD522;化合物CADD522MFCD00167693;MFCD00167693|||3-{[(3,4-二氯苯基)氨基]羰基}二环[2.2.1]庚-5-烯-2-羧酸
CADD522 (MFCD00167693) is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity
价 格:¥电议型 号:T8334产 地:中国大陆
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T82922BAPTA-TMFM;化合物 BAPTA-TMFMBAPTA-TMFM
BAPTA-TMFM is a fluorescent chelator employed to investigate cytosolic free calcium´s function.
价 格:¥电议型 号:T82922产 地:中国大陆
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T82900Bemfivastatin hemicalcium;化合物 Bemfivastatin hemicalciumPPD 10558 hemicalcium;PPD 10558 hemicalcium
Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent. It amplifies liver extract activity and exhibits no-observed adverse effect levels (NOAEL) at dosages of ≥320 mg/kg/d for rat developmental toxicity, ≥12.5 mg/kg/d for rabbit maternal toxicity, and ≥25 mg/kg/d for rabbit developmental toxicity. This compound is utilized in research concerning hypercholesterolemic myalgia in patients intolerant to statins.
价 格:¥电议型 号:T82900产 地:中国大陆
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T82475Emfilermin;化合物 EmfilerminEmfilermin
Emfilermin, a recombinant human leukemia inhibitory factor (LIF), is utilized in the research of chemotherapy-induced peripheral neuropathy [1].
价 格:¥电议型 号:T82475产 地:中国大陆
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T82385FMF-06-098-1;化合物 FMF-06-098-1FMF-06-098-1
FMF-06-098-1 is a multitargeted depressant capable of promoting the degradation of a wide array of kinases, including AAK1, ABL2, AURKA, AURKB, BUB1B, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDK6, CDK7, CDK9, CHEK1, CSNK1D, EPHA1, PAK, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, SGK2, STK35, TNK2, UHMK1, ULK1, and WEE1 [1].
价 格:¥电议型 号:T82385产 地:中国大陆
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T81968KY-1044;化合物 KY-1044SAR 445256|||Alomfilimab;SAR 445256|||Alomfilimab
KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 monoclonal antibody that targets the inducible costimulatory receptor (ICOS). This compound selectively depletes cells with high ICOS expression through antibody-dependent cellular cytotoxicity (ADCC), mediated by FcγRIIIa engagement. Meanwhile, it acts as a costimulatory molecule for cells with lower ICOS levels, such as CD8+ T Effector cells, via FcγR-dependent clustering. KY-1044 leverages varying ICOS expression levels across T-cell sub
价 格:¥电议型 号:T81968产 地:中国大陆
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T81803MFN2 agonist-1;化合物 MFN2 agonist-1MFN2 agonist-1
MFN2 agonist-1 (B-A/l) effectively induces mitochondrial fusion in cells deficient in mitofusin 2 (MFN2). It counteracts mitochondrial "clumping" (formation of static mitochondrial aggregates) and reinstates mitochondrial movement in cultured mouse neurons harboring the CMT2A-associated MFN2 T105M mutation.
价 格:¥电议型 号:T81803产 地:中国大陆
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T81765Monofucosyllacto-N-hexaose I;化合物 Monofucosyllacto-N-hexaose IMFLNH I;MFLNH I
Monofucosyllacto-N-hexaose I (MFLNH I) constitutes a human milk oligosaccharide (HMO) [1].
价 格:¥电议型 号:T81765产 地:中国大陆
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T81764Monofucosyllacto-N-hexaose III;化合物 Monofucosyllacto-N-hexaose IIIMFLNH III;MFLNH III
Monofucosyllacto-N-hexaose III (MFLNH III) is a neutral human milk oligosaccharide (HMO) [1].
价 格:¥电议型 号:T81764产 地:中国大陆
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T81224SALMF amide 2;化合物 SALMF amide 2SALMF amide 2
SALMFamide 2, a neuropeptide S2 derived from the starfish Asterias rubens, plays a regulatory role in the eversion of the cardiac stomach in starfish [1].
价 格:¥电议型 号:T81224产 地:中国大陆
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T80584Anti-Mouse Fas Ligand Antibody (MFL3);化合物 Anti-Mouse Fas Ligand Antibody (MFL3)Anti-Mouse Fas Ligand
Anti-Mouse Fas Ligand Antibody is an Armenian hamster-derived IgG inhibitor that targets the mouse Fas Ligand.
价 格:¥电议型 号:T80584产 地:中国大陆
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T796033,7-DMF;化合物 3,7-DMF3,7-DMF
3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation. By inducing antioxidant gene expression and scavenging reactive oxygen species (ROS), 3,7-DMF is useful for researching liver fibrosis [1].
价 格:¥电议型 号:T79603产 地:中国大陆
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T79369ZMF-23;化合物 ZMF-23ZMF-23
ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-α-regulated necroptosis and augmenting apoptosis. The compound effectively hampers the Warburg effect and cell motility, positioning it as a potential research tool for triple-negative breast cancer (TNBC) [1].
价 格:¥电议型 号:T79369产 地:中国大陆
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T79002FITC-labeled ODN TTAGGG sodium;化合物 FITC-labeled ODN TTAGGG sodiumFITC-labeled ODN TTAGGG sodium
FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS. This compound facilitates the assessment of CpG ODN cellular uptake and localization via confocal laser-scanning microscopy (excitation at 495 nm, emission at 520 nm) or flow cytometry.
价 格:¥电议型 号:T79002产 地:中国大陆
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T79000FITC-labeled ODN 2395 sodium;化合物 FITC-labeled ODN 2395 sodiumFITC-labeled ODN 2395 sodium
FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
价 格:¥电议型 号:T79000产 地:中国大陆
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T78998FITC-labeled ODN 2216 sodium;化合物 FITC-labeled ODN 2216 sodiumFITC-labeled ODN 2216 sodium
FITC-labeled ODN 2216 (sodium), a specific agonist for human toll-like receptor 9 (TLR9), facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
价 格:¥电议型 号:T78998产 地:中国大陆
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T78996FITC-labeled ODN 2088 sodium;化合物 FITC-labeled ODN 2088 sodiumFITC-labeled ODN 2088 sodium
FITC-labeled ODN 2088 (sodium) serves as a potent inhibitor of TLR3, TLR7, and TLR9, and is utilized to assess CpG ODN cellular uptake and localization utilizing confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
价 格:¥电议型 号:T78996产 地:中国大陆
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T78994FITC-labeled ODN 1668 sodium;化合物 FITC-labeled ODN 1668 sodiumFITC-labeled ODN 1668 sodium
FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist. This compound is utilized to assess the cellular uptake and localization of CpG ODNs using techniques such as confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) and flow cytometry.
价 格:¥电议型 号:T78994产 地:中国大陆
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T78992FITC-labeled ODN 1585 sodium;化合物 FITC-labeled ODN 1585 sodiumFITC-labeled ODN 1585 sodium
FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production and serves to assess CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
价 格:¥电议型 号:T78992产 地:中国大陆