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产品数:86101
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TQ0027Transcrocetinate disodiumiGluR,Transcrocetinate disodium,Inhibitor,inhibit,Ionotropic glutamate rece
Transcrocetinate disodium, extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor.
价 格:¥电议型 号:TQ0027产 地:中国大陆
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T8638NPC 15199NSC334290,NPC-15199,NPC 15199,NPC15199,Fmoc-leucine,inhibit,Inhibitor,NSC 334290,Peroxisome
NPC 15199 is an anti-inflammatory agent.
价 格:¥电议型 号:T8638产 地:中国大陆
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T6911NSC-87877 disodiumApoptosis,Neuroblastoma,inhibit,Inhibitor,NSC 87877 disodium,PPAR,p53,Phosphatase,
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格:¥电议型 号:T6911产 地:中国大陆
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T8732CTPI-2macrophage,carrier,CTPI-2,NSCLC,transporter,glucose,steatohepatitis,CTPI 2,Mitochondrial Metab
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
价 格:¥电议型 号:T8732产 地:中国大陆
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T7691NSC 3852NSC 3852
NSC 3852 is a potent inhibitor of histone deacetylase.
价 格:¥电议型 号:T7691产 地:中国大陆
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T9929RamucirumabRamucirumab,NSCLC,non–small-cell lung cancer,gastric cancer,Inhibitor,VEGFR,Vascular endo
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
价 格:¥电议型 号:T9929产 地:中国大陆
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T7525DidoxInhibitor,DNA/RNA Synthesis,inhibit,Didox,NSC 324360,NSC324360
Didox is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia.
价 格:¥电议型 号:T7525产 地:中国大陆
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T8656CAY10404Bcl-XL,CAY10404,cancer,COX,anti-inflammatory,Bcl-2,Apoptosis,Akt,H-1703,Cyclooxygenase,NSCLC
CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSCLC cells, with analgesic, anti-inflammatory and anti-cancer activities.
价 格:¥电议型 号:T8656产 地:中国大陆
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T6455CP-91149diabetes,CP91149,CP-91149,A549,CP 91149,NSCLC,Inhibitor,inhibit
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
价 格:¥电议型 号:T6455产 地:中国大陆
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T60078NSC2805
NSC2805 is an inhibitor of WWP2, an E3 ubiquitin ligase with an IC50 of 0.38 μM. NSC2805 can be used in anticancer studies.
价 格:¥电议型 号:T60078产 地:中国大陆
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T7078NSC 95397Apoptosis,NSC-95397,Inhibitor,NSC 95397,inhibit,NSC95397,Phosphatase
NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).
价 格:¥电议型 号:T7078产 地:中国大陆
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TQ0196Cucurbitacin IJanus kinase,JAK,NSC521777,Inhibitor,JSI 124,JSI124,Cucurbitacin I,STAT,NSC 521777,inh
Cucurbitacin I, a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.
价 格:¥电议型 号:TQ0196产 地:中国大陆
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T9398NSC 731506 methyl 2 [2 [(E) (6 oxo 1 cyclohexa 2,4 dienylidene)methyl]hydraziny l] 1H pyrimidin 4 on
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one
价 格:¥电议型 号:T9398产 地:中国大陆
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T6519GramineGramine,Adrenergic Receptor,AdipoRs,Reverse Transcriptase,Inhibitor,Adiponectin Receptor,Beta
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine has anti-tumor, anti-viral and anti-inflammatory properties.
价 格:¥电议型 号:T6519产 地:中国大陆
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T9605Sangivamycincells,Nucleoside Antimetabolite/Analog,Sangivamycin,antitumor,NSC-65346,PKC,MCF7,NSC6534
Sangivamycin is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.
价 格:¥电议型 号:T9605产 地:中国大陆
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T6611NSC697923
NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity.
价 格:¥电议型 号:T6611产 地:中国大陆
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T6910NSC59984NSC-59984,inhibit,Inhibitor,NSC59984,MDM-2/p53,NSC 59984
NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.
价 格:¥电议型 号:T6910产 地:中国大陆
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T6343GeldanamycinNSC 122750;格尔德霉素
Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
价 格:¥电议型 号:T6343产 地:中国大陆
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T6342NSC 23766 trihydrochlorideNSC 23766;Rac1 Inhibitor
NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
价 格:¥电议型 号:T6342产 地:中国大陆
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T6336AmonafideNafidimide;Quinamed;AS1413;NSC308847,AS1413;氨萘非特
Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
价 格:¥电议型 号:T6336产 地:中国大陆