T9902AtezolizumabAtezolizumab,Inhibitor,MPDL3280A,inhibit,Apoptosis,Autophagy

Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.

价 格：￥电议型 号：T9902产 地：中国大陆

T8384Gatifloxacin hydrochlorideAM-1155,Antibiotic,PD 135432,BMS 206584,E. coli,?Pseudomonas aeruginosa,?M

Gatifloxacin hydrochloride is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.

价 格：￥电议型 号：T8384产 地：中国大陆

T19783DehydroabiethylaminePyruvate dehydrogenase kinase,PDH kinase,Dehydroabiethylamine,Inhibitor,PDHK,Can

Dehydroabiethylamine is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.

价 格：￥电议型 号：T19783产 地：中国大陆

T8647BCH001PARN,dyskeratosis,telomerase,stem,BCH 001,polynucleotide,TERC,rPAPD5,ncRNA,BCH001,polymerases,

BCH001 is a specific small-molecule inhibitor of PAPD5.

价 格：￥电议型 号：T8647产 地：中国大陆

T7542Amino TadalafilPhosphodiesterase (PDE),Inhibitor,Amino Tadalafil,inhibit

Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.

价 格：￥电议型 号：T7542产 地：中国大陆

PDK0255Compound PDK0255Compound PDK0255

价 格：￥电议型 号：PDK0255产 地：中国大陆

T9499Icenticaftorinhibit,Icenticaftor,COPD,CFTR,QBW 251,cystic,Inhibitor,G551D,Cystic fibrosis transmembr

Icenticaftor is an orally active potentiator of?CFTR channel.

价 格：￥电议型 号：T9499产 地：中国大陆

T7530PD146176inhibit,tau,brain,triple,NSC-168807,PD146176,Autophagy,pathology,amyloidosis,transgenic,reti

PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.

价 格：￥电议型 号：T7530产 地：中国大陆

T39341FCPR03antidepressant-like,FCPR-03,PDE4B1,FCPR 03,PDE4D7,PDE4,neuroprotective,ischemic,FCPR03,AKT,GSK

FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepressant-like effects.

价 格：￥电议型 号：T39341产 地：中国大陆

TN2159Robustinealkaloid,phosphodiesterase,Phosphodiesterase (PDE),Robustine,PDE5A,inhibit,Inhibitor

Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.

价 格：￥电议型 号：TN2159产 地：中国大陆

T8462Enoximoneinhibit,Enoximone,bronchodilatory,CD11b,eosinophils,vasodilating,Phosphodiesterase (PDE),ai

Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.

价 格：￥电议型 号：T8462产 地：中国大陆

TP2036LDPDPE TFA (88373-73-3 free base)DOR,Inhibitor,DPDPE,inhibit,DPDPE TFA (88373733 free base),anticonvu

DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.

价 格：￥电议型 号：TP2036L产 地：中国大陆

T8527CPYPPDOCK2,CPYPP,Inhibitor,GEF,Rac1,DOCK180,lymphocytes,autoimmune,DOCK2-Rac1,inhibit,DOCK5,immunosu

CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 μM). CPYPP also inhibits DOCK180, DOCK5 and less DOCK9

价 格：￥电议型 号：T8527产 地：中国大陆

T12383PD 168568 dihydrochloride

PD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).

价 格：￥电议型 号：T12383产 地：中国大陆

T0096VardenafilPhosphodiesterase (PDE),erectile dysfunction,stimulation,diabetes,Zucker diabetic fatty (Z

Vardenafil (Levitra) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate c

价 格：￥电议型 号：T0096产 地：中国大陆

T7104Dovitinib lactateFGFR,CHIR-258,Dovitinib,c-Kit,SCFR,PDGFR,CD117,Platelet-derived growth factor recep

Dovitinib lactate(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).

价 格：￥电议型 号：T7104产 地：中国大陆

T8496MAZ51EGFR,Apoptosis,growth,phosphorylation,Inhibitor,inhibit,PDGFRβ,MAZ51,MAZ 51,tumor,VEGF-D,indoli

MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.

价 格：￥电议型 号：T8496产 地：中国大陆

PDK0430L-CyclopentylglycineLCyclopentylglycine

价 格：￥电议型 号：PDK0430产 地：中国大陆

TN1355Acanthoside BCOPD,Acanthoside B,Alzheimer’s disease,inhibit,chronic obstructive pulmonary disease,An

Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer´s disease and lung inflammation.

价 格：￥电议型 号：TN1355产 地：中国大陆

T8544Masitinib mesylateSCFR,PDGFR,c-Kit,Apoptosis,AB 1010,Src,CD117,Masitinib,Platelet-derived growth fac

Masitinib mesylate is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;PDGFRα/β;LynB,respectively).

价 格：￥电议型 号：T8544产 地：中国大陆