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T81993Kadsurin A analogue-1;化合物 Kadsurin A analogue-1Kadsurin A analogue-1
Kadsurin A Analogue-1 (Compound 8), a lignan, can be extracted from Piper argyrophylum [1].
价 格:¥电议型 号:T81993产 地:中国大陆
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T81825Melan-A/MART-1 analog;化合物 Melan-A/MART-1 analog[Leu27]-Melan-A, MART-1 (26-35);[Leu27]-Melan-A, MART
[Leu27]-Melan-A, MART-1 (26-35), is a biologically active peptide modified by substituting leucine for alanine at position 27, which enhances its HLA-A*0201 binding, immunogenicity, and antigenicity compared to the natural peptide. Pyroglutamyl (pGlu) peptides, arising from the spontaneous cyclization of glutamine (Q) or glutamic acid (E) at the N-terminus, are a recognized subset of peptides that may confer increased stability due to the hydrophobic γ-lactam ring of pGlu. These pGlu peptides ar
价 格:¥电议型 号:T81825产 地:中国大陆
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T8055TFEB activator 1;化合物TFEB activator 1(1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,|||Curcumin analog compo
TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer´s disease.
价 格:¥电议型 号:T8055产 地:中国大陆
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T7944VPS34 inhibitor 1 (Compound 19, PIK-III analogue);化合物VPS34PIK-III analogue;PIK-III analogue
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)
价 格:¥电议型 号:T7944产 地:中国大陆
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T78984Xanthine oxidase-IN-10;Xanthine oxidase抑制剂10XO8 analog;XO8 analog
Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.
价 格:¥电议型 号:T78984产 地:中国大陆
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T78571Albiglutide fragment TFA;化合物 Albiglutide fragment TFAGLP-1-Gly8 TFA|||GLP-1 (7-36) analog TFA;GLP-1-
Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as a GLP-1 analog. It functions as a long-acting agonist of the GLP-1 receptor, derived from a fusion of a GLP-1 dimer with the human albumin gene. Clinically, this compound demonstrates a pronounced reduction in glycosylated hemoglobin (A1C) levels, rendering it a valuable therapeutic in type 2 diabetes (T2D) research [1] [2] [3] [4].
价 格:¥电议型 号:T78571产 地:中国大陆
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T77816Deruxtecan analog 2;化合物 Deruxtecan analog 2Deruxtecan analog 2
Deruxtecan Analog 2 (example 9 P3), a Deruxtecan derivative, serves as an agent-linker conjugate integrating Camptothecin (CPT), a Topo I inhibitor active against colorectal, breast, lung, and ovarian cancers, with a distinct linker. This analog is employed in synthesizing anti-FGFR2 ADC [1].
价 格:¥电议型 号:T77816产 地:中国大陆
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T76487Calmodulin Dependent Protein Kinase Substrate Analog;化合物 Calmodulin Dependent Protein Kinase Substra
Calmodulin-Dependent Protein Kinase Substrate Analog, a synthetic peptide substrate, is activated by Ca2+ and calmodulin (CaM). It serves as a substrate for protein kinases, leveraging a dependency on Ca2+ and CaM for its function [1].
价 格:¥电议型 号:T76487产 地:中国大陆
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T74641Rezivertinib analogue 1;化合物 Rezivertinib analogue 1Rezivertinib analogue 1
Rezivertinib analogue 1, a process impurity of osimertinib mesylate, serves as a research tool in the study of non-small cell lung cancer (NSCLC) [1].
价 格:¥电议型 号:T74641产 地:中国大陆
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T71912PD 173955-Analog1;化合物 PD 173955-Analog1PD 173955-Analog1
PD 173955-Analog1 is a potent c-Src inhibitor known to have activity against a variety of cancers including colon, lung, head and neck carcinoma.
价 格:¥电议型 号:T71912产 地:中国大陆
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T70928CB-1158-analog;化合物 CB-1158-analogCB-1158-analog
CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vitro and reduced tumor growth in multiple mouse models of cancer, as a single agent and in combination with checkpoint blockade, adoptive T cell therapy, adoptive NK cell therapy, and the chemotherapy agent gemcitabine. CB-1158 increased tumor-infiltrating CD8+ T cells and NK cell
价 格:¥电议型 号:T70928产 地:中国大陆
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T69967Laropiprant analog;化合物 Laropiprant analogLaropiprant analog
Laropiprant analog is an antagonist of the prostaglandin PGD2 receptor DP1.
价 格:¥电议型 号:T69967产 地:中国大陆
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T6921ONO-4059 analog;化合物ONO-4059 analogueONO-4059 analogue|||ONO-WG-307|||GS-4059 analog;ONO-4059 analogu
ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.
价 格:¥电议型 号:T6921产 地:中国大陆
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T68855Hymenialdisine Analogue #1;化合物 Hymenialdisine Analogue #1Hymenialdisine Analogue #1
Hymenialdisine Analogue #1 is the indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations.
价 格:¥电议型 号:T68855产 地:中国大陆
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T6705TIC10 Isomer;化合物TIC10 IsomerONC201 isomer|||TIC10 Analogue;ONC201 isomer|||TIC10 Analogue
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格:¥电议型 号:T6705产 地:中国大陆
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T65550Gefitinib analog III吉非替尼类似物III4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
Gefitinib analog III(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate) has potential anti-inflammatory and anti-tumor activity and can be used to study its interactions and activity in organisms.
价 格:¥电议型 号:T65550产 地:中国大陆
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T63523Duocarmycin analog-2;化合物 Duocarmycin analog-2Duocarmycin analog-2
Duocarmycin analog-2 is a potent DNA alkylating agent that exhibits antitumor effects and can be used in the synthesis of immunocouplers.
价 格:¥电议型 号:T63523产 地:中国大陆
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T6351MGCD-265 analog;化合物MGCD-265 analogMGCD-265|||Glesatinib;MGCD-265|||Glesatinib
MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.
价 格:¥电议型 号:T6351产 地:中国大陆
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T6266LPP2 Analog;化合物 T6266LPP2-Analog|||CHEMBL-306012|||CHEMBL306012|||CHEMBL 306012;PP2-Analog|||CHEMBL-3
PP2 Analog is an analog of PP2. It also acts as a protein trafficking modulator.
价 格:¥电议型 号:T6266L产 地:中国大陆
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T61970Kolavenic acid analog;化合物 Kolavenic acid analogKolavenic acid analog
Kolavenic acid analog (KAA) is a compound with anticancer activity. Kolavenic acid analog shows potent activity against HSET -overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing supernumerary centrosomes and high HSET levels.
价 格:¥电议型 号:T61970产 地:中国大陆