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T70183Eptapirone fumarate;化合物 Eptapirone fumarateEptapirone fumarate
Eptapirone, also known as F11440, is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone, in exerting 5-HT1A agonist activity at pre- and postsynaptic receptors in rats (measured by, for exam
价 格:¥电议型 号:T70183产 地:中国大陆
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T69938Befiradol fumarate;化合物 Befiradol fumarateBefiradol fumarate
Befiradol fumarate is a highly selective and potent 5-HT1A receptor agonist potentially for the treatment of drug-induced dyskinesia in patients with Parkinson´s disease.
价 格:¥电议型 号:T69938产 地:中国大陆
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T69808ABT-925 fumarate;化合物 ABT-925 fumarateABT-925 fumarate
ABT-925, also known as A-37203, BSF-201640; DAT-201; Lu-201640; and A-437203, is a selective dopamine D3 receptor (DRD3) antagonist with an approximately 100-fold higher in vitro affinity for dopamine D? versus D? receptors. ABT-925 was tested in schizophrenia. ABT-925 is a selective dopamine D? receptor antagonist with an approximately 100-fold higher in vitro affinity for dopamine D? versus D? receptors.
价 格:¥电议型 号:T69808产 地:中国大陆
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T69576J-104129 fumarate;化合物 J-104129 fumarateJ-104129 fumarate
J-104129 fumarate is a potent M3 muscarinic receptor antagonist.
价 格:¥电议型 号:T69576产 地:中国大陆
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T69434Methapyrilene fumarate;化合物 Methapyrilene fumarateMethapyrilene fumarate
Methapyrilene fumarate is a histamine H1 antagonist with sedative action used as a hypnotic and in allergies. It is a hepatocarcinogen in sufficiently high doses, inducing mutations through an indirect genotoxic mechanism; e.g., via an oxidative mechanism or interaction with chromosomal proteins.
价 格:¥电议型 号:T69434产 地:中国大陆
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T69306Lubabegron fumarate;化合物 Lubabegron fumarateLubabegron fumarate
Lubabegron, also known as LY591281; LY488756 fumarate, is a veterinary drug used to reduce ammonia emissions from animals and their waste. Ammonia emissions are a concern in agricultural production because of detrimental effects on the environment, human health, and animal health. Lubabegron was approved by the U.S. Food and Drug Administration in 2018 for use in feedlot cattle. Lubabegron is a beta-adrenergic receptor agonist that has the effect of increasing the breakdown of fats and increasin
价 格:¥电议型 号:T69306产 地:中国大陆
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T69156Metofenazate difumarate;化合物 Metofenazate difumarateMetofenazate difumarate
Metofenazate difumarate is a selective calmodulin inhibitor.
价 格:¥电议型 号:T69156产 地:中国大陆
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T68960F-15599 Fumarate;化合物 F-15599 FumarateF-15599 Fumarate
F-15599 Fumarate is a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity.
价 格:¥电议型 号:T68960产 地:中国大陆
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T68425Saracatinib difumarate;化合物 Saracatinib difumarateSaracatinib difumarate
Saracatinib difumarate is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities.
价 格:¥电议型 号:T68425产 地:中国大陆
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T68397Xamoterol fumarate;化合物 Xamoterol fumarateXamoterol fumarate
Xamoterol fumarate is a selective beta-1-adrenergic partial agonist. Because it is a partial agonist, it acts as an agonist when sympathetic activity is low and as an antagonist when sympathetic activity is high. It reduces myocardial ischemia and improves ventricular function in patients with mild to moderate heart failure. In patients with severe heart failure it has been shown to produce benefits in systolic and diastolic function.
价 格:¥电议型 号:T68397产 地:中国大陆
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T6541Ibutilide Fumarate;富马酸伊布利特Corvert Fumarate|||U70226E;Corvert Fumarate|||U70226E|||富马酸伊布利特
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval.
价 格:¥电议型 号:T6541产 地:中国大陆
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T6505Formoterol fumarate;福美特罗富马酸盐Formoterol Hemifumarate|||NSC 299587|||Eformoterol Hemifumarate|||CGP 25
Formoterol fumarate (Eformoterol Hemifumarate), an effective, specific and long-acting β2-adrenoceptor agonist, is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma.
价 格:¥电议型 号:T6505产 地:中国大陆
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T64175Cobimetinib hemifumarate;化合物 Cobimetinib hemifumarateCobimetinib hemifumarate
Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1.
价 格:¥电议型 号:T64175产 地:中国大陆
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T64065Siponimod hemifumarate;化合物 Siponimod hemifumarateSiponimod hemifumarate
Siponimod (BAF-312) hemifumarate is a selective and potent modulator of sphingosine-1-phosphate (S1P) receptors. Siponimod hemifumarate can be used in the study of multiple sclerosis (MS).
价 格:¥电议型 号:T64065产 地:中国大陆
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T63916MAX-40279 hemifumarate;化合物 MAX-40279 hemifumarateMAX-40279 hemifumarate
MAX-40279 hemifumarate is a potent dual inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate has shown investigational potential in acute myeloid leukaemia (AML).
价 格:¥电议型 号:T63916产 地:中国大陆
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T6364LDesfesoterodine fumarate;化合物 T6364LPNU-200577 fumarate|||UNII-607O3D83YQ;PNU-200577 fumarate|||UNII-
Desfesoterodine fumarate is a bio-active chemical. Detailed information has not been published.
价 格:¥电议型 号:T6364L产 地:中国大陆
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T63356Bopindolol fumarate;化合物 Bopindolol fumarateBopindolol fumarate
Bopindolol ((±)-Bopindolol) fumarate is an orally active β-adrenoceptor (ARs) antagonist with partial agonist activity that is non-selective for β1- and β2-ARs and has low affinity for the β3-AR subtype. Bopindolol fumarate is a precursor drug to Pindolol and can be used to study primary and renal vascular hypertension.
价 格:¥电议型 号:T63356产 地:中国大陆
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T6242Rupatadine Fumarate;富马酸卢帕他定Rinialer|||Rupafin|||Alergoliber;富马酸卢帕他定|||Rinialer|||Rupafin|||Alergolib
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.
价 格:¥电议型 号:T6242产 地:中国大陆
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T6241Quetiapine hemifumarate富马酸喹硫平Quetiapine Fumarate|||ICI-204636|||富马酸喹硫平
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
价 格:¥电议型 号:T6241产 地:中国大陆
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T60950Pirepemat fumarate;化合物 Pirepemat fumaratePirepemat fumarate
Pirepemat (IRL752) fumarate can be used in Parkinson´s disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2].
价 格:¥电议型 号:T60950产 地:中国大陆