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T82320Giloralimab;化合物 GiloralimabABBV-927;ABBV-927
Giloralimab (ABBV-927), an agonistic monoclonal antibody targeting CD40, exhibits potent activity and is being investigated for potential application in cancer research [1] [2].
价 格:¥电议型 号:T82320产 地:中国大陆
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T82271Golocdacimab;化合物 GolocdacimabMEDI6570;MEDI6570
Golocdacimab (MEDI6570) is a fully human monoclonal antibody targeting LOX-1 with potential application in type 2 diabetes research [1].
价 格:¥电议型 号:T82271产 地:中国大陆
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T82260Grisnilimab;化合物 GrisnilimabWT1;WT1
"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms´ tumor. It modulates the transcription of various genes and may be involved in post-transcriptional RNA processing [1]."
价 格:¥电议型 号:T82260产 地:中国大陆
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T82259Grisnilimab setaritox;化合物 Grisnilimab setaritoxWT1-RTA;WT1-RTA
Grisnilimab setaritox (WT1-RTA), an anti-CD7 antihuman T cell antibody linked to ricin A chain (RTA), exhibits in vitro cytotoxicity against CEM (T-lymphoblastic leukemia) cells with an ID 50 of 53 pM. The 30-kDa RTA component disrupts the function of 60S ribosomal subunits. Additionally, Grisnilimab setaritox has demonstrated efficacy in ameliorating leukemic meningitis in a rhesus monkey model [1].
价 格:¥电议型 号:T82259产 地:中国大陆
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T82083Idarucizumab;化合物 IdarucizumabBI 655075;BI 655075
Idarucizumab, a humanized monoclonal antibody fragment, serves as the first reversal agent for direct oral anticoagulants (DOACs). It specifically neutralizes the effects of oral direct thrombin inhibitors, thereby restoring hemostasis [1].
价 格:¥电议型 号:T82083产 地:中国大陆
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T82080Igovomab;化合物 IgovomabIgovomab
Igovomab is a monoclonal antibody utilized for imaging in ovarian cancer research [1].
价 格:¥电议型 号:T82080产 地:中国大陆
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T82078Iladatuzumab;化合物 IladatuzumabMCDS0593A;MCDS0593A
Iladatuzumab (MCDS0593A), a humanized IgG1 monoclonal antibody targeting CD79B, serves as a precursor for the synthesis of antibody-drug conjugates (ADCs), such as Iladatuzumab vedotin (DCDS0780A), with potential applications in B-cell non-Hodgkin lymphoma (B-NHL) research [1] [2].
价 格:¥电议型 号:T82078产 地:中国大陆
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T82045Isecarosmab;化合物 IsecarosmabM-6495;M-6495
Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a dissociation constant (K D) of 3.65 pM, exhibiting chondroprotective and anti-inflammatory properties. It has the capability to bind to albumin, which prolongs its plasma half-life [1] [2] [3].
价 格:¥电议型 号:T82045产 地:中国大陆
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T82023Ivicentamab;化合物 IvicentamabGEN-3009;GEN-3009
Ivicentamab (GEN-3009), an IgG1κ humanized monoclonal antibody targeting CD37, is utilized in cancer research [1].
价 格:¥电议型 号:T82023产 地:中国大陆
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T81968KY-1044;化合物 KY-1044SAR 445256|||Alomfilimab;SAR 445256|||Alomfilimab
KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 monoclonal antibody that targets the inducible costimulatory receptor (ICOS). This compound selectively depletes cells with high ICOS expression through antibody-dependent cellular cytotoxicity (ADCC), mediated by FcγRIIIa engagement. Meanwhile, it acts as a costimulatory molecule for cells with lower ICOS levels, such as CD8+ T Effector cells, via FcγR-dependent clustering. KY-1044 leverages varying ICOS expression levels across T-cell sub
价 格:¥电议型 号:T81968产 地:中国大陆
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T81943Lemalesomab;化合物 LemalesomabIMMU-MN3;IMMU-MN3
Lemalesomab (IMMU-MN3), a mouse IgG1 monoclonal antibody targeting NCA-90, comprises a Fab´ fragment and is utilized in the study of inflammation, infectious lesions, and infection imaging [1].
价 格:¥电议型 号:T81943产 地:中国大陆
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T81918Lodelcizumab;化合物 LodelcizumabLodelcizumab
Lodelcizumab, a monoclonal antibody, is utilized in the study of hypercholesterolemia [1].
价 格:¥电议型 号:T81918产 地:中国大陆
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T81917Lorukafusp alfa;化合物 Lorukafusp alfahu14.18-IL2|||EMD 273063|||14.18 mAb;hu14.18-IL2|||EMD 273063|||1
Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine composed of the humanized 14.18 anti-GD2 monoclonal antibody (mAb) connected to interleukin-2 (IL210). It exerts its anti-tumor effects [1] through the induction of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity. This is achieved by the targeted binding of hu14.18-IL2 to GD2-expressing tumor cells, which facilitates subsequent interaction with Fc receptors on immune effector cells, as well as the
价 格:¥电议型 号:T81917产 地:中国大陆
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T81854Marstacimab;化合物 MarstacimabPF-06741086;PF-06741086
Marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody, is utilized in hemophilia research [1] [2].
价 格:¥电议型 号:T81854产 地:中国大陆
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T81852Maslimomab;化合物 MaslimomabMaslimomab
Maslimomab, a murine monoclonal antibody, targets the T-cell receptor and functions as an immunosuppressive agent [1].
价 格:¥电议型 号:T81852产 地:中国大陆
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T81793Minretumomab;化合物 MinretumomabCC-49;CC-49
Minretumomab (CC-49), a murine monoclonal antibody targeting TAG-72 (tumor-associated glycoprotein 72), serves a role in cancer and immunity research [1] [2].
价 格:¥电议型 号:T81793产 地:中国大陆
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T81790Miptenalimab;化合物 MiptenalimabBI-754111;BI-754111
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody with a dissociation constant (K D) of 88.6 nM for h LAG-3, effectively blocking the interaction between LAG-3 and its ligand MHC-II [1].
价 格:¥电议型 号:T81790产 地:中国大陆
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T81789Miromavimab;化合物 MiromavimabM777-16-3;M777-16-3
Miromavimab (M777-16-3) is a monoclonal antibody (mAb) targeting the G-II epitope within the ectodomain of the rabies virus strain ERAGP [1].
价 格:¥电议型 号:T81789产 地:中国大陆
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T81786Mitumomab;化合物 MitumomabMitumomab
Mitumomab, an anti-idiotypic mouse IgG2b monoclonal antibody, mimics the ganglioside GD3 and is utilized in researching small-cell lung carcinoma [1].
价 格:¥电议型 号:T81786产 地:中国大陆
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T81773Modotuximab;化合物 ModotuximabSym 004|||DS 1024;Sym 004|||DS 1024
Modotuximab (Anti-Human EGFR Recombinant Antibody), an IgG1κ-type chimeric antibody, selectively binds to human EGFR protein. Incorporating elements from Futuximab, it targets two distinct, non-overlapping epitopes on EGFR, facilitating receptor cross-linking, subsequent cellular internalization, and degradation. This action confers Modotuximab´s antitumor activity in vivo [1].
价 格:¥电议型 号:T81773产 地:中国大陆