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T69937INCB059872 tosylate；化合物 INCB059872 tosylateINCB059872 tosylate
INCB059872, also known as INCB59872, is a potent, selective, and orally active lysine-specific demethylase 1 inhibitor. INCB059872 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively, through amine oxidation. LSD1 inhibition enhances H3K4 methylation and increases the expression of tumor-suppressor genes. In addition, LSD
价 格：￥电议型 号：T69937产 地：中国大陆
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T69822Ritlecitinib tosylate；化合物 Ritlecitinib tosylateRitlecitinib tosylate
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.
价 格：￥电议型 号：T69822产 地：中国大陆
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T69183APC-3316 tosylate；化合物 APC-3316 tosylateAPC-3316 tosylate
APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.
价 格：￥电议型 号：T69183产 地：中国大陆
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T6892Niraparib tosylate；尼拉帕尼对苯甲磺酸盐MK-4827 (tosylate)|||MK 4827 tosylate|||Niraparib (MK-4827) tosylate；尼拉
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
价 格：￥电议型 号：T6892产 地：中国大陆
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T68302KD3010 tosylate；化合物 KD3010 tosylateKD3010 tosylate
KD-3010 is a peroxisome proliferator-activated receptor delta agonist potentially for the treatment of diabetes and obesity. KD-3010 dramatically ameliorates liver injury induced by carbon tetrachloride (CCl(4)) injections. Deposition of extracellular matrix proteins was lower in the KD3010-treated group than in the vehicle- or GW501516-treated group. Interestingly, profibrogenic connective tissue growth factor was induced significantly by GW501516, but not by KD-3010, following CCl(4) treatmen
价 格：￥电议型 号：T68302产 地：中国大陆
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T68297Dilmapimod tosylate；化合物 Dilmapimod tosylateDilmapimod tosylate
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory distress syndrome. IL-1β was identified as a gene regulated by dilmapimod that could influence c-reactive protein levels. Dilmapimod had been in phase III clinical trials by GlaxoSmithKline for the treatment of rheumatoid arthritis, neuropathic pain, coronary artery disease (CAD) and
价 格：￥电议型 号：T68297产 地：中国大陆
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T68248F-15599 tosylate；化合物 F-15599 tosylateF-15599 tosylate
F-15599 tosylate is a selective 5-HT(1A) agonist.
价 格：￥电议型 号：T68248产 地：中国大陆
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T68082Glycopyrronium tosylate；格隆铵甲苯磺酸盐Glycopyrronium tosylate
Glycopyrronium tosylate an anticholinergic compound used in the treatment of axillary hyperhidrosis for the study of a variety of cryptobacterial tumors.
价 格：￥电议型 号：T68082产 地：中国大陆
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T6752S-Adenosyl-L-methionine disulfate tosylate；S-腺苷蛋氨酸对甲苯磺酸硫酸盐Ademetionine disulfate tosylate；S-腺苷蛋氨酸对甲苯
S-Adenosyl-L-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
价 格：￥电议型 号：T6752产 地：中国大陆
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T63965Bepotastine tosylate；化合物 Bepotastine tosylateBepotastine tosylate
Bepotastine tosylate is a selective, orally active second-generation histamine H1 receptor antagonist that exhibits an inhibitory effect on histamine-mediated upregulation of nerve growth factor (NGF) expression. conjunctivitis and urticaria/pruritus.
价 格：￥电议型 号：T63965产 地：中国大陆
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T6331Allitinib tosylate；艾力替尼AST-1306 TsOH|||AST-6|||Allitinib|||AST-1306|||AST-1306 (TsOH)；艾力替尼|||AST-130
Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.
价 格：￥电议型 号：T6331产 地：中国大陆
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T6235Lapatinib Ditosylate；二甲苯磺酸拉帕替尼Lapatinib (GW-572016) Ditosylate|||GW-572016 ditosylate|||Tykerb ditos
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
价 格：￥电议型 号：T6235产 地：中国大陆
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T4477Domatinostat tosylate；化合物4SC-202 tosylate4SC-202 tosylate|||4SC-202；4SC-202 tosylate|||4SC-202
Domatinostat tosylate (4SC-202) is a selective inhibitor of class I HDAC for HDAC1/2/3 (IC50: 1.20/1.12/0.57 μM). It also displays inhibitory activity against Lysine-specific demethylase 1 (LSD1).
价 格：￥电议型 号：T4477产 地：中国大陆
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T41316Edoxaban tosylate；化合物 Edoxaban tosylateEdoxaban tosylate
Edoxaban Tosylate (DU-176b tosylate) is an orally active, selective factor Xa inhibitor. It is an anticoagulant used to prevent stroke, is a weak inhibitor of thrombin and factor IXaβ (FIXa), and is more than 10,000-fold selective for FXa. It has antithrombotic properties and can be used in the study of thromboembolic diseases.
价 格：￥电议型 号：T41316产 地：中国大陆
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T41121Elubrixin tosylate；Elubrixin tosylateSB-656933 tosylate|||Elubrixin tosylate；SB-656933 tosylate|||El
Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b (with an IC50 of 260.7 nM) and shape change (with an IC50 of 310.5 nM). This compound holds promise for the study of inflammatory diseases, including inflammatory bowel disease and airway inflammation.
价 格：￥电议型 号：T41121产 地：中国大陆
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T4105LAFN-1252 tosylate；化合物 T4105LAPI-1252 tosylate；API-1252 tosylate
AFN-1252 tosylate is an enoyl-ACP Reductase inhibitor.
价 格：￥电议型 号：T4105L产 地：中国大陆
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T40122L-Histidine benzyl ester bistosylate；L-组氨酸苄酯对甲苯磺酸酯L-Histidine benzyl ester bistosylate
L-Histidine benzyl ester bistosylate may serve as an activator for HutP, an RNA-binding protein.
价 格：￥电议型 号：T40122产 地：中国大陆
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T37776FASN-IN-4 tosylate；化合物 FASN-IN-4 tosylateFASN-IN-4 tosylate
FASN-IN-4 tosylate is a potent fatty acid synthase (FASN) inhibitor, exhibiting an IC50 value of 10 nM. Additionally, it demonstrates inhibitory activity against SARS-CoV-2, with an EC50 of 18.6 nM [2].
价 格：￥电议型 号：T37776产 地：中国大陆
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T37469Sitamaquine tosylateSitamaquine (tosylate)Sitamaquine tosylate
Sitamaquine is an antileishmanial agent.1It is active againstL. donovani,L. infantum,L. mexicana,L. braziliensis, andL. tropica(EC50s = 9.5-19.8 μM). It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 μM.2Sitamaquine (100 μM) increases intracellular levels of reactive oxygen species (ROS) and decreases intracellular ATP levels, as well as induces phosphatidylserine externalization, chromatin f
价 格：￥电议型 号：T37469产 地：中国大陆
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T3694LTebanicline tosylate；化合物 T3694LTebanicline tosylate
Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
价 格：￥电议型 号：T3694L产 地：中国大陆
