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  • T38190Tyr-α-CGRP (rat) (trifluoroacetate salt);Tyr-α-CGRP (rat) (trifluoroacetate salt)Tyr-α-CGRP (rat) (t

    Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM.

    价 格:¥电议型 号:T38190产 地:中国大陆

  • T38153NF-κB Inhibitor (trifluoroacetate salt);NF-κB Inhibitor (trifluoroacetate salt)NF-κB Inhibitor (trif

    NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.1In this way, NF-κB inhibitor blocks gene expression that is regulated by NF-κB.2,3This peptide is commonly used to evaluate the role of NF-κB signaling in cellular responses.4,5

    价 格:¥电议型 号:T38153产 地:中国大陆

  • T38109Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt);Galanin (2-

    Galanin (2-11) amide is a synthetic peptide fragment of the neuropeptide galanin and an agonist of the galanin-2 (GAL2) receptor (EC50= 9.32 nM in a fluorescence imaging plate reader assay).1It selectively binds to the GAL2receptor (IC50= 1.76 nM for the rat receptor) over the GAL1receptor (IC50= 879 nM for the human receptor) but does also bind to the GAL3receptor (Ki= 271 nM for the rat receptor).1,2Intracerebroventricular administration of galanin (2-11) amide (1 nmol/animal) decreases immobi

    价 格:¥电议型 号:T38109产 地:中国大陆

  • T38103Defensin HNP-3 (human) (trifluoroacetate salt);Defensin HNP-3 (human) (trifluoroacetate salt)Defensi

    Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd

    价 格:¥电议型 号:T38103产 地:中国大陆

  • T37820Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt);Brain-Derived B

    Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retinal ischemia. bFGF (1-24) corresponds to amino acid residues 1-24 of the full length peptide.

    价 格:¥电议型 号:T37820产 地:中国大陆

  • T37819Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt);Brain-Deriv

    Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept

    价 格:¥电议型 号:T37819产 地:中国大陆

  • T37718Galanin (rat, mouse) (trifluoroacetate salt);Galanin (rat, mouse) (trifluoroacetate salt)GAL (rat, m

    Galanin is a neuropeptide with diverse biological activities. [1][2][3][4][5] It binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62, and 12.3 nM, respectively). [1] Galanin binds to and inhibits contraction of guinea pig gastric smooth muscle cells induced by carbachol . [2]

    价 格:¥电议型 号:T37718产 地:中国大陆

  • T37595Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt);Brain-Derived

    Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.

    价 格:¥电议型 号:T37595产 地:中国大陆

  • T37483Difelikefalin (trifluoroacetate salt);Difelikefalin (trifluoroacetate salt)Difelikefalin (trifluoroa

    Difelikefalin is a κ-opioid receptor (KOR) agonist.1It activates KOR in HEK293 cells expressing the human receptor (EC50= 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50= 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor (MOR; EC50= >1 μM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.05 m

    价 格:¥电议型 号:T37483产 地:中国大陆

  • T37478Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt);Acetyl β-Endorphin (1-26) (human) (trifluo

    Acetyl β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is also present in the human hypothalamus, where it comprises approximately 4.9% of total β-endorphin peptides. Acetyl β-endorphin (1-26) is produced through posttranslational processing of β-endorphin and is processed similarly in rat and human hypothalamus. Levels of acetyl β-endorphin (1-26) increase in the rat pars intermedia and brain stem following chronic administration of haloperidol .

    价 格:¥电议型 号:T37478产 地:中国大陆

  • T37472TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt);TAMRA-Amyloid-β (1-42) Peptide (trifluoroacet

    TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide. Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-residue protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer´s disease. Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers. TAMRA-Amyloid-β (1-42) peptide is a labeled form of Aβ42 containing carboxytetramethyl rhodamine (TAMRA), which displays excitation/emission maxima of 543/572 nm, respectivel

    价 格:¥电议型 号:T37472产 地:中国大陆

  • T37435PACAP-related Peptide (rat) (trifluoroacetate salt);PACAP-related Peptide (rat) (trifluoroacetate sa

    PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica

    价 格:¥电议型 号:T37435产 地:中国大陆

  • T37413Calcitonin (salmon) (trifluoroacetate salt);Calcitonin (salmon) (trifluoroacetate salt)Calcitonin (s

    Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. It belongs to the calcitonin family of peptides, which also includes amylin , calcitonin gene-related peptide , and adrenomedullin. The binding of salmon calcitonin to the human calcitonin receptor (CTR) is not modulated by receptor activity-modifying proteins (RAMPs), which influence affinity of human calcitonin to CTR. Salmon calcitonin binds to human CTR2 with IC50 values of 0.933, 0.224, 0.134, and

    价 格:¥电议型 号:T37413产 地:中国大陆

  • T37409DPC-AJ1951 (trifluoroacetate salt);DPC-AJ1951 (trifluoroacetate salt)DPC-AJ1951 (trifluoroacetate sa

    DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogenously express human and rat PPR, respectively (EC50s = 2.2 and 1.1 nM, respectively). DPC-AJ1915 stimulates osteoclast-mediated bone resorption in fetal rat long-bone explant cultures and increases collagen synthesis and cell proliferation in neonatal mouse parietal bone explants

    价 格:¥电议型 号:T37409产 地:中国大陆

  • T37370Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt);Amyloid-β (25-35) Peptide (human) (trifluo

    Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM.

    价 格:¥电议型 号:T37370产 地:中国大陆

  • T37367Amyloid-β (1-42) Peptide (trifluoroacetate salt);Amyloid-β (1-42) Peptide (trifluoroacetate salt)Amy

    Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer´s disease.1,2,3Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers.1Aβ42 accumulates in the brain of many transgenic mouse models of Alzheimer´s disease and, in many models, the onset of amyloid deposition positively correlates with deficits in spatial learning and memory.4

    价 格:¥电议型 号:T37367产 地:中国大陆

  • T37200Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt);Biotin-Amyloid-β (1-42) Peptide (trifluoroac

    Biotin-amyloid-β (1-42) peptide is an affinity probe that allows amyloid-β (1-42) (Aβ42) to be detected or immobilized through interaction with the biotin ligand. It has been used to identify Aβ42 interaction partners in rat hippocampal synaptosomal membranes.

    价 格:¥电议型 号:T37200产 地:中国大陆

  • T37022Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt);Enteropeptidase Fluorogenic Substrate

    Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage.1,2Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase

    价 格:¥电议型 号:T37022产 地:中国大陆

  • T36980Histone H3K27Me1 (23-34) (trifluoroacetate salt);Histone H3K27Me1 (23-34) (trifluoroacetate salt)His

    Histone H3K27Me1 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Monomethylation of histone H3 at lysine 27 is associated with actively transcribed genes and positively correlates with H3K36 trimethylation. Levels of H3K27Me1 are increased in tumor tissue isolated from patients with metastatic hormone-na ve and castration-resistant prostate cancer. Histone H3K27Me1 (23-34) has been used in epitope mapping of

    价 格:¥电议型 号:T36980产 地:中国大陆

  • T36979Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt);Histone H3 (21-44)-GK-biotin amide (trifl

    Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3.2, the histone H3.3 variant contains a serine residue at position 31 that is phosphorylated during late prometaphase and metaphase of mitosis. Histone H3 (21-44) also contains lysine residues at positions 23, 27, and 36 that are subject to methylation and acetylation, all of whi

    价 格:¥电议型 号:T36979产 地:中国大陆

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