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T16667PROTAC Sirt2 Degrader-1;化合物 T16667PROTAC Sirt2 Degrader-1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s > 100 μM)[1].
价 格:¥电议型 号:T16667产 地:中国大陆
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T16572Prasugrel (Maleic acid);马来酸普拉格雷PCR 4099 (Maleic acid);马来酸普拉格雷|||PCR 4099 (Maleic acid)
Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation. Prasugrel Maleic acid is a thienopyridine and prodrug. Prasugrel Maleic acid also inhibits platelet function.
价 格:¥电议型 号:T16572产 地:中国大陆
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T16379Oglemilast;化合物OglemilastGRC 3886;GRC 3886
Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases.
价 格:¥电议型 号:T16379产 地:中国大陆
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T16364Infigratinib phosphate;磷酸英非替尼NVP-BGJ398 phosphate|||BGJ-398 phosphate;NVP-BGJ398 phosphate|||BGJ-398
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
价 格:¥电议型 号:T16364产 地:中国大陆
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T16035Meleagrin;化合物 T16035Meleagrin
Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast malignancies. It exhibits antimicrobial and anti-proliferative activities.
价 格:¥电议型 号:T16035产 地:中国大陆
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T15645Pamicogrel;帕米格雷KBT3022;KBT3022|||帕米格雷
Pamicogrel (KBT3022) is an inhibitor of COX.
价 格:¥电议型 号:T15645产 地:中国大陆
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T15584Integrin Antagonists 27;化合物 T15584Integrin Antagonists 27
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.
价 格:¥电议型 号:T15584产 地:中国大陆
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T15570Implitapide;英普他派AEGR 427;英普他派|||AEGR 427
Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
价 格:¥电议型 号:T15570产 地:中国大陆
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T15483LEDGIN6;化合物 T15483HIV-1 integrase inhibitor 2;HIV-1 integrase inhibitor 2
HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
价 格:¥电议型 号:T15483产 地:中国大陆
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T15471Hepronicate;灭酯灵Megrin;Megrin
Hepronicate(Megrin) is a small molecule compound with hypolipidemic and vasodilatory activity.
价 格:¥电议型 号:T15471产 地:中国大陆
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T15417Griseoluteic acid;化合物 T15417Griseoluteic acid
Griseoluteic acid is a breakdown product of griseolutein A and B. Griseoluteic acid is a phenazine antibiotic and is originally isolated from S. griseoluteus.
价 格:¥电议型 号:T15417产 地:中国大陆
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T15416GR148672X化合物GR148672X4,4,4-三氟-1-(2-噻吩基)-1,2,3-丁三酮 2-[(3-甲基苯基)腙]
GR148672X is an inhibitor of triacyglycerol hydrolase (TGH) (IC50: 4 nM).
价 格:¥电议型 号:T15416产 地:中国大陆
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T15340Fosdagrocorat;化合物 T15340PF-04171327;PF-04171327
Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.
价 格:¥电议型 号:T15340产 地:中国大陆
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T15048Dagrocorat;化合物 T15048PF-00251802;PF-00251802
Dagrocorat is a novel and dissociated agonist of glucocorticoid receptor.
价 格:¥电议型 号:T15048产 地:中国大陆
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T14876Carotegrast化合物 T14876Carotegrast
Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.
价 格:¥电议型 号:T14876产 地:中国大陆
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T14875Indocyanine green吲哚菁绿Cardiogreen|||IC Green|||Foxgreen|||吲哚菁绿
Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.
价 格:¥电议型 号:T14875产 地:中国大陆
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T1478Ondansetron hydrochloride dihydrate;盐酸昂丹司琼SN 307|||NSC 665799|||GR 38032|||Ondansetron hydrochloride
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
价 格:¥电议型 号:T1478产 地:中国大陆
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T1439Lacidipine拉西地平SN-305|||拉西地平|||GX-1048|||GR-43659X
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure.
价 格:¥电议型 号:T1439产 地:中国大陆
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T1396Bemegride;贝美格Bemegrid|||3-Ethyl-3-methylglutarimide|||Agipnon;贝美格|||Bemegrid|||3-Ethyl-3-methylgluta
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.
价 格:¥电议型 号:T1396产 地:中国大陆
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T13956Uvarigrin;大花紫玉盘素Uvarigrin
Uvarigrin induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation. Uvarigrin is isolated from the roots of Uvaria calamistrata.
价 格:¥电议型 号:T13956产 地:中国大陆