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T37952Sphinganine-1-phosphate (d17:0);Sphinganine-1-phosphate (d17:0)Sphinganine-1-phosphate (d17:0);Sphin
Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. Sphinganine-1-phosphate (d17:0) levels are lower in surgical and cadaver trabecular meshwork samples isolated from patients with primary open angle glaucoma compared with control samples.
价 格:¥电议型 号:T37952产 地:中国大陆
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T37888Desacetylcephapirin sodium;脱乙酰头孢匹林钠盐Desacetylcephapirin sodium
Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin .1 Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus with MIC values of 120, 24, 34, and 0.42 μg/ml, respectively.
价 格:¥电议型 号:T37888产 地:中国大陆
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T378116-Chloro-3-indolyl-β-D-Glucuronide CHA;6-Chloro-3-indolyl-β-D-Glucuronide 环已胺盐16beta-Methyl-16alpha,
6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) is a chromogenic substrate for β-glucuronidase. 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) can be used in the histochemical analysis of β-glucuronidase activity.
价 格:¥电议型 号:T37811产 地:中国大陆
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T37775Farnesyl Pyrophosphate (ammonium salt);Farnesyl Pyrophosphate (ammonium salt)Farnesyl Pyrophosphate
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 μM), attenuating platelet aggregation. It has also been shown to regulate adipocyte function as an endogenous PPARγ agonist. Additionally, because of a flexible hydrocarbon chain that enables different conformat
价 格:¥电议型 号:T37775产 地:中国大陆
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T37691Phosphatidic Acids (egg) (ammonium salt);Phosphatidic Acids (egg) (ammonium salt)Phosphatidic Acids
Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular
价 格:¥电议型 号:T37691产 地:中国大陆
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T376362’-Deoxyguanosine 5’-monophosphate disodium;2’-脱氧鸟苷-5’-单磷酸二钠盐5′-dGMP disodium;5′-dGMP disodium
2´-Deoxyguanosine 5´-monophosphate disodium (5´-dGMP disodium) is a nucleic acid guanosine triphosphate (GTP) derivative that serves as an oxidizable target and can be used in the formation of polycomplexes with other compounds.
价 格:¥电议型 号:T37636产 地:中国大陆
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T376352’-Deoxyadenosine-5’-triphosphate trisodium;dATP钠盐dATP trisodium;dATP trisodium
2´-Deoxyadenosine-5´-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthesis or replication.
价 格:¥电议型 号:T37635产 地:中国大陆
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T37523Tenofovir diphosphate (sodium salt);Tenofovir diphosphate (sodium salt)Tenofovir diphosphate (sodium
Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA polymerase α and β, as well as mitochondrial DNA polymerase γ (Kis = 5.2, 81.7, and 59.5 μM, respectively). Tenofovir diphosphate is formed intracellularly through phosphorylation of the prodrugs tenofovir and tenofovir disoproxil by nucleotide kinases. Increased levels of tenof
价 格:¥电议型 号:T37523产 地:中国大陆
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T37521DL-Glyceraldehyde 3-phosphate;DL-甘油醛3-磷酸3-Phosphoglyceraldehyde;3-Phosphoglyceraldehyde|||DL-甘油醛3-磷酸
DL-Glyceraldehyde-3-phosphate (GADP) is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. In glycolysis, it can be derived from fructose 1,6-bisphosphate by fructose bisphosphate aldolase in a reaction that also produces dihydroxyacetone phosphate (DHAP). Triose phosphate isomerase reversibly converts DHAP to GADP. GADP is processed to 1,3-bisphosphoglycerate by glyceraldehyde phosphate dehydrogenase and NAD+.
价 格:¥电议型 号:T37521产 地:中国大陆
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T37502sn-Glycerol 3-phosphate lithium;sn-Glycerol 3-phosphate lithiumsn-Glycerol 3-phosphate lithium
sn-Glycerol 3-phosphate lithium is synthesized via the cytosolic glycerol 3-phosphate dehydrogenase pathway. This process involves the conversion of dihydroxyacetone phosphate to sn-Glycerol 3-phosphate using NADH, which is generated during glycolysis.
价 格:¥电议型 号:T37502产 地:中国大陆
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T37452Stephacidin B;Stephacidin BStephacidin B
Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc
价 格:¥电议型 号:T37452产 地:中国大陆
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T37310Diadenosine pentaphosphate pentasodium;Diadenosine pentaphosphate pentasodiumDiadenosine pentaphosph
Diadenosine pentaphosphate pentasodium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, serves as a key component of secretory vesicles in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. This compound, along with other diadenosine polyphosphates (ApnA, n=2-7), plays a crucial role in physiological processes[1][2].
价 格:¥电议型 号:T37310产 地:中国大陆
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T37309Diadenosine pentaphosphate pentaammonium;Diadenosine pentaphosphate pentaammoniumDiadenosine pentaph
Diadenosine pentaphosphate pentaammonium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, is one component of the diadenosine polyphosphates (ApnA, n=2-7) family. These compounds are found in secretory vesicles, including those in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes[1][2].
价 格:¥电议型 号:T37309产 地:中国大陆
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T372831-Palmitoyl Lysophosphatidic Acid (sodium salt);1-Palmitoyl Lysophosphatidic Acid (sodium salt)1-Pal
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, pipe
价 格:¥电议型 号:T37283产 地:中国大陆
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T372821-Palmitoyl Lysophosphatidic Acid;1-棕榈酰溶血磷脂酸1-Palmitoyl Lysophosphatidic Acid
1-Palmitoyl Lysophosphatidic Acid is an analog of LPA and improves the the action of ampicillin, piperacillin, and ceftazidime on various strains of P. aeruginosa via binding both Ca2+ and Mg2+.
价 格:¥电议型 号:T37282产 地:中国大陆
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T3718Santonin山道年驱蛔蒿|||α-santonin|||alpha-Santonin|||山道年|||Semenen
Santonin (alpha-Santonin) is a potent antiparasitic agent.
价 格:¥电议型 号:T3718产 地:中国大陆
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T37108Carboxyphosphamide;CarboxyphosphamideCarboxyphosphamide|||Carboxyphosphamide;Carboxyphosphamide|||Ca
Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1It is formed from cyclophosphamideviaoxidation of the intermediate metabolite aldophosphamide by aldehyde dehydrogenase.
价 格:¥电议型 号:T37108产 地:中国大陆
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T37060D-myo-Inositol-1,3-diphosphate (sodium salt);D-myo-Inositol-1,3-diphosphate (sodium salt)D-myo-Inosi
D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in in
价 格:¥电议型 号:T37060产 地:中国大陆
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T37059D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt);D-myo-Inositol-1,3,4,6-tetraphosphate (ammoniu
The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol
价 格:¥电议型 号:T37059产 地:中国大陆
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T37058D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt);D-myo-Inositol-1,3,4,5-tetraphosphate (sodium sa
D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell.
价 格:¥电议型 号:T37058产 地:中国大陆