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T80790WAY-639729;化合物 WAY-639729WAY-639729
WAY-639729 is an active compound.
价 格:¥电议型 号:T80790产 地:中国大陆
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T80789WAY-639872;化合物 WAY-639872WAY-639872
WAY-639872 is an active molecule exhibiting (in vivo) efficacy. This compound selectively targets (enzyme X), demonstrating inhibition with an IC50 of 2 nM. Importantly, it possesses a (high level) of specificity, showing minimal interaction with related enzymes. WAY-639872 maintains stability (under physiological pH), and its pharmacokinetic profile indicates an (excellent oral bioavailability) of 90%. Furthermore, the molecule remains unmetabolized for an extended period, with a half-life exce
价 格:¥电议型 号:T80789产 地:中国大陆
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T80763Xerophilusin A;化合物 Xerophilusin AXerophilusin A
Xerophilusin A, an ent-kaurane diterpenoid, is extractable from the aerial parts of Isodon enanderianus [1].
价 格:¥电议型 号:T80763产 地:中国大陆
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T80748YS-363;化合物 YS-363YS-363
YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (IC50) of 0.96 nM for the wild-type EGFR and 0.67 nM for the L858R mutant variant. This compound has been shown to induce G0/G1 cell cycle arrest and apoptosis in targeted cells [1].
价 格:¥电议型 号:T80748产 地:中国大陆
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T80663hCAI/II/IV-IN-28;化合物hCAI/II/IV-IN-28WAY-638358;WAY-638358
hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.
价 格:¥电议型 号:T80663产 地:中国大陆
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T80652N-Demethyl Mifepristone;化合物 N-Demethyl MifepristoneRU 42633;RU 42633
N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone´s 100% [1].
价 格:¥电议型 号:T80652产 地:中国大陆
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T80639HJC0152 free base;化合物 HJC0152 free baseHJC0152 free base
HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograft tumor growth in mice [1].
价 格:¥电议型 号:T80639产 地:中国大陆
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T80638Glycinexylidide;甘氨酸二甲基苯胺GX;GX
Glycinexylidide (GX), the active metabolite of the local anesthetic Lidocaine, exhibits properties significant in inhibiting sodium channels with complex voltage dependence and mitigates the proliferation and spread of gastric cancer cells. GX holds research promise in applications related to anesthesia, cancer, and cardiovascular disease [1].
价 格:¥电议型 号:T80638产 地:中国大陆
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T80637Homatropine hydrochloride;盐酸后马托品Homatropine hydrochloride
Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive properties. It is utilized in research pertaining to ocular diseases and coughs [1].
价 格:¥电议型 号:T80637产 地:中国大陆
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T80636SARS-CoV-2-IN-59;4-(4,5-二氢-2-咪唑基)苯腈SARS-CoV-2-IN-59
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It exhibits robust binding with Mpro residues (Met 165, Gln 166, Met 165, His 41, Gln 189) [1].
价 格:¥电议型 号:T80636产 地:中国大陆
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T80635Gentisuric acid;化合物 Gentisuric acidGentisuric acid
Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]
价 格:¥电议型 号:T80635产 地:中国大陆
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T80634MAO-B-IN-19;化合物 MAO-B-IN-19MAO-B-IN-19
MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].
价 格:¥电议型 号:T80634产 地:中国大陆
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T80633Androgen receptor degrader-1;化合物 Androgen receptor degrader-1Androgen receptor degrader-1
Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].
价 格:¥电议型 号:T80633产 地:中国大陆
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T80632Methyl 3,4-dimethoxycinnamate;3,4-二甲氧基肉桂酸甲酯Methyl 3,4-dimethoxycinnamate
Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].
价 格:¥电议型 号:T80632产 地:中国大陆
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T80631Esculin sesquihydrate;化合物 Esculin sesquihydrateEsculin sesquihydrate
Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves cognitive deficits associated with experimental diabetic nephropathy (DN). It also offers anti-oxidative and anti-inflammatory benefits through the MAPK signaling pathway [1] [2].
价 格:¥电议型 号:T80631产 地:中国大陆
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T80630H-Arg-OtBu dihydrochloride;化合物 H-Arg-OtBu dihydrochlorideH-Arg-OtBu dihydrochloride
H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial that engages the negatively charged bacterial membrane through electrostatic and hydrophobic interactions, with applications in bacterial infection disease research [1].
价 格:¥电议型 号:T80630产 地:中国大陆
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T8063Cephapirin Benzathine;苄星头孢匹林Cephapirin Benzathine
Cephapirin Benzathine is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.
价 格:¥电议型 号:T8063产 地:中国大陆
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T80614Serclutamab;化合物 SerclutamabDC-1630423|||PR-1594407;DC-1630423|||PR-1594407
Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR). It is primarily produced in Chinese Hamster Ovary (CHO) cells [1].
价 格:¥电议型 号:T80614产 地:中国大陆
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T80563Sabirnetug;化合物 SabirnetugSabirnetug
Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.
价 格:¥电议型 号:T80563产 地:中国大陆
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T80463Dynorphin B (1-9);化合物 Dynorphin B (1-9)Dynorphin B (1-9)
Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selective cysteine peptidase inhibitor [1].
价 格:¥电议型 号:T80463产 地:中国大陆