T21818Pregnenolone CarbonitrileCYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 1

Pregnenolone Carbonitrile is an activator of rodent-PXR and induces the expression of CYP3A.

价 格：￥电议型 号：T21818产 地：中国大陆

T101083-Bromocytisine

3-Bromocytisine is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).

价 格：￥电议型 号：T10108产 地：中国大陆

T6740Bafilomycin A1Autophagy,Proton Pump,Bafilomycin A 1,Bafilomycin A1,Bafilomycin A-1,Antibiotic,BafA1,

Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways. Bafilomycin A1 is a vacuolar H+-ATPase inhibitor (IC50: 0.44 nM). It is also found to inhibit autophagy while induces apoptosis.Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice.

价 格：￥电议型 号：T6740产 地：中国大陆

T8933JNJ-63576253 free baseJNJ 63576253 free base,resistant,TRC 253,JNJ63576253,TRC-253,CRPC,JNJ63576253

JNJ-63576253 is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC).

价 格：￥电议型 号：T8933产 地：中国大陆

T7914Acenaphthylenearomatic,hydrocarbon,polycyclic,Acenaphthylene,Inhibitor,inhibit

Acenaphthylene is environmental polycyclic aromatic hydrocarbon (PAH)pollutants

价 格：￥电议型 号：T7914产 地：中国大陆

T9352hydrocotarnineE3 ligating enzyme,IL-18,NLRP3,E1/E2/E3 Enzyme,hydrocotarnine,inflammasome activation,

hydrocotarnine?is an inhibitor of Cbl.

价 格：￥电议型 号：T9352产 地：中国大陆

Fr14145Compound Fr14145Compound Fr14145

价 格：￥电议型 号：Fr14145产 地：中国大陆

T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,

AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.

价 格：￥电议型 号：T8684产 地：中国大陆

T72722,3,5-TRIFLUORO-4-(TRIFLUOROMETHYL)PYRIDINE2,3,5TRIFLUORO4(TRIFLUOROMETHYL)PYRIDINE,2,3,5 TRIFLUORO

价 格：￥电议型 号：T7272产 地：中国大陆

T7631LEledoisin Related Peptide 2TFAEledoisin Related Peptide 2TFA

Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.

价 格：￥电议型 号：T7631L产 地：中国大陆

T17006TC-I 2014TCI 2014,TC I 2014

TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectively).

价 格：￥电议型 号：T17006产 地：中国大陆

TP1104LMelanin Concentrating Hormone, salmon acetateMelanin Concentrating Hormone, salmon acetate

Melanin Concentrating Hormone, salmon acetate is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.

价 格：￥电议型 号：TP1104L产 地：中国大陆

T12589PI3Kα/mTOR-IN-1PI3Kα/mTORIN1,PI3Kα/mTOR IN 1,PI-3Kα/mTOR-IN-1

PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR. PI3Kα/mTOR-IN-1 shows an IC50 of 7 nM for PI3Kα in a cell assay, and Kis of 12.5 nM and 10.6 nM for mTOR and PI3Kα in a cell free assay , respectively.

价 格：￥电议型 号：T12589产 地：中国大陆

TN4618N-trans-SinapoyltyramineN trans Sinapoyltyramine,NtransSinapoyltyramine

N-trans-Sinapoyltyramine exhibited strong and selective cytotoxicity on the HeLa human cancer cell line with IC50 values of 9.77 ± 1.25 Μm.

价 格：￥电议型 号：TN4618产 地：中国大陆

T7831NitecaponeGSH,Nitecapone,glutathione,OR-462,Inhibitor,ROS,Parkinson,COMT,OR 462,inhibit,OR462,allody

Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)

价 格：￥电议型 号：T7831产 地：中国大陆

TMA2613Cyclo(Pro-Leu)

Cyclo(Pro-Leu) is a marine-derived natural product with brine shrimp lethality.

价 格：￥电议型 号：TMA2613产 地：中国大陆

T6972RS-1RAD51,RS1,RS-1,inhibit,Inhibitor,RS 1,CRISPR/Cas9

RS-1 is a RAD51 activator. RS-1 also increases CRISPR/Cas9-mediated knock-in efficiencies.

价 格：￥电议型 号：T6972产 地：中国大陆

T6702TerbinafineFungal,bacteria,Candida,Inhibitor,squalene epoxidase,Terbinafine,Bacterial,Antibiotic,TDT

Terbinafine is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.

价 格：￥电议型 号：T6702产 地：中国大陆

T61112SLF1081851

SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.

价 格：￥电议型 号：T61112产 地：中国大陆

T17005FPR Agonist 43FPR Agonist 43

FPR Agonist 43 is a dual agonist of formyl peptide receptor 1 and formyl peptide receptor 2 (FPR2)/ALX.

价 格：￥电议型 号：T17005产 地：中国大陆