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T62089FWM-1；化合物 FWM-1FWM-1
FWM-1 is a potent inhibitor of SARS-COV-2 NSP13 resolvase (free energy of binding: -328.6 kcal/mol).FWM-1 shows effective disruption of the binding of ATP to SARS-COV2 resolvase.
价 格：￥电议型 号：T62089产 地：中国大陆
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T62088TRPC5-IN-2；化合物 TRPC5-IN-2TRPC5-IN-2
TRPC5-IN-2 is a potent inhibitor of TRPC5.
价 格：￥电议型 号：T62088产 地：中国大陆
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T62087Tuberculosis inhibitor 4；化合物 Tuberculosis inhibitor 4Tuberculosis inhibitor 4
Tuberculosis inhibitor 4 (compound 16) is a spirothiazolidinone based on mandelic acid that exhibits potent antimycobacterial action. The inhibitor inhibited 98% of Mycobacterium tuberculosis strain H37Rv at concentrations below 6 μg mL.
价 格：￥电议型 号：T62087产 地：中国大陆
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T62086Tuberculosis inhibitor 5；化合物 Tuberculosis inhibitor 5Tuberculosis inhibitor 5
Tuberculosis inhibitor 5 (Compound 11i) is a potent anti-tuberculosis agent with no apparent cytotoxicity. tuberculosis inhibitor 5 is an antimycobacterial biphenyl analogue.
价 格：￥电议型 号：T62086产 地：中国大陆
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T62085Enpp-1-IN-5；化合物 Enpp-1-IN-5Enpp-1-IN-5
Enpp-1-IN-5 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). enpp 1 shows broad specificity and is able to cleave a wide range of substrates (including phosphodiester bonds of nucleotides and nucleotides, and pyrophosphate bonds of nucleotides and nucleotides). Enpp-1-IN-5 has potential for cancer and infectious disease research.
价 格：￥电议型 号：T62085产 地：中国大陆
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T62084ATR-IN-8；化合物 ATR-IN-8ATR-IN-8
ATR-IN-8 is a potent inhibitor of ATR. ATR-IN-8 has shown potential research value in cancer diseases.
价 格：￥电议型 号：T62084产 地：中国大陆
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T62083Camonsertib；化合物CamonsertibATR inhibitor 4|||RP-3500；ATR inhibitor 4|||RP-3500
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR (IC50: 120 nM) and is a more active inhibitor of ATM, DNA-PK and PI3Kα kinases. PK and PI3Kα kinases.
价 格：￥电议型 号：T62083产 地：中国大陆
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T62082FPPQ；化合物 FPPQFPPQ
FPPQ is a dual antagonist of the 5-HT3 and 5-HT6 receptors with Ki values of 0.9 nM and 3 nM, respectively, and exhibits antipsychotic and pro-cognitive activity.
价 格：￥电议型 号：T62082产 地：中国大陆
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T62081Mt KARI-IN-5；化合物 Mt KARI-IN-5Mt KARI-IN-5
Mt KARI-IN-5 (compound 6c) was a potent inhibitor of Mycobacterium tuberculosis ketohydrin reductase I (MtbKARI) (Ki: 4.72 μM). Mt KARI-IN-5 exhibited inhibition of MtbH37Rv activity with a MIC value of 1.56 μM, low cytotoxicity and an IC50 value for HEK The IC50 value for HEK was greater than 64 μg/mL.
价 格：￥电议型 号：T62081产 地：中国大陆
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T62080GSK3494245；化合物 GSK3494245GSK3494245
GSK3494245 (DDD01305143) is a potent, selective, orally active inhibitor of chymotrypsin-like activity that binds to the proteasome of WTL.donovani at an IC50 of 0.16 μM, sandwiched between the β4 and β5 subunits. GSK3494245 exhibits good biosafety properties. GSK3494245 is a suitable inhibitor of the chymotrypsin-like activity of the human proteasome (IC50: 26S=13 μM; enriched THP-1 extract IC50=40 μM).
价 格：￥电议型 号：T62080产 地：中国大陆
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T6208AS-252424；化合物AS-252424AS-252424
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
价 格：￥电议型 号：T6208产 地：中国大陆
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T62079MEK4 inhibitor-2；化合物 MEK4 inhibitor-2MEK4 inhibitor-2
MEK4 Inhibitor-2, a novel MEK4 inhibitor, demonstrates efficacy against pancreatic adenocarcinoma, exhibiting an IC50 value of 83 nM.
价 格：￥电议型 号：T62079产 地：中国大陆
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T62078Akt/NF-κB/JNK-IN-1；化合物 Akt/NF-κB/JNK-IN-1Akt/NF-κB/JNK-IN-1
Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide production (IC50: 3.15 μM) and shows anti-inflammatory effects.
价 格：￥电议型 号：T62078产 地：中国大陆
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T62077VT103；化合物VT103VT-103|||VT 103；VT-103|||VT 103
VT103 is an orally active and selective inhibitor of TEAD1 protein palmitoylation and is an analog of VT101. VT103 has potential antitumor activity by inhibiting YAP/TAZ-TEAD-promoted gene transcriptionment, blocking TEAD auto-palmitoylation, and blocking the interaction between YAP/TAZ and TEAD.VT103 can be used in the study of HER2-positive breast cancer, prostate cancer, and triple-negative breast cancer.
价 格：￥电议型 号：T62077产 地：中国大陆
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T62076LPM4870108；化合物 LPM4870108LPM4870108
LPM4870108 is a potent, orally active pan-Trk (WT/MT) inhibitor that acts on TrkC (IC50: 0.2 nM), TrkA (IC50: 2.4 nM), TrkAG595R (IC50: 3.5 nM) and TrkAG667C (IC50: 2.3 nM), and is more selective for Trk than ALK (IC50: 2.3 nM). LPM4870108 showed anti-tumour effects.
价 格：￥电议型 号：T62076产 地：中国大陆
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T62075HSV-1/HSV-2-IN-1；化合物 HSV-1/HSV-2-IN-1HSV-1/HSV-2-IN-1
HSV-1/HSV-2-IN-1 is an HSV-1 and HSV-2 inhibitor that acts against HSV-1 (KOS) (EC50: 7.6 μM), HSV-2 (G) (EC50: 7.6 μM), HSV-1 TK-KOS ACVr (EC50: 4 μM) and cowpox virus (EC50: 12 μM).
价 格：￥电议型 号：T62075产 地：中国大陆
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T62074MYF-03-176；化合物 MYF-03-176MYF-03-176
MYF-03-176 is an orally active anticancer agent. MYF-03-176 exhibits strong antitumour effects in the MPM mouse xenograft tumour model following oral administration.
价 格：￥电议型 号：T62074产 地：中国大陆
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T62073PI3Kα-IN-6；化合物 PI3Kα-IN-6PI3Kα-IN-6
PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells. PI3Kα-IN-6 increases ROS production, decreases mitochondrial membrane potential and induces apoptosis.
价 格：￥电议型 号：T62073产 地：中国大陆
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T62072HDAC-IN-47；化合物 HDAC-IN-47HDAC-IN-47
HDAC-IN-47 is an orally active histone deacetylase (HDAC) inhibitor with IC50 values of 19.75 nM, 57.8 nM, 40.27 nM, 5.63 nM and 302.73 nM for HDAC1, HDAC2, HDAC3, HDAC6 and HDAC8, respectively. HDAC-IN-47 can block the cell cycle in G2/M phase, inhibit autophagy, induce apoptosis using the Bax/Bcl-2 and caspase-3 pathways, and has anti-cancer activity in vivo.
价 格：￥电议型 号：T62072产 地：中国大陆
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T62071VEGFR-2-IN-16；化合物 VEGFR-2-IN-16VEGFR-2-IN-16
VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects.
价 格：￥电议型 号：T62071产 地：中国大陆
