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T9609GRK5-IN-2metabolic,bicyclic,insulin,kinase,inhibit,Inhibitor,disease,pyridine-based,GRK5 IN 2,GRK-5-
GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.
价 格:¥电议型 号:T9609产 地:中国大陆
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T7622GabazineInhibitor,Gamma-aminobutyric acid Receptor,Gabazine,γ-Aminobutyric acid Receptor,inhibit,SR
Gabazine is an antagonist of GABAA receptors (Ki : 74-150 nM)
价 格:¥电议型 号:T7622产 地:中国大陆
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TP2212La-MSH, amide Acetate(581-05-5 free base)a MSH, amide Acetate(581 05 5 free base),aMSH, amide Acetate
a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC)
价 格:¥电议型 号:TP2212L产 地:中国大陆
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T67742EX-A5386
EX-A5386 is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.
价 格:¥电议型 号:T67742产 地:中国大陆
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T37082HS271HS271,HS-271
HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM). HS271 shows excellent enzymatic and cellular activities, as well as excellent pharmacokinetic properties.
价 格:¥电议型 号:T37082产 地:中国大陆
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TQ0271Falnidamol
Falnidamol is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50>10 μM). Falnidamol is a pyrimido-pyrimidine compound and has anti-cancer activity.
价 格:¥电议型 号:TQ0271产 地:中国大陆
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TP1086Men 10376 TFA(135306-85-3,free)Men 10376 TFA(135306853,free),Men 10376 TFA(135306 85 3,free)
Men 10376 TFA is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats.
价 格:¥电议型 号:TP1086产 地:中国大陆
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T11178LELN318463 racemate
ELN318463 racemate is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
价 格:¥电议型 号:T11178L产 地:中国大陆
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TCS0102PulegoneEndogenous Metabolite,Transient receptor potential channels,TRP Channel,Pulegone,Inhibitor,i
1. Pulegone has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect that appears to independ on the opening of L-type calcium channels. 3. Pulegone has negative reinforcing properties and seems to possess anxiolytic-like actions unrelated to the benzodiazepine site of the γ-aminobutyric acid type A (GABAA) receptor.
价 格:¥电议型 号:TCS0102产 地:中国大陆
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TN6732Oenothein Bantitumor,HCV,Hepatitis C virus,ellagitannin,antifungal,antioxidant,Bacterial,inhibit,Oen
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
价 格:¥电议型 号:TN6732产 地:中国大陆
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T6944Thiophanate-MethylThiophanate-Methyl,inhibit,Inhibitor,Thiophanate Methyl,ThiophanateMethyl,Fungal
Thiophanate-Methyl (TM), a methyl benzimidazole carbamate (MBC) fungicide,
价 格:¥电议型 号:T6944产 地:中国大陆
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T79823,6-Dihydroxyflavoneinhibit,Inhibitor,caspase cascade,cell viability,oxidative stress,3,6-DHF,Apopto
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.
价 格:¥电议型 号:T7982产 地:中国大陆
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T63812MrgprX2 antagonist-8
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.
价 格:¥电议型 号:T63812产 地:中国大陆
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TL0002Liquiritin apiosideInhibitor,Liquiritin apioside,inhibit
Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia.
价 格:¥电议型 号:TL0002产 地:中国大陆
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T8485THIQmutant,MC Receptor,inhibit,THIQ,melanocortin,affinity,activity,erectile,selective,eliciting,Mela
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
价 格:¥电议型 号:T8485产 地:中国大陆
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T8556Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)Z Gly Gly Arg AMC TFA (66216 78 2 free base),ZGlyGlyArgA
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
价 格:¥电议型 号:T8556产 地:中国大陆
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TP1045LOrexin B, rat, mouse AcetateOrexin B, rat, mouse Acetate
Orexin B, rat, mouse Acetate is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
价 格:¥电议型 号:TP1045L产 地:中国大陆
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TN1544D-MentholD-Menthol,Microcystis aeruginosa,Inhibitor,Anaesthetic,D Menthol,inhibit,DMenthol
D-Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α±7-nACh receptors in a noncompetitive manner.
价 格:¥电议型 号:TN1544产 地:中国大陆
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T8012Scyllo-InositolScyllo Inositol,Inhibitor,Abeta,ScylloInositol,Scyllo-Inositol,Amyloid-β,β-amyloid pe
Scyllo-Inositol is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for Alzheimer´s disease.
价 格:¥电议型 号:T8012产 地:中国大陆
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T60202MMRi62
MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutat
价 格:¥电议型 号:T60202产 地:中国大陆