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T77761BMS-502;化合物 BMS-502BMS-502
BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune responses in a dose-dependent manner and can be used to study immune-related diseases.
价 格:¥电议型 号:T77761产 地:中国大陆
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T77508A2B receptor antagonist 2 hydrochloride;化合物T77508A2B receptor antagonist 2 hydrochloride
A2B receptor antagonist 2 hydrochloride is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
价 格:¥电议型 号:T77508产 地:中国大陆
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T77087Mipeginterferon alfa-2b;化合物 Mipeginterferon alfa-2bMipeginterferon alfa-2b
Mipeginterferon alfa-2b, an analog of interferon alpha-2b (IFNA2B), features an average substitution of 5 among its 11 amino groups (one N-terminal and 10 lysine N6), and exhibits a relative molecular mass of 40 kDa [1].
价 格:¥电议型 号:T77087产 地:中国大陆
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T76943Cepeginterferon alfa-2b;化合物 Cepeginterferon alfa-2bCepeginterferon alfa-2b
Cepeginterferon alfa-2b, a pegylated interferon, features a polyethylene glycol (PEG) base with a molecular weight of 20 kDa. This compound is utilized in the research of numerous diseases, including hepatitis C virus (HCV), polycythemia vera (PV), and essential thrombocythemia (ET) [1] [2].
价 格:¥电议型 号:T76943产 地:中国大陆
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T76853Ropeginterferon alfa-2b;化合物 Ropeginterferon alfa-2bRopeginterferon alfa-2b
Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft), a monopegylated interferon-alpha (IFN-α), is utilized in the study of myeloproliferative neoplasms [1].
价 格:¥电议型 号:T76853产 地:中国大陆
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T76069Tat-NR2Baa TFA;化合物 Tat-NR2Baa TFATat-NR2Baa TFA
Tat-NR2BAA TFA serves as the inactive control peptide for Tat-NR2B9c, featuring a comparable sequence with a crucial distinction: a double-point mutation in its COOH-terminal tSXV motif. This alteration renders Tat-NR2BAA TFA unable to bind to PSD-95, in contrast to Tat-NR2B9c. The latter is a membrane-permeant peptide that impedes PSD-95/NMDAR interaction, specifically detaching NR2B- and/or NR2A-type NMDARs from PSD-95 [1].
价 格:¥电议型 号:T76069产 地:中国大陆
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T758092B-(SP) (TFA);化合物 2B-(SP) (TFA)2B-(SP) (TFA)
2B-(SP) TFA, an eIF2B-based substrate, is efficiently phosphorylated by both α and β isoforms of Glycogen Synthase Kinase-3 (GSK-3) [1].
价 格:¥电议型 号:T75809产 地:中国大陆
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T75513BChE-IN-12;化合物 BChE-IN-12BChE-IN-12
BChE-IN-12, also known as compound 12, is a potent non-competitive inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 2.3 μM. Derived from Bletilla striata, it is utilised in research related to Alzheimer´s disease (AD) [1].
价 格:¥电议型 号:T75513产 地:中国大陆
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T75284Biotin-Vitamin B12;化合物 Biotin-Vitamin B12Biotin-Vitamin B12
Biotin-Vitamin B12, a biotinylated form of Vitamin B12, is essential for normal brain and nervous system functions as well as blood formation [1].
价 格:¥电议型 号:T75284产 地:中国大陆
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T74854GluN2B-NMDAR antagonist-1;化合物 GluN2B-NMDAR antagonist-1GluN2B-NMDAR antagonist-1
GluN2B-NMDAR Antagonist-1, an orally active compound, functions as a GluN2B-NMDAR antagonist with neuroprotective properties. It is applicable in the research of ischemic injury [1].
价 格:¥电议型 号:T74854产 地:中国大陆
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T74823Bromodomain IN-2;化合物 Bromodomain IN-2Bromodomain IN-2
BD-IN-1, a pan bromodomain (BD) inhibitor, exhibits K_D values of 250 nM for BRD4(1), 420 nM for CBP, 130 nM for BRPF1B, 430 nM for BRD7, 67 nM for BRD9, 240 nM for BRDT(1), and 970 nM for CECR2, respectively. This compound demonstrates antiproliferative activity [1].
价 格:¥电议型 号:T74823产 地:中国大陆
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T73696Peginterferon alfa-2b;化合物 Peginterferon alfa-2bPeginterferon alfa-2b
Peginterferon alfa-2b (Sch 54031), a recombinant alfa-2b interferon covalently bonded to polyethylene glycol (PEG), acts as an immunomodulator. This compound is effective in reducing viral DNA in HIV and has potential applications in melanoma research [1] [2].
价 格:¥电议型 号:T73696产 地:中国大陆
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T73552BPDA2;化合物 BPDA2BPDA2
BPDA2 is a selective and potent SHP2 inhibitor with IC50 values of 92.0 nM, 33.39 μM, and 40.71 μM for SHP2, SHP1, and SHP1B, respectively.DBDA2 possesses anticancer and antitumor activity and inhibits anchorage-independent growth of breast cancer cells and cancer stem cell properties in a concentration-dependent manner.BPDA2 can be used to study of breast cancer.
价 格:¥电议型 号:T73552产 地:中国大陆
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T73391BLM-IN-2;化合物 BLM-IN-2BLM-IN-2
BLM-IN-2, a Bloom´s Syndrome Protein (BLM) inhibitor, exhibits an IC50 of 0.8 μM and shows efficacy in suppressing proliferation, invasion, cell cycle arrest, and apoptosis in colorectal cancer (CRC) cells, making it a potential candidate for CRC research.
价 格:¥电议型 号:T73391产 地:中国大陆
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T73275BTK-IN-22;化合物 BTK-IN-22BTK-IN-22
BTK-IN-22, a BTK inhibitor (IC 50: 0.9 nM), also exhibits inhibition against BLX and BMX with IC 50 values of 1.4 and 1.2 nM, respectively. Demonstrating enhanced kinase selectivity, BTK-IN-22 outperforms Ibrutinib in this regard [1].
价 格:¥电议型 号:T73275产 地:中国大陆
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T73182BSJ-04-122;化合物BSJ-04-122BSJ-04-122
BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively.BSJ-04-122 can be used for cancer research.
价 格:¥电议型 号:T73182产 地:中国大陆
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T72887NS2B/NS3-IN-7;化合物 NS2B/NS3-IN-7NS2B/NS3-IN-7
NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells.
价 格:¥电议型 号:T72887产 地:中国大陆
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T71958BZX2;化合物 BZX2BZX2
BZX2 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.
价 格:¥电议型 号:T71958产 地:中国大陆
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T71694BRD73842;化合物 BRD73842BRD73842
BRD73842 is an inhibitor of Plasmodium PI4K.
价 格:¥电议型 号:T71694产 地:中国大陆
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T71640BMS-741672;化合物 BMS-741672BMS-741672
BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.
价 格:¥电议型 号:T71640产 地:中国大陆