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TP1543LG280-9 acetate(156761-76-1 free base)G280 9 acetate(156761 76 1 free base),G-280-9 acetate(156761-76
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.
价 格:¥电议型 号:TP1543L产 地:中国大陆
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T14303Alrizomadlin
Alrizomadlin is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.
价 格:¥电议型 号:T14303产 地:中国大陆
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T64373CDK1-IN-2
CDK1-IN-2 is a CDK1 inhibitor with IC50 of 5.8 μM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases.
价 格:¥电议型 号:T64373产 地:中国大陆
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T7424NDI-091143NDI 091143,ACLY,inhibit,ATP Citrate Lyase,NDI-091143,NDI091143,Inhibitor
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
价 格:¥电议型 号:T7424产 地:中国大陆
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T9243PFI-90antitumor,Inhibitor,PFI 90,differentiation,PAX3-FOXO1,demethylase,PFI-90,apoptosis,histone,His
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action.PFI-90 has the potential for the antitumor activity. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased.
价 格:¥电议型 号:T9243产 地:中国大陆
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T7393ONO-7300243ONO7300243,inhibit,Inhibitor,ONO 7300243,ONO-7300243,LPL Receptor,Lysophospholipid Recept
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).
价 格:¥电议型 号:T7393产 地:中国大陆
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T64376WAY-652509WAY652509
WAY-652509 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.
价 格:¥电议型 号:T64376产 地:中国大陆
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T7134MavacamtenMyosin,Inhibitor,inhibit,SAR 439152,SAR-439152,Mavacamten,MYK 461,MYK461
MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
价 格:¥电议型 号:T7134产 地:中国大陆
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T9433Nickel(II) oxideNickel(II) oxide
Nickel(II) oxide is the chemical compound with the formula NiO. It is the principal oxide of nickel.
价 格:¥电议型 号:T9433产 地:中国大陆
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TN13438-GeranyloxypsoralenCYPs,Cytochrome P450,8Geranyloxypsoralen,inhibit,8-Geranyloxypsoralen,Inhibitor,
8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.
价 格:¥电议型 号:TN1343产 地:中国大陆
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T6430CalcifediolVitamin D receptor,Calcifediol,VD/VDR,Vitamin D,Inhibitor,inhibit,Endogenous Metabolite
Calcifediol(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
价 格:¥电议型 号:T6430产 地:中国大陆
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T74373-(3-Hydroxyphenyl)propionic Acidaortic,Inhibitor,rings,Endogenous Metabolite,3(3Hydroxyphenyl)propi
3-(3-Hydroxyphenyl)propionic Acid is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.
价 格:¥电议型 号:T7437产 地:中国大陆
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T7436CilofexorGS9674,Inhibitor,inhibit,NR1H4,FXR,Cilofexor,PSC,GS 9674,oral,NASH,GS-9674,antifibrotic,non
Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.
价 格:¥电议型 号:T7436产 地:中国大陆
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T64344N-Methyl-DL-aspartic acidNMethylDLasparticacid
N-Methyl-DL-aspartic acid is a glutamate analogue and a NMDA receptor agonist and can be used for neurological diseases research.
价 格:¥电议型 号:T64344产 地:中国大陆
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T6434CCG-50014Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,in
CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
价 格:¥电议型 号:T6434产 地:中国大陆
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T9843WAY-297342WAY 297342,WAY297342
FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia [1].
价 格:¥电议型 号:T9843产 地:中国大陆
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T64332Glimepiride sulfonamide
Glimepiride sulfonamide is an antiinflammatory agent.
价 格:¥电议型 号:T64332产 地:中国大陆
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T643631-Pentalenol, 5-hexyl-1,2,3,3a,6,6a-hexahydro-4-phenyl-3a-(1-phenylethenyl)-, (1R,3aS,6aS)-rel-1Pent
1-Pentalenol, 5-hexyl-1,2,3,3a,6,6a-hexahydro-4-phenyl-3a-(1-phenylethenyl)-, (1R,3aS,6aS)-rel- is a potent liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1) agonist with pEC 50 s of 6.4 and 7.2, respectively.
价 格:¥电议型 号:T64363产 地:中国大陆
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T22812GRI977143GRI977143,GRI-977143
GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragmentation.
价 格:¥电议型 号:T22812产 地:中国大陆
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T64342DC-TEADin02DCTEADin02
DC-TEADin02 is an inhibitor of TEAD auto palmitoylation (IC50 = 197 nM). DC-TEADin02 can be in studies about development, regeneration, and tissue homeostasis.
价 格:¥电议型 号:T64342产 地:中国大陆