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T7460α-Cyano-4-hydroxycinnamic acidmatrix-assisted,MALDI-TOF,matrix,Inhibitor,lactate,applications,MCTs,p
α-Cyano-4-hydroxycinnamic acid (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate transport in rat heart mitochondria (IC50 : 1.5 μM).
价 格:¥电议型 号:T7460产 地:中国大陆
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T67846AKR1C3-IN-9
AKR1C3-IN-9 is a selective Aldo-keto Reductase 1C3 (AKR1C3) inhibitor (IC50= 8.92 nM). AKR1C3-IN-9 can significantly reverse the Doxorubicin (DOX) resistance in a resistant breast cancer cell line.
价 格:¥电议型 号:T67846产 地:中国大陆
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TQ0232UNC0646H3K9me2,KMT1D,chromatin,EHMT1,Histone Methyltransferase,UNC-0646,SAR,inhibit,G9a,GLP,PKMT,UNC
UNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646 potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
价 格:¥电议型 号:TQ0232产 地:中国大陆
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T8399Crizotinib hydrochlorideCD246,PF-02341066,ROS Kinase,Autophagy,ALK tyrosine kinase receptor,Anaplast
Crizotinib hydrochloride is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)
价 格:¥电议型 号:T8399产 地:中国大陆
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T34698Spongosine
Spongosine is a pivotal intercellular signal transmitter, which has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Spongosine is a natural product isolated from Marine organisms, and first isolated from the marine sponge Cryptotethia crypta in 1950
价 格:¥电议型 号:T34698产 地:中国大陆
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TN4662NonanalB. cereus,inhibit,Inhibitor,antidiarrhoeal,fatty aldehyde,Nonanal
Nonanal is a growth factor for wood-rotting fungi. Nonanal is a potential attractant for the pine shoot beetle.
价 格:¥电议型 号:TN4662产 地:中国大陆
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TN4660NiranthinNiranthin,inhibit,anti-leishmanial agent,leishmaniasis,Topoisomerase,Parasite,drug-resistan
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
价 格:¥电议型 号:TN4660产 地:中国大陆
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T94622-Amino-6-cyclopropylamino-9H-purine2 Amino 6 cyclopropylamino 9H purine,2Amino6cyclopropylamino9Hpu
2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine
价 格:¥电议型 号:T9462产 地:中国大陆
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T6182TirofibanL-700462,VEGF,Tirofiban,L 700462,AMI,Inhibitor,Integrin,inhibit,MK-383,ACSs,antithrombotic,
Tirofiban (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
价 格:¥电议型 号:T6182产 地:中国大陆
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T7214TEPP-46TEPP46,TEPP 46,Pyruvate Kinase,ML 265,ML-265,Inhibitor,TEPP-46,inhibit
ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. .
价 格:¥电议型 号:T7214产 地:中国大陆
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T8357SB-200646electrophysiological,5-HT Receptor,SNC,Serotonin Receptor,Inhibitor,antipsychotic,inhibit,5
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
价 格:¥电议型 号:T8357产 地:中国大陆
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T9941STK414603STK414603
STK414603 is a heterocyclic acetamide derivative with potential analgesic, anti-inflammatory, and antimicrobial activities.
价 格:¥电议型 号:T9941产 地:中国大陆
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T6846VesatolimodHepatitis B virus,Vesatolimod,HCV,inhibit,Apoptosis,GS9620,Human immunodeficiency virus,G
GS-9620 is an effective and specific orally active agonist of Toll-like receptor 7.
价 格:¥电议型 号:T6846产 地:中国大陆
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TMS1461Qingyangshengenin BAmyloid-β,Abeta,Inhibitor,Qingyangshengenin B,β-amyloid peptide,inhibit
Qingyangshengenin B is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer´s disease. Otophylloside B can suppress the seizure-like locomotor act
价 格:¥电议型 号:TMS1461产 地:中国大陆
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T9246JNJ-63576253TRC-253,mutant,JNJ 63576253,resistant,wild-type,JNJ63576253,TRC 253,prostate,inhibit,And
JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).
价 格:¥电议型 号:T9246产 地:中国大陆
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T8546BD750Immunosuppressant,JAK,BD750,cell,Janus kinase,BD-750,inhibit,STAT,Inhibitor,BD 750
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)
价 格:¥电议型 号:T8546产 地:中国大陆
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TP1403LSyntide 2 acetate(108334-68-5 free base)Syntide 2 acetate(108334685 free base),Syntide 2 acetate(108
Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).
价 格:¥电议型 号:TP1403L产 地:中国大陆
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T8466BC-DXI-843Inhibitor,lung,A549,BCDXI843,AIMP2-DX2,cancer,inhibit,BC DXI 843
BC-DXI-843 is inhibitor of AIMP2-DX2, and is potential for development of novel therapeutics targeting AIMP2-DX2 in lung cancer.
价 格:¥电议型 号:T8466产 地:中国大陆
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T14613BIP-135BIP 135,BIP135
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor. With IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect[1].
价 格:¥电议型 号:T14613产 地:中国大陆
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T14671BMS-193885BMS193885,BMS 193885
BMS-193885 is a selective, brain-penetrant, and competitive antagonist of the neuropeptide Y1 receptor with a Ki of 3.3 nM, and an IC50 of 5.9 nM for hY1.
价 格:¥电议型 号:T14671产 地:中国大陆