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  • T76471Lactoferricin, bovine；化合物 Lactoferricin, bovineLactoferricin, bovine

    Lactoferricin, bovine is an iron-binding glycoprotein derived from the acidic hydrolysis of bovine lactoferrin. Lactoferricin, bovine has bactericidal, antifungal, antiparasitic, antitumor, antiviral, and immunomodulatory activities [1] .

    价 格：￥电议型 号：T76471产 地：中国大陆

  • T75471Chetoseminudin B；化合物 Chetoseminudin BChetoseminudin B

    Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].

    价 格：￥电议型 号：T75471产 地：中国大陆

  • T74718STING modulator-5；化合物 STING modulator-5STING modulator-5

    STING modulator-5 (compound 38), a STING modulator, exhibits a pIC50 value of 9.5 and antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. Additionally, it acts as an antagonist of THP-1 cells, making it applicable in immunological disease research [1].

    价 格：￥电议型 号：T74718产 地：中国大陆

  • T7471712-Hydroxynevirapine；化合物 12-Hydroxynevirapine12-Hydroxynevirapine

    12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP), a significant oxidative metabolite of Nevirapine—an antiviral drug used for HIV-1 infections known for potential idiosyncratic hepatotoxicity and skin rashes—undergoes bioactivation through sulphotransferases (SULTs) in the liver and skin to form the reactive species 12-Sulphoxy-nevirapine [1] [2].

    价 格：￥电议型 号：T74717产 地：中国大陆

  • T74716Curcumin 5-8；化合物 Curcumin 5-8Curcumin 5-8

    Curcumin 5-8 (CUR5-8), a naturally active analog of curcumin (CUR), exhibits potent oral activity. It effectively inhibits lipid droplet formation, enhances autophagy, and reduces apoptosis. Additionally, Curcumin 5-8 has been shown to ameliorate insulin resistance and enhance insulin sensitivity [1].

    价 格：￥电议型 号：T74716产 地：中国大陆

  • T74715Antibacterial agent 136；化合物 Antibacterial agent 136Antibacterial agent 136

    Antibacterial Agent 136 (Compound 3), an oxadiazolone antibiotic, exhibits high antibacterial potency against Methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) 50 value of 0.8 μM [1].

    价 格：￥电议型 号：T74715产 地：中国大陆

  • T74714TP0597850；化合物 TP0597850TP0597850

    TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].

    价 格：￥电议型 号：T74714产 地：中国大陆

  • T74713TMV-IN-3；化合物 TMV-IN-3TMV-IN-3

    TMV-IN-3, a chalcone derivative, functions as a tobacco mosaic virus (TMV) inhibitor, exhibiting antiviral activity against TMV with an EC50 of 120.3 μg/mL. This compound is applicable for research in infection, inflammation, and tumor [1].

    价 格：￥电议型 号：T74713产 地：中国大陆

  • T74712TMV-IN-2；化合物 TMV-IN-2TMV-IN-2

    TMV-IN-2, a chalcone derivative, functions as an inhibitor of the tobacco mosaic virus (TMV), exhibiting antiviral properties with an EC50 of 89.9 μg/mL. This compound is utilized in investigating infection, inflammation, and tumor research [1].

    价 格：￥电议型 号：T74712产 地：中国大陆

  • T74711p-HTAA；化合物 p-HTAAp-HTAA

    Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].

    价 格：￥电议型 号：T74711产 地：中国大陆

  • T74710YX-2-107；化合物YX-2-107YX-2-107

    YX-2-107 is a selective and potent CDK6-degrading PROTAC with an IC50 value of 4.4 nM.YX-2-107 inhibits RB phosphorylation and FOXM1 expression in vitro, and inhibits the development of Ph+ ALL in rats.YX-2-107 can be used for the prophylaxis and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). YX-2-107 can be used for the prevention and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

    价 格：￥电议型 号：T74710产 地：中国大陆

  • T74471m7GpppAmpG；化合物 m7GpppAmpGm7GpppAmpG

    M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].

    价 格：￥电议型 号：T74471产 地：中国大陆

  • T7359CAY10471 Racemate；化合物CAY10471 RacemateTM30089 Racemate；TM30089 Racemate|||3-[[(4-氟苯基)磺酰基]甲基氨基]-1,2,3

    CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and >10,000 nM,respectively)

    价 格：￥电议型 号：T7359产 地：中国大陆

  • T73471YLT-11；化合物 YLT-11YLT-11

    YLT-11 is a potent, selective, and orally active inhibitor of polo-like kinase 4 (PLK4), exhibiting dissociation constant (Kd) values of >10000 nM for PLK1, 653 nM for PLK2, >10000 nM for PLK3, and 5.2 nM for PLK4, respectively. It demonstrates antiproliferative effects, induces apoptosis, and causes cell cycle arrest at the G2/M phase, highlighting its anticancer activity.

    价 格：￥电议型 号：T73471产 地：中国大陆

  • T73453MRS4719；化合物 MRS4719MRS4719

    MRS4719, a potent P2X4 receptor antagonist, exhibits a half-maximal inhibitory concentration (IC50) of 0.503 μM for the human P2X4 receptor. Demonstrating both neuroprotective and neuro-rehabilitative effects, it can decrease infarct volume and brain atrophy in an ischemic stroke model. Additionally, MRS4719 mitigates ATP-induced calcium influx in primary human monocyte-derived macrophages, making it a valuable tool for researching ischemic stroke.

    价 格：￥电议型 号：T73453产 地：中国大陆

  • T73433MS47134；化合物 MS47134MS47134

    MS47134, a selective and potent MRGPRX4 agonist, exhibits an EC50 of 149 nM and holds potential for researching pain, itch, and mast cell-mediated hypersensitivity.

    价 格：￥电议型 号：T73433产 地：中国大陆

  • T73420SP-471P；化合物 SP-471PSP-471P

    SP-471P is a potent inhibitor of dengue virus (DENV) protease, exhibiting half-maximal effective concentrations (EC50) of 5.9 μM for DENV1, 1.4 μM for DENV2, 5.1 μM for DENV3, and 1.7 μM for DENV4, with a cytotoxic concentration (CC50) greater than 100 μM. Additionally, SP-471P effectively reduces DENV viral RNA synthesis [1].

    价 格：￥电议型 号：T73420产 地：中国大陆

  • T72471Antioxidant agent-2；化合物 Antioxidant agent-2Antioxidant agent-2

    Antioxidant agent-2 (comp 3c), a BBB-penetrating and selective metal ion chelator, exhibits significant neuroprotective and hepatoprotective effects, making it beneficial for Alzheimer’s disease research.

    价 格：￥电议型 号：T72471产 地：中国大陆

  • T71665INCB-9471；化合物 INCB-9471INCB-9471

    INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.

    价 格：￥电议型 号：T71665产 地：中国大陆

  • T71471Chrysotobibenzyl；化合物 ChrysotobibenzylChrysotobibenzyl

    Chrysotobibenzyl, a bibenzyl found in the stem of Dendrobium pulchellum, may facilitate anoikis--a form of programmed cell death that occurs in anchorage-dependent cells when they detach from the surrounding extracellular matrix (ECM)-- and inhibit the growth of lung cancer cells in anchorage-independent condition. Preliminary data obtained discloses the inhibitory effect on cancer cell metastasis of the isolated compounds and may provide a new approach for cancer drug development.

    价 格：￥电议型 号：T71471产 地：中国大陆

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