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  • T80492Mambalgin-2；化合物 Mambalgin-2Mamb-2；Mamb-2

    Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs). It is utilized in research focused on pain and neurological diseases [1].

    价 格：￥电议型 号：T80492产 地：中国大陆

  • T79492h-NTPDase8-IN-1；h-NTPDase8 抑制剂 1h-NTPDase8-IN-1

    h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8 (IC 50 = 0.28 ± 0.07 μM). h-NTPDase8-IN-1 can be used to study diseases brought about by aberrant h -NTPDase expression.

    价 格：￥电议型 号：T79492产 地：中国大陆

  • T78492D-Mannuronic acid sodium；D-甘露糖醛酸单糖D-Mannuronic acid sodium

    Sodium D-mannuronate, derived from the seaweed Macrocystis pyrifera, shows promise as a therapeutic agent in studies of autoimmune encephalomyelitis (EAE), adjuvant-induced arthritis (AIA), nephrotic syndrome, and acute glomerulonephritis [1].

    价 格：￥电议型 号：T78492产 地：中国大陆

  • T76492(Tyr0)-Urocortin, rat；化合物 (Tyr0)-Urocortin, rat(Tyr0)-Urocortin, rat

    (Tyr0)-Urocortin, rat, serves as a high-affinity agonist for both corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2), demonstrating inhibitory binding constants (Ki) of 1-2 nM [1].

    价 格：￥电议型 号：T76492产 地：中国大陆

  • T7561Benzetimide hydrochloride盐酸苄替米特盐酸苄替米特|||R4929

    Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.

    价 格：￥电议型 号：T7561产 地：中国大陆

  • T75492Ellipyrone A；化合物 Ellipyrone AEllipyrone A

    Ellipyrone A, a γ-pyrone-based macrocyclic polyketide, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50 = 0.35 mM). Additionally, this compound exhibits anti-glycolytic effects on α-glucosidase (IC 50 = 0.74 mM) and α-amylase (IC 50 = 0.59 mM) [1].

    价 格：￥电议型 号：T75492产 地：中国大陆

  • T75133NRX-0492；化合物 NRX-0492NRX-0492

    NRX-0492 is an orally administered compound that efficiently degrades Bruton´s tyrosine kinase (BTK) by catalyzing its ubiquitylation and subsequent proteasomal degradation, achieving half-maximal degradation concentrations (DC50) of ≤0.2 nM and 90% degradation concentrations (DC90) of ≤0.5 nM. Additionally, NRX-0492 suppresses B-cell receptor (BCR) signaling, transcriptional activities, and chemokine production by linking a noncovalent BTK-binding domain to Cereblon, an adaptor protein wi

    价 格：￥电议型 号：T75133产 地：中国大陆

  • T74929Phytoene desaturase-IN-1；化合物 Phytoene desaturase-IN-1Phytoene desaturase-IN-1

    Phytoene desaturase-IN-1, a potent inhibitor of phytoene desaturase (PDS) with a dissociation constant (Kd) of 65.9 μM, acts through π?π stacking interaction with the Phe301 residue. This compound exhibits a broad spectrum of post-emergence herbicidal effects by inducing a reduction in PDS mRNA, and accumulation of phytoene and reactive oxygen species (ROS) in albino leaves, suggesting its utility in agricultural production [1].

    价 格：￥电议型 号：T74929产 地：中国大陆

  • T74923ICy-Q；化合物 ICy-QICy-Q

    ICy-Q, a near-infrared (NIR) reagent activated by quinone oxidoreductase 1 (NQO-1), interacts with NQO-1 to yield the reduced product ICy-OH. This derivative selectively triggers pyroptosis and resultant death in pancreatic cancer cells. Moreover, ICy-Q serves as a valuable instrument for the expedited and precise diagnosis of intraoperative pathological sections [1].

    价 格：￥电议型 号：T74923产 地：中国大陆

  • T74922ICy-OH；化合物 ICy-OHICy-OH

    ICy-OH, a iodinated photosensitizer, serves as a potent anticancer agent, capable of deep tissue imaging (λ ex =640 nm, λ em =690-740 nm) and selectively triggering cell death in pancreatic cancer cells through the cell pyroptosis pathway [1].

    价 格：￥电议型 号：T74922产 地：中国大陆

  • T74921Antiproliferative agent-12；化合物 Antiproliferative agent-12Antiproliferative agent-12

    Antiproliferative Agent-10 (Compound 1), a ruthenium(II)-tris-pyrazolylmethane complex, functions as an anti-tumor agent by impeding cancer cell proliferation through the inhibition of mitochondrial calcium uptake [1].

    价 格：￥电议型 号：T74921产 地：中国大陆

  • T74920G12Si-2；化合物 G12Si-2G12Si-2

    G12Si-2, an analog of G12Si-1 , is a negative control tool. G12Si-2 is not a covalent inhibitor of the G12S mutant of K-Ras [1] .

    价 格：￥电议型 号：T74920产 地：中国大陆

  • T7492Ripasudil free base；化合物Ripasudil free baseK-115 (free base)；K-115 (free base)

    Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.

    价 格：￥电议型 号：T7492产 地：中国大陆

  • T74492CD22 ligand-1；化合物 CD22 ligand-1CD22 ligand-1

    CD22 Ligand-1 (Compound 12) is a potent, selective ligand for CD22, exhibiting dissociation constants (K_D) of 0.335 ?M for human CD22 (hCD22) and 30.7 ?M for myelin-associated glycoprotein (MAG), indicating specificity towards hCD22. This ligand holds potential for B-cell related disease research [1].

    价 格：￥电议型 号：T74492产 地：中国大陆

  • T74185(S,S)-BMS-984923；化合物 (S,S)-BMS-984923(S,S)-BMS-984923

    (S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC 50 >1μM for mGluR5 receptor [1] . BMS-984923 is a potent mGluR5 silent allosteric modulator [2] .

    价 格：￥电议型 号：T74185产 地：中国大陆

  • T73492AB-836；化合物 AB-836AB-836

    AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.

    价 格：￥电议型 号：T73492产 地：中国大陆

  • T72809(S)-Renzapride；化合物 (S)-Renzapride(S)-BRL 24924；(S)-BRL 24924

    (S)-Renzapride ((S)-BRL 24924), an isomer of Renzapride, acts as a 5-HT4 receptor agonist with a K_i value of 115 nM and also antagonizes 5HT2b and 5HT3 receptors. It is utilized in studies focused on constipation-predominant irritable bowel syndrome (C-IBS).

    价 格：￥电议型 号：T72809产 地：中国大陆

  • T72492GnRH-R antagonist 1；化合物 GnRH-R antagonist 1GnRH-R antagonist 1

    GnRH-R antagonist 1 (Compound 21a), is an orally active, membrane-permeable agent with a high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic efficacy (IC50=2.18 nM). It is utilized in research focused on advanced prostate cancer and the prevention of premature LH surges [1].

    价 格：￥电议型 号：T72492产 地：中国大陆

  • T71492Atorvastatin strontium；化合物 Atorvastatin strontiumAtorvastatin strontium

    Atorvastatin strontium is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.

    价 格：￥电议型 号：T71492产 地：中国大陆

  • T70492DOOT-2d；化合物 DOOT-2dDOOT-2d

    DOOT-2d is a selective MAO-B inhibitor.

    价 格：￥电议型 号：T70492产 地：中国大陆

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