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T75152ARC19499;化合物 ARC19499ARC19499
ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor Xa and the TF/factor VIIa complex, thereby correcting thrombin generation in hemophilia A and B plasma and restoring clotting in FVIII-neutralized whole blood.
价 格:¥电议型 号:T75152产 地:中国大陆
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T75151Aganirsen;化合物 AganirsenAganirsen
Aganirsen, a 25-mer DNA antisense oligonucleotide, silences the expression of insulin receptor substrate-1 (IRS-1).
价 格:¥电议型 号:T75151产 地:中国大陆
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T75150GIP/GLP-1 dual receptor agonist-1;化合物 GIP/GLP-1 dual receptor agonist-1GIP/GLP-1 dual receptor agoni
GIP/GLP-1 dual receptor agonist-1 (compound 4), a receptor agonist for both GIP and GLP-1, shows potential for the research of metabolic disorders and fatty liver diseases, such as nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) [1].
价 格:¥电议型 号:T75150产 地:中国大陆
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T7515MTEP hydrochloride;3-[2-(2-甲基-4-噻唑基)乙炔基]吡啶盐酸盐3-((2-Methyl-1,3-thiazol-4-yl)ethyn-yl)pyridine hydroch
MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)
价 格:¥电议型 号:T7515产 地:中国大陆
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T74515PROTAC EGFR degrader 4;化合物 PROTAC EGFR degrader 4PROTAC EGFR degrader 4
PROTAC EGFR degrader 4 is a potent molecule designed to target and degrade mutant EGFR, showcasing its effectiveness by inducing degradation of EGFR del19 and EGFR L858R/T790M with DC50 values of 0.51 nM and 126 nM, respectively. Furthermore, it significantly inhibits the growth of HCC827 and H1975 cell lines, demonstrating IC50 values of 0.83 nM and 203.1 nM, respectively. The induced degradation of EGFR by this compound is associated with autophagy [1].
价 格:¥电议型 号:T74515产 地:中国大陆
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T73515MC2590;化合物 MC2590MC2590
MC2590 is a potent and selective histone deacetylase (HDAC) inhibitor that inhibits HDAC1-3, -6, -8, and -10 activities, induces cell cycle arrest, and promotes apoptosis.
价 格:¥电议型 号:T73515产 地:中国大陆
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T72515Elobixibat hydrate;化合物 Elobixibat hydrateA 3309 hydrate ; AZD 7806 hydrate|||AZD 7806 hydrate|||A 3
Elobixibat hydrate, a potent inhibitor of the ileal bile acid transporter (IBAT), exhibits IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human, mouse, and canine IBAT, respectively. It is utilized in the research of chronic idiopathic constipation (CIC).
价 格:¥电议型 号:T72515产 地:中国大陆
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T72217Altretamine hydrochloride;化合物 Altretamine hydrochlorideRB-1515 hydrochloride|||ENT-50852 hydrochlori
Altretamine hydrochloride is an alkylating antineoplastic agent.
价 格:¥电议型 号:T72217产 地:中国大陆
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T7163PF-05175157;化合物PF 05175157PF-05175157
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively
价 格:¥电议型 号:T7163产 地:中国大陆
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T71515RhlR Antagonist E22;化合物 RhlR Antagonist E22RhlR Antagonist E22
RhlR antagonist E22 is a quorum sensing modulator as an RhlR antagonist.
价 格:¥电议型 号:T71515产 地:中国大陆
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T71166PF-05150122;化合物 PF-05150122PF-05150122
PF-05150122 is a novel potent and selective human Nav1.7 blocker.
价 格:¥电议型 号:T71166产 地:中国大陆
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T70617GP-1-515;化合物 GP-1-515GP-1-515
GP-1-515 is an adenosine kinase inhibitor with anti-inflammatory effects.
价 格:¥电议型 号:T70617产 地:中国大陆
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T70515Canventol;化合物 CanventolCanventol
Canventol inhibits tumor necrosis factor alpha release and protein isoprenylation
价 格:¥电议型 号:T70515产 地:中国大陆
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T70412PNU-145156E free base;化合物 PNU-145156E free basePNU-145156E free base
PNU-145156E free base is an angiogenesis inhibitor.
价 格:¥电议型 号:T70412产 地:中国大陆
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T70137CAM 4515;化合物 CAM 4515CAM 4515
CAM 4515 is a nonpeptide tachykinin NK1 receptor antagonist.
价 格:¥电议型 号:T70137产 地:中国大陆
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T69790GW-475151;化合物 GW-475151GW-475151
GW-475151 inhibits human neutrophil elastase (HNE).
价 格:¥电议型 号:T69790产 地:中国大陆
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T69515R 101933;化合物 R 101933R 101933
R 101933 is a P-glycoprotein (P-gp) inhibitor.
价 格:¥电议型 号:T69515产 地:中国大陆
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T68515AZD-1175;化合物 AZD-1175AZD-1175
AZD-1175 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes and obesity.
价 格:¥电议型 号:T68515产 地:中国大陆
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T67515(R)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid hydrate;化合物 (R)-2-((tert-Butoxycarbonyl)am
(R)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid hydrate is a useful organic compound for research related to life sciences. The catalog number is T67515 and the CAS number is 200937-17-3.
价 格:¥电议型 号:T67515产 地:中国大陆