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T16376Odevixibat
Odevixibat is an effective, selective and orally active ileal bile acid transporter inhibitor. Odevixibat has the potential for the treatment of primary biliary cirrhosis. Odevixibat reduces cholestatic liver and bile duct injury in mice model.
价 格:¥电议型 号:T16376产 地:中国大陆
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T4444A-674563 HCl (552325-73-2(free base))A 674563 HCl (552325 73 2(free base)),A674563 HCl (552325732(fr
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in the CMGC, CAMK, and TK families [1].
价 格:¥电议型 号:T4444产 地:中国大陆
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T9852MUN36378MUN36378
MUN36378 is a FTO inhibitor for treatment of leukemia.
价 格:¥电议型 号:T9852产 地:中国大陆
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T9863PKCiota-IN-2
PKCiota-IN-2 is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively
价 格:¥电议型 号:T9863产 地:中国大陆
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T7497LC3a 70-77 2TFA(63555-63-5(free base))C3a 70 77 2TFA(63555 63 5(free base)),C3a 7077 2TFA(63555635(fr
C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a.
价 格:¥电议型 号:T7497L产 地:中国大陆
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T6636RefametinibMEK1,allosteric,RDEA 119,BAY-869766,inhibit,Inhibitor,MAP2K,MEK2,orally,MAPKK,RDEA-119,Mi
Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).
价 格:¥电议型 号:T6636产 地:中国大陆
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T7636Phenprocoumoninhibit,Phenprocoumon,Inhibitor
Phenprocoumon is an antagonist of vitamin K(IC50:1 μM).
价 格:¥电议型 号:T7636产 地:中国大陆
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TP1186Cyclo(Phe-Pro)inhibit,Cyclo(Phe Pro),Inhibitor,Cyclo(PhePro),A64863,A 64863,Cyclo(Phe-Pro)
Cyclo(Phe-Pro) known as a secondary metabolite of some bacteria and fungi, is also produced by Vibrio vulnificus.
价 格:¥电议型 号:TP1186产 地:中国大陆
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T16771RO-5963RO5963,RO 5963
RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).
价 格:¥电议型 号:T16771产 地:中国大陆
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T6748A-1155463Bcl-2 Family,Inhibitor,A-1155463,inhibit
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
价 格:¥电议型 号:T6748产 地:中国大陆
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T6388AmprenavirHIV,SARS coronavirus,Inhibitor,VX478,HIV Protease,SARS-CoV,VX 478,inhibit,Amprenavir,Human
Amprenavir is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
价 格:¥电议型 号:T6388产 地:中国大陆
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T6811CPI-637Inhibitor,inhibit,HAT,Epigenetic Reader Domain,CPI637,CPI-637,Histone Acetyltransferase,HATs
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.
价 格:¥电议型 号:T6811产 地:中国大陆
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T63536Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T60487DDO-7263
DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 is a potent Nrf2 activator that activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity [1].
价 格:¥电议型 号:T60487产 地:中国大陆
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T6376Allopurinol Sodiumanti-nociception,HIF-2α,inhibit,anti-leishmanial,gout,hyperuricemia,HIF-1α,HUVEC c
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
价 格:¥电议型 号:T6376产 地:中国大陆
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T9003CVT-11127Inhibitor,apoposis,GS 456332,S-phase,monounsaturated fatty acids (MUFA),Stearoyl-CoA Desatu
CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
价 格:¥电议型 号:T9003产 地:中国大陆
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T9632WAY-383487WAY383487,WAY 383487
WAY-383487 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.
价 格:¥电议型 号:T9632产 地:中国大陆
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T63581-AzakenpaulloneGlycogen synthase kinase-3,1 Azakenpaullone,GSK-3,1-Azakenpaullone,1Azakenpaullone,G
1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
价 格:¥电议型 号:T6358产 地:中国大陆
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T6631Quinine hydrochloride dihydrateQuinine hydrochloride dihydrate,inhibit,anti-malarial,cinchonaine,Inh
Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.
价 格:¥电议型 号:T6631产 地:中国大陆
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TP2334PMX 53 acetate(219639-75-5 free base)PMX 53 acetate(219639755 free base),PMX 53 acetate(219639 75 5
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).
价 格:¥电议型 号:TP2334产 地:中国大陆