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产品数:86101
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T6479Dovitinib lactate hydrateVEGFR1,FGFR1,TKI258 lactate,SCFR,CD117,Dovitinib lactate hydrate,FGFR,Fms l
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
价 格:¥电议型 号:T6479产 地:中国大陆
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T36442L(Hyp?)-Bradykinin acetate
(Hyp?)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts.
价 格:¥电议型 号:T36442L产 地:中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格:¥电议型 号:T6481产 地:中国大陆
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T6473DioscinAutophagy,CCRIS-4123,CCRIS4123,Apoptosis,Dioscin,inhibit,Inhibitor
Dioscin is a saponin with antitumor activities.
价 格:¥电议型 号:T6473产 地:中国大陆
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T16491PF-06446846 hydrochloridePF06446846 hydrochloride,PF 06446846 hydrochloride
PF-06446846 hydrochloride suppresses PCSK9 by inducing the ribosome to stall around codon 34. PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9.
价 格:¥电议型 号:T16491产 地:中国大陆
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T8464RA-9Unfolded,RA-9,cancer,RA 9,DUBs,Inhibitor,Apoptosis,Response,Deubiquitinase,cells,inhibit,Protein
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.
价 格:¥电议型 号:T8464产 地:中国大陆
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T64373CDK1-IN-2
CDK1-IN-2 is a CDK1 inhibitor with IC50 of 5.8 μM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases.
价 格:¥电议型 号:T64373产 地:中国大陆
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TN7064CandicineCandicine
Candicine is a natural product from Stapelia gigantea.
价 格:¥电议型 号:TN7064产 地:中国大陆
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T36640Xanomeline
Xanomeline is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials. Xanomeline is well absorbed orally, crosses the blood-brain barrier and undergoes extensive liver metabolism with at least six metabolites.
价 格:¥电议型 号:T36640产 地:中国大陆
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T64376WAY-652509WAY652509
WAY-652509 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.
价 格:¥电议型 号:T64376产 地:中国大陆
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T6445CilomilastCilomilast,asthma,immunomodulatory,obstructive,Inhibitor,Phosphodiesterase (PDE),inhibit,P
Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.
价 格:¥电议型 号:T6445产 地:中国大陆
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T6461Dapoxetine hydrochlorideBenign,BPH,serotonin reuptake,SERT,sexual disorder,LY210448,SLC6A4,Dapoxetin
Dapoxetine HCl is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
价 格:¥电议型 号:T6461产 地:中国大陆
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T8961GW280264XGW-280264X,inhibit,GIC,Inhibitor,immunotherapy,metalloproteinases,Matrix metalloproteinases
GW280264X is an inhibitor of ADAM17 .
价 格:¥电议型 号:T8961产 地:中国大陆
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TN6864Prosaikogenin Finhibit,Prosaikogenin F,monoglycoside,Inhibitor,hemolytic,corticosterone,anticancer
Prosaikogenin F is a natural product with anticancer and hemolytic properties [1].
价 格:¥电议型 号:TN6864产 地:中国大陆
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T6496Vactosertibantimetastatic,invasion,Smad,TEW7197,Transforming growth factor beta receptors,TGFβ,migra
Vactosertib is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potential antineoplastic activity.
价 格:¥电议型 号:T6496产 地:中国大陆
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T6764LATI-2341 acetate(1337878-62-2 free base)ATI2341 acetate(1337878622 free base),ATI 2341 acetate(13378
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization.
价 格:¥电议型 号:T6764L产 地:中国大陆
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T6430CalcifediolVitamin D receptor,Calcifediol,VD/VDR,Vitamin D,Inhibitor,inhibit,Endogenous Metabolite
Calcifediol(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
价 格:¥电议型 号:T6430产 地:中国大陆
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T6457CTEPMetabotropic glutamate receptors,CTEP,RO4956371,inhibit,mGluR,Inhibitor,RO-4956371
CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.
价 格:¥电议型 号:T6457产 地:中国大陆
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T64344N-Methyl-DL-aspartic acidNMethylDLasparticacid
N-Methyl-DL-aspartic acid is a glutamate analogue and a NMDA receptor agonist and can be used for neurological diseases research.
价 格:¥电议型 号:T64344产 地:中国大陆
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T6434CCG-50014Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,in
CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
价 格:¥电议型 号:T6434产 地:中国大陆