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T10773CF53CF-53,CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格:¥电议型 号:T10773产 地:中国大陆
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T6473DioscinAutophagy,CCRIS-4123,CCRIS4123,Apoptosis,Dioscin,inhibit,Inhibitor
Dioscin is a saponin with antitumor activities.
价 格:¥电议型 号:T6473产 地:中国大陆
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T7305JQEZ5S-adenosyl,EZH2,JQEZ5,antitumor,methionine,JQEZ 5,H3K27me3,PRC2,inhibit,Inhibitor,JQEZ-5,Histon
JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).
价 格:¥电议型 号:T7305产 地:中国大陆
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T6737ZaltoprofenCN-100,anti-inflammatory,COX-2,inhibit,non-steroidal,Zaltoprofen,Inhibitor,COX,NSAID,COX-
Zaltoprofen is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.
价 格:¥电议型 号:T6737产 地:中国大陆
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T64373CDK1-IN-2
CDK1-IN-2 is a CDK1 inhibitor with IC50 of 5.8 μM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases.
价 格:¥电议型 号:T64373产 地:中国大陆
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T7393ONO-7300243ONO7300243,inhibit,Inhibitor,ONO 7300243,ONO-7300243,LPL Receptor,Lysophospholipid Recept
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).
价 格:¥电议型 号:T7393产 地:中国大陆
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T8875CD73-IN-3Inhibitor,cancer,CD73 IN 3,CD-73-IN-3,CD73IN3,CD73,Immunosuppression,tumor,inhibit
LY-3475070 is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
价 格:¥电议型 号:T8875产 地:中国大陆
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T7382NBD-557HIV,NBD557,NBD 557,NBD-557,inhibit,Human immunodeficiency virus,Inhibitor
NBD-557 is a potentially HIV-1 inhibitor.
价 格:¥电议型 号:T7382产 地:中国大陆
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TP1127L1Nemifitide acetate(173240-15-8 free base)Nemifitide acetate(173240 15 8 free base),Nemifitide acetat
Nemifitide acetate is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF).
价 格:¥电议型 号:TP1127L1产 地:中国大陆
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TN1731HernandezineHernandezine
Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.
价 格:¥电议型 号:TN1731产 地:中国大陆
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T7173L[Leu5]-Enkephalin acetate(58822-25-6 free base)[Leu5] Enkephalin acetate(58822 25 6 free base),[Leu5
[Leu5]-Enkephalin acetate is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
价 格:¥电议型 号:T7173L产 地:中国大陆
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T7378BRD9539Histone Methyltransferase,chromatin,PRC2,BRD9539,G9a,senescent,BRD-9539,BRD 9539,inhibit,H3K9
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μM
价 格:¥电议型 号:T7378产 地:中国大陆
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T9843WAY-297342WAY 297342,WAY297342
FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia [1].
价 格:¥电议型 号:T9843产 地:中国大陆
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T9029STING-IN-3genes,inhibit,ERIS,TMEM173,mmSTING,Inhibitor,Stimulator of Interferon Genes,STING,MPYS,MIT
C-171 is an inhibitor of stimulator of interferon genes (STING).?It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
价 格:¥电议型 号:T9029产 地:中国大陆
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TN6738Orthosphenic acidOrthosphenic acid
Orthosphenic acid is a natural product isolated from M. triflora.
价 格:¥电议型 号:TN6738产 地:中国大陆
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T6732WYE-687mTOR,Mammalian target of Rapamycin,WYE-687,Phosphoinositide 3-kinase,WYE687,PI3K,WYE 687,inhi
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6732产 地:中国大陆
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T7317CU-CPT-9aToll-like Receptor (TLR),inhibit,Inhibitor,CU CPT 9a,CUCPT9a
CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-
价 格:¥电议型 号:T7317产 地:中国大陆
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T7344SDMAinhibit,Inhibitor,Endogenous Metabolite,SDMA
SDMA is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).
价 格:¥电议型 号:T7344产 地:中国大陆
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TP1773LPGLa acetatePGLa acetate
PGLa acetate is a 21-residue member of the magainin family of antibiotic peptides.
价 格:¥电议型 号:TP1773L产 地:中国大陆