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T7502LPF 05089771Na+ channels,diabetic,inhibit,Inhibitor,neuropathy,Sodium Channel,Na channels,TTX-R,PF 05
PF-05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
价 格：￥电议型 号：T7502L产 地：中国大陆
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T10773CF53CF-53,CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格：￥电议型 号：T10773产 地：中国大陆
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T67729UCM-1306UCM1036
UCM-1306 is a potent and orally active allosteric modulator (PAM) of human dopamine D1 receptor. UCM-1306 could increase the maximal effect of endogenous dopamine (DA) both in human and mouse D1 receptors. UCM-1306 could improve motor symptoms and address the key comorbid cognitive impairment associated with long-term Parkinson’s disease (PD).
价 格：￥电议型 号：T67729产 地：中国大陆
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T7709(E/Z)-GSK5182(E/Z)GSK5182,(E/Z) GSK5182,(E/Z)-GSK-5182
(E/Z)-GSK5182 is a racemate of (E)-GSK5182 and (Z)-GSK5182 isomers. GSK5182 is a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ) with an IC 50 of 79 nM [1]. GSK5182 also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma [1] [2] [3].
价 格：￥电议型 号：T7709产 地：中国大陆
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TCS1772Dehydroabietic acidinhibit,Dehydroabietic acid,Inhibitor
1. Dehydroabietic acid (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma triglyceride (TG) , and hepatic TG levels. 3. DAA derivatives displays anti-secretory and anti-pepsin effect in animal models.
价 格：￥电议型 号：TCS1772产 地：中国大陆
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T15772Lodoxamide tromethamine
Lodoxamide tromethamine is a mast cell stabilizer with anti-allergic properties and can be used in studies about the treatment of asthma and allergic conjunctivitis.
价 格：￥电议型 号：T15772产 地：中国大陆
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T9703LGSK778 hydrochlorideGSK778 hydrochloride
GSK778 hydrochloride hydrochloride is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. GSK778 hydrochloride hydrochloride phenocopies the effects of pan-BET inhibitors in cancer models[1].
价 格：￥电议型 号：T9703L产 地：中国大陆
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T7761Pomalidomide-C2-NH2 hydrochloridePomalidomideC2NH2 hydrochloride,inhibit,Inhibitor,Pomalidomide-C-2-
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-C2-NH2 hydrochloride incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
价 格：￥电议型 号：T7761产 地：中国大陆
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T9877Tiquiziumtiquizium
Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.
价 格：￥电议型 号：T9877产 地：中国大陆
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T6771AZD3264inhibit,I kappa B kinase,IκB kinase,AZD 3264,AZD-3264,AZD3264,IKK,Inhibitor
AZD3264 is a new type IKK2 inhibitor.
价 格：￥电议型 号：T6771产 地：中国大陆
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T12861SB-277011
SB-277011 is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
价 格：￥电议型 号：T12861产 地：中国大陆
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T6364DesfesoterodineMuscarinic acetylcholine receptor,metabolite,PNU-200583,Fesoterodine,PNU200577,inhibi
5-hydroxymethyl tolterodine (PNU 200577) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
价 格：￥电议型 号：T6364产 地：中国大陆
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T22812GRI977143GRI977143,GRI-977143
GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragmentation.
价 格：￥电议型 号：T22812产 地：中国大陆
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T8777Beclometasoneinhibit,Beclometasone,Inhibitor,Glucocorticoid Receptor
BecloMethasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.
价 格：￥电议型 号：T8777产 地：中国大陆
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T7817Aprocitentaninhibit,Endothelin Receptor,ACT132577,Aprocitentan,Inhibitor,ACT 132577
Aprocitentan is ETA and ETB antagonist .
价 格：￥电议型 号：T7817产 地：中国大陆
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TP1773LPGLa acetatePGLa acetate
PGLa acetate is a 21-residue member of the magainin family of antibiotic peptides.
价 格：￥电议型 号：TP1773L产 地：中国大陆
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T67755WAY-312157WAY312157
WAY-312157 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.
价 格：￥电议型 号：T67755产 地：中国大陆
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T27710K6PC-5
K6PC-5, a ceramide derivative, is a sphingosine kinase 1(SPHK1) activator and elicites a rapid transient increase in intracellular calcium levels. K6PC-5 has the potential for skin diseases involving abnormal keratinocyte, and neurodegeneration and virus infection research.
价 格：￥电议型 号：T27710产 地：中国大陆
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T7730AminopterinAminopterin,tetrahydrofolic,inhibit,anticancer,immunosuppressive,acid,Antifolate,leukocyt
Aminopterin is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase
价 格：￥电议型 号：T7730产 地：中国大陆
