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T77099Nimacimab;尼迈西单抗JNJ 2463|||RYI-018;JNJ 2463|||RYI-018
Nimacimab is a recombinant humanized monoclonal antibody. It can improve diabetes and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T77099产 地:中国大陆
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T77098Netakimab;化合物 NetakimabNetakimab
Netakimab, an anti-IL-17 monoclonal antibody, is utilized in the research of ankylosing spondylitis, psoriatic arthritis, and moderate-to-severe plaque psoriasis [1] [2].
价 格:¥电议型 号:T77098产 地:中国大陆
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T77097Nerelimomab;化合物 NerelimomabNerelimomab
Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].
价 格:¥电议型 号:T77097产 地:中国大陆
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T77096Nemvaleukin alfa;化合物 Nemvaleukin alfaNemvaleukin alfa
Nemvaleukin alfa (ALKS 4230) is an IL-2 fusion protein that selectively targets intermediate-affinity IL-2R, serving as an activator of NK and effector T cells. This compound is utilized in cancer research [1] [2] [3].
价 格:¥电议型 号:T77096产 地:中国大陆
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T77095Nebacumab;化合物 NebacumabNebacumab
Nebacumab (HA-1A), a monoclonal antibody, targets the lipid A component of endotoxin and has potential applications in sepsis research [1] [2].
价 格:¥电议型 号:T77095产 地:中国大陆
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T77094Navivumab;化合物 NavivumabNavivumab
Navivumab (CT-P23) is a monoclonal antibody targeting the hemagglutinin HA of the influenza A virus, effectively neutralizing strains H1, H2, H5, and H9 by binding to the HA2 stem fusion domain [1].
价 格:¥电议型 号:T77094产 地:中国大陆
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T77093Theralizumab;Theralizumab单抗TGN1412|||TAB-08|||TABO8;TGN1412|||TAB-08|||TABO8
Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.
价 格:¥电议型 号:T77093产 地:中国大陆
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T77092NadecnemabNadecnemab单抗REGN-5069
Nadecnemab is an IGG4-κantibody targeting GFRA3, a receptor of the glial cell-derived neurotrophic factor family. Nadecnemab can be used for knee osteoarthritis and neurological disorders.
价 格:¥电议型 号:T77092产 地:中国大陆
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T77091Modakafusp alfa;化合物 Modakafusp alfaModakafusp alfa
Modakafusp alfa (TAK-573) is a humanized anti-CD38 IgG4 monoclonal antibody, with 2 attenuated IFNα2b molecules fused to it. This compound is researched for potential use in treating multiple myeloma [1].
价 格:¥电议型 号:T77091产 地:中国大陆
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T77090Mitazalimab;化合物 MitazalimabMitazalimab
Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that exhibits directed activity against tumors. By activating antigen-presenting cells, such as dendritic cells (DC), it triggers the initiation of tumor-reactive T cells. Consequently, Mitazalimab promotes the infiltration and destruction of tumors by tumor-specific T cells and remodels the tumor-infiltrating myeloid microenvironment [1] [2].
价 格:¥电议型 号:T77090产 地:中国大陆
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T7709(E/Z)-GSK5182;化合物GSK5182(Z/E)GSK5182(Z/E);GSK5182(Z/E)
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.
价 格:¥电议型 号:T7709产 地:中国大陆
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T77089Mirococept;化合物 MirococeptMirococept
Mirococept (APT070), an antibody designed to target the complement system components C3b/C4b and act as a membrane-localizing C3 convertase inhibitor, effectively diminishes the release of C-peptide and pro-inflammatory cytokines. It also curtails the infiltration of inflammatory cells and intraislet inflammation, offering advantages for islet transplantation. Furthermore, Mirococept mitigates increased vascular permeability in intestinal and pulmonary contexts, thereby reducing neutrophil influ
价 格:¥电议型 号:T77089产 地:中国大陆
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T77088Mirikizumab;化合物 MirikizumabMirikizumab
Mirikizumab (LY3074828), a humanized IgG4 monoclonal antibody, specifically targets the p19 subunit of interleukin 23. It is currently under research for its potential application in treating ulcerative colitis [1].
价 格:¥电议型 号:T77088产 地:中国大陆
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T77087Mipeginterferon alfa-2b;化合物 Mipeginterferon alfa-2bMipeginterferon alfa-2b
Mipeginterferon alfa-2b, an analog of interferon alpha-2b (IFNA2B), features an average substitution of 5 among its 11 amino groups (one N-terminal and 10 lysine N6), and exhibits a relative molecular mass of 40 kDa [1].
价 格:¥电议型 号:T77087产 地:中国大陆
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T77086Mipasetamab uzoptirine;化合物 Mipasetamab uzoptirineMipasetamab uzoptirine
Mipasetamab uzoptirine (ADCT-601) is an antibody-drug conjugate (ADC) targeting AXL. It combines a humanized anti-AXL antibody with a cleavable linker and the potent pyrrolobenzodiazepine (PBD) dimer cytotoxin SG3199. Mipasetamab uzoptirine is utilized in cancer research [1].
价 格:¥电议型 号:T77086产 地:中国大陆
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T77085Mipasetamab;化合物 MipasetamabMipasetamab
Mipasetamab, an IgG1κ antibody, targets AXL, a tyrosine kinase receptor and TAM Receptor. It plays a crucial role in synthesizing ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC), known for its anti-tumor activity [1].
价 格:¥电议型 号:T77085产 地:中国大陆
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T77084Mezagitamab;化合物 MezagitamabMezagitamab
Mezagitamab (TAK-079), an IgG1λ anti-CD38 monoclonal antibody, functions by depleting tumor cells that express CD38 through both antibody and complement-dependent cytotoxicity. It shows potential for use in the treatment of relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) [1] [2] [3].
价 格:¥电议型 号:T77084产 地:中国大陆
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T77083Melrilimab;化合物 MelrilimabMelrilimab
Melrilimab (GSK 3772847), an IgG2-kappa monoclonal antibody targeting IL1RL1/ST2/IL33R/DER4/FIT-1, is utilized in asthma research [1].
价 格:¥电议型 号:T77083产 地:中国大陆
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T77082Melredableukin alfa;化合物 Melredableukin alfaMelredableukin alfa
Melredableukin alfa (RO-7049665) is a fusion protein comprising a human IgG1-κ and a mutated human interleukin 2 (IL2 mutein) connected by a peptide linker, researched for potential applications in autoimmune hepatitis and ulcerative colitis [1].
价 格:¥电议型 号:T77082产 地:中国大陆
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T77081Mazorelvimab;化合物 MazorelvimabMazorelvimab
Mazorelvimab (SYN023), a cocktail composed of the humanized monoclonal antibodies CTB011 and CTB012, targets the rabies virus (RABV) by binding to non-overlapping epitopes on the RABV´s glycoprotein (G). This interaction showcases Mazorelvimab´s potential in rabies prevention [1] [2].
价 格:¥电议型 号:T77081产 地:中国大陆