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  • T73873c-di-AMP disodium；化合物 c-di-AMP disodiumc-di-AMP disodium

    Cyclic diadenylate (c-di-AMP) sodium functions as a STING agonist by binding to the STING transmembrane protein, thus activating the TBK3-IRF3 signaling pathway. This activation prompts the production of type I IFN and TNF. Additionally, c-di-AMP sodium serves as a bacterial second messenger in Gram-positive bacteria, where it plays crucial roles in regulating cell growth, survival, and virulence, as well as the host immune response. It also acts as a potent mucosal adjuvant by stimulating both

    价 格：￥电议型 号：T73873产 地：中国大陆

  • T71873Temechine hydrobromide；化合物 Temechine hydrobromideTemechine hydrobromide

    Temechine hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors.

    价 格：￥电议型 号：T71873产 地：中国大陆

  • T70873M3541；化合物M3541M3541

    M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells.

    价 格：￥电议型 号：T70873产 地：中国大陆

  • T70658Ici D8731；化合物 Ici D8731Ici D8731

    Ici D8731 is a nonpeptide angiotensin II antagonist with potential as a treatment for hypertension and heart failure.

    价 格：￥电议型 号：T70658产 地：中国大陆

  • T69873Cefdinir monohydrate；化合物 Cefdinir monohydrateCefdinir monohydrate

    Cefdinir monohydrate is the salt form of Cefdinir (free base), a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir´s effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of pe

    价 格：￥电议型 号：T69873产 地：中国大陆

  • T6960LPU-H71 HCl；PU-H71盐酸盐PU-H71 HCl(873436-91-0 Free base)|||Zelavespib HCl；PU-H71 HCl(873436-91-0 Free b

    PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.

    价 格：￥电议型 号：T6960L产 地：中国大陆

  • T69563YM-1758735；化合物 YM-1758735YM-1758735

    YM-1758735 is an antagonist.

    价 格：￥电议型 号：T69563产 地：中国大陆

  • T69286IC87361；化合物 IC87361IC87361

    IC87361 is a potent and specific inhibitor of DNA-PK.

    价 格：￥电议型 号：T69286产 地：中国大陆

  • T68873Cornigerine；化合物 CornigerineCornigerine

    Cornigerine is a natural product analog of colchicine produced by Colchicum cornigerum that inhibited tubulin polymerization both with and without microtubule-associated proteins, inhibited the binding of radiolabeled colchicine to tubulin, and stimulated tubulin-dependent GTP hydrolysis.

    价 格：￥电议型 号：T68873产 地：中国大陆

  • T68739Tomoxiprole；化合物 TomoxiproleTomoxiprole

    Tomoxiprole is a cyclooxygenase-2-selective inhibitor.

    价 格：￥电议型 号：T68739产 地：中国大陆

  • T68738(±)-γ-Tocopherol；化合物 (±)-γ-Tocopherol(±)-γ-Tocopherol

    (±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the synthesis of prostaglandin E2 (PGE2) induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells. (±)-γ-Tocopherol inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated

    价 格：￥电议型 号：T68738产 地：中国大陆

  • T68737XR9051；化合物 XR9051XR9051

    XR9051 is as a potent modulator of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) following a synthetic chemistry programme based on a natural product lead compound. XR9051 was shown to be a potent inhibitor of the binding of the cytotoxic to P-glycoprotein (EC50 = 1.4 +/- 0.5 nM). XR9051 reverses the MDR phenotype through direct interaction with P-glycoprotein.

    价 格：￥电议型 号：T68737产 地：中国大陆

  • T68736KU-0058948；化合物 KU-0058948KU-0058948

    KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor that induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro.

    价 格：￥电议型 号：T68736产 地：中国大陆

  • T68735Ciclotropium (free base)；化合物 Ciclotropium (free base)Ciclotropium (free base)

    Ciclotropium (free base) is quaternary ammonium compound with anticholinergic and parasympatholytic activity. Oral Cyclotropium bromide inhibited fasting and meal-stimulated colonic motility significantly without causing adverse side effects. After cyclotropium bromide, there was a significant correlation between antral contraction amplitude and gastric emptying.

    价 格：￥电议型 号：T68735产 地：中国大陆

  • T68734Opc 3911；化合物 Opc 3911Opc 3911

    Opc 3911 is a phosphodiesterase inhibitor.

    价 格：￥电议型 号：T68734产 地：中国大陆

  • T68733Ono 3307 Free Base；化合物 Ono 3307 Free BaseOno 3307 Free Base

    Ono 3307 Free Base is a new synthetic protease inhibitor

    价 格：￥电议型 号：T68733产 地：中国大陆

  • T68732FR-226928 free base；化合物 FR-226928 free baseFR-226928 free base

    FR-226928 free base is a potent antagonist of human neuropeptide Y Y5 receptors.

    价 格：￥电议型 号：T68732产 地：中国大陆

  • T68731Myxothiazol；化合物 MyxothiazolMyxothiazol

    Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation.

    价 格：￥电议型 号：T68731产 地：中国大陆

  • T68730AVE1231；化合物 AVE1231AVE1231

    AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.

    价 格：￥电议型 号：T68730产 地：中国大陆

  • T6873Lauric Acid；月桂酸Dodecylic acid|||dodecanoic acid|||Vulvic acid|||N-Dodecanoic acid；月桂酸|||Dodecylic ac

    Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oil.

    价 格：￥电议型 号：T6873产 地：中国大陆

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