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T78833AJH-836；化合物 AJH-836AJH-836
AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of Munc13-1 from the cytoplasm to the plasma membrane. It is utilized in neurodegenerative disease research [1].
价 格：￥电议型 号：T78833产 地：中国大陆
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T78832FGFR1 inhibitor-9；化合物 FGFR1 inhibitor-9FGFR1 inhibitor-9
FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor with potent binding affinity, exhibiting an IC50 of 0.85 nM. It targets the ATP-binding pocket of FGFR1 and demonstrates anticancer activity [1].
价 格：￥电议型 号：T78832产 地：中国大陆
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T78831FGFR1 inhibitor-8；化合物 FGFR1 inhibitor-8FGFR1 inhibitor-8
FGFR1 inhibitor-8 (Compound 9), an FGFR1 inhibitor with an IC50 of 0.5 nM, binds to the ATP-binding pocket of FGFR1 and exhibits anticancer activity [1].
价 格：￥电议型 号：T78831产 地：中国大陆
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T78830FGFR1 inhibitor 7；化合物 FGFR1 inhibitor 7FGFR1 inhibitor 7
FGFR1 Inhibitor 7 (compound 5), a potent FGFR1 tyrosine kinase inhibitor, exhibits an IC50 of 0.33 nM against its target and demonstrates broad-spectrum cytotoxicity against human cancer cell lines. Additionally, it inhibits MOLT3 cells with an IC50 of 2.1 μM [1].
价 格：￥电议型 号：T78830产 地：中国大陆
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T7883Proanthocyanidins原花青素Procyanidin
Proanthocyanidins is a natural product, used as antioxidant and anti-cancers agent.
价 格：￥电议型 号：T7883产 地：中国大陆
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T78618NSC 288387；化合物 NSC 288387NSC 288387
NSC 288387, a pan-flavivirus MTase inhibitor, binds to the SAM-binding pocket and effectively inhibits Zika virus (ZIKV) with an IC50 of 0.2 μM, also preventing viral replication in cell culture [1].
价 格：￥电议型 号：T78618产 地：中国大陆
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T78558GNE-7883；化合物 GNE-7883GNE-7883
GNE-7883, a pan-TEAD inhibitor, exhibits anti-cell proliferation effects and mitigates resistance to KRAS G12C inhibitors through the inhibition of YAP/TAZ activation in various preclinical models, potentially aiding in the research of YAP/TAZ-dependent cancers [1].
价 格：￥电议型 号：T78558产 地：中国大陆
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T77883Val-Ala-PAB-MMAE；化合物 Val-Ala-PAB-MMAEVal-Ala-PAB-MMAE
Val-Ala-PAB-MMAE is a drug-linker conjugate utilized in antibody-drug conjugates (ADCs), composed of the ADC linker Val-Ala-PAB and the cytotoxic agent monomethyl auristatin E (MMAE), which serves as a potent inhibitor of tubulin.
价 格：￥电议型 号：T77883产 地：中国大陆
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T76883Talacotuzumab；塔妥珠单抗CSL 362|||JNJ 56022473；CSL 362|||JNJ 56022473
Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affinity for CD123, CD32b/c, CD16-158F and CD16-158V, with KD of 0.43 nM, 188 nM, 46 nM and 16.8 nM, respectively. Talacotuzumab inhibits IL-3 signaling in target cells by inhibiting IL-3 binding to CD123. Talacotuzumab induces mutations in the Fc region to increase affinity for CD16 (FCγriiia), thereby enhancing antibody-dependent cell-media
价 格：￥电议型 号：T76883产 地：中国大陆
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T75883Agitoxin-2 TFA；化合物 Agitoxin-2 TFAAgitoxin-2 TFA
Agitoxin-2 TFA, a potent inhibitor of K+ channels, exhibits IC50 values of 201 pM and 144 pM for mK V 1.3 and mK V 1.1, respectively [1] [2].
价 格：￥电议型 号：T75883产 地：中国大陆
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T7567LAdrenorphin 3TFA(88377-68-8(free base))；化合物Adrenorphin 3TFAMetorphamide；Metorphamide
Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) is an agonist of μ-opioid receptor(Ki :12 nM).
价 格：￥电议型 号：T7567L产 地：中国大陆
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T74883DOPE-NHS；化合物 DOPE-NHSDOPE-NHS
DOPE-NHS is a linker useful for conjugating peptides to exosomes and potentially other membrane-based nanoparticles for drug delivery [1].
价 格：￥电议型 号：T74883产 地：中国大陆
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T71883Paraxazone；化合物 ParaxazoneParaxazone
Paraxazone is an antidepressant. It acts as a reversible inhibitor of the enzyme monoamine oxidase.
价 格：￥电议型 号：T71883产 地：中国大陆
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T70883Moexipril-d5；化合物 Moexipril-d5Moexipril-d5
Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 ?M for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 ?M for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day)
价 格：￥电议型 号：T70883产 地：中国大陆
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T70864BMS-883559；化合物 BMS-883559BMS-883559
BMS-883559 is a novel inhibitor of the influenza nucleoprotein (INF-NP).
价 格：￥电议型 号：T70864产 地：中国大陆
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T69883M133；化合物 M133M133
M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.
价 格：￥电议型 号：T69883产 地：中国大陆
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T68883Azafenidin；化合物 AzafenidinAzafenidin
Azafenidin is a EC 1.3.3.4 protoporphyrinogen oxidase inhibitor used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes.
价 格：￥电议型 号：T68883产 地：中国大陆
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T68839CDKi Hydrochloride；化合物 CDKi HydrochlorideCDKi Hydrochloride
CDKi hydrochloride is a potent and selective ATP competitive inhibitor of cycB-CDK1, cycE-CDK2, and cycD1-CDK4.
价 格：￥电议型 号：T68839产 地：中国大陆
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T68838Medroxalol hydrochloride；化合物 Medroxalol hydrochlorideMedroxalol hydrochloride
Medroxalol hydrochloride is an antihypertensive agent that possesses both alpha and beta-adrenergic antagonistic properties.
价 格：￥电议型 号：T68838产 地：中国大陆
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T68837Zelpolib；化合物 ZelpolibZelpolib
Zelpolib is a novel DNA polymerase inhibitor, inhibiting DNA replication in assays to assess global DNA synthesis or single-molecule bases by DNA fiber fluorography.
价 格：￥电议型 号：T68837产 地：中国大陆
