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  • T79053PCSK9-IN-17；化合物 PCSK9-IN-17PCSK9-IN-17

    PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.

    价 格：￥电议型 号：T79053产 地：中国大陆

  • T79052PCSK9-IN-16；化合物 PCSK9-IN-16PCSK9-IN-16

    PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1].

    价 格：￥电议型 号：T79052产 地：中国大陆

  • T79051PCSK9-IN-15；化合物 PCSK9-IN-15PCSK9-IN-15

    PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, K D <200 nM) that plays a crucial role in cholesterol metabolism by regulating blood levels of low-density lipoprotein cholesterol (LDL-C). This compound is useful for researching cholesterol-lowering therapies and dyslipidemia [1].

    价 格：￥电议型 号：T79051产 地：中国大陆

  • T79050JBI-589；化合物 JBI-589JBI-589

    JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1].

    价 格：￥电议型 号：T79050产 地：中国大陆

  • T7905PBD-150；化合物PBD-150PBD-150

    PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)

    价 格：￥电议型 号：T7905产 地：中国大陆

  • T78905AChE-IN-29；化合物 AChE-IN-29AChE-IN-29

    AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric eel acetylcholinesterase (eeAChE), and equine butyrylcholinesterase (eqBChE), exhibiting IC50 values of 0.25 μM, 0.23 μM, and 0.72 μM, respectively. It is utilized in Alzheimer´s disease research [1].

    价 格：￥电议型 号：T78905产 地：中国大陆

  • T78304Bapotulimab；巴泊妥利单抗BAY-1905254；BAY-1905254

    Bapotulimab (BAY-1905254) is a fully human IgG2 antibody that targets the immunoglobulin-like domain-containing receptor 2 (ILDR2), exhibiting antitumor and immunosuppressive effects [1].

    价 格：￥电议型 号：T78304产 地：中国大陆

  • T77905Vobramitamab；化合物 VobramitamabAEX-4089；AEX-4089

    Vobramitamab, a humanized B7-H3 monoclonal antibody (mAb), is conjugated to the prodrug seco-DUBA through a cleavable linker, creating the antibody-drug conjugate (ADC) known as MGC018 [1].

    价 格：￥电议型 号：T77905产 地：中国大陆

  • T76905Anbenitamab；化合物 AnbenitamabAnbenitamab

    Anbenitamab (KN-026) is a bispecific antibody that targets extracellular domains II and IV of human HER2, blocking both ligand-dependent and independent signaling pathways. Its IgG1 Fc fragment activates FcRγIIIa, triggering strong antibody-dependent cell-mediated cytotoxicity (ADCC) and suppressing tumor cell growth. Anbenitamab shows promise for research in HER2-positive metastatic breast cancer (MBC) [1] [2].

    价 格：￥电议型 号：T76905产 地：中国大陆

  • T759052-Furoyl-LIGRLO-amide TFA；化合物 2-Furoyl-LIGRLO-amide TFA2-Furoyl-LIGRLO-amide TFA

    2-Furoyl-LIGRLO-amide TFA is a potent and selective agonist of the proteinase-activated receptor 2 (PAR2), exhibiting a pD2 value of 7.0 [1] [2].

    价 格：￥电议型 号：T75905产 地：中国大陆

  • T74905ODN 2007；化合物 ODN 2007ODN 2007

    ODN 2007, a class B CpG ODN (oligodeoxynucleotide) and Toll-like receptor (TLR) ligand, serves as an immunomodulator and vaccine adjuvant, promoting enhanced immune responses across mammals, fish, and humans. Its sequence is 5´-TCGTCGTTGTCGTTTTGTCGTT-3´ [1] [2] [3].

    价 格：￥电议型 号：T74905产 地：中国大陆

  • T74552Non-PEGylated/naked ARC1905；化合物 Non-PEGylated/naked ARC1905Non-PEGylated/naked ARC1905

    ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched for its potential application in the treatment of age-related macular degeneration (AMD).

    价 格：￥电议型 号：T74552产 地：中国大陆

  • T73905SN-38 glucuronide；化合物 SN-38 glucuronideSN-38 glucuronide

    SN-38 glucuronide, an inactive metabolite of Irinotecan, serves as a derivative of this cancer-fighting agent. Irinotecan, known for inhibiting topoisomerase I, is utilized in the research of colon and rectal cancer [1].

    价 格：￥电议型 号：T73905产 地：中国大陆

  • T72905cyclo(RLsKDK)；化合物 cyclo(RLsKDK)BK-1361；BK-1361

    Cyclo(RLsKDK) (BK-1361) serves as a targeted inhibitor of the metalloproteinase ADAM8, demonstrating efficacy with an IC50 value of 182 nM. This compound shows promise for use in the treatment of inflammatory diseases and cancer, highlighting its potential therapeutic applications.

    价 格：￥电议型 号：T72905产 地：中国大陆

  • T71905BX-513 HCl；化合物 BX-513 HClBX-513 HCl

    BX-513 HCl is a selective CCR1 receptor antagonist.

    价 格：￥电议型 号：T71905产 地：中国大陆

  • T71411U 19052；化合物 U 19052U 19052

    U 19052 is a Leukotriene D4 antagonist.

    价 格：￥电议型 号：T71411产 地：中国大陆

  • T71189RX 809055AX；化合物 RX 809055AXRX 809055AX

    RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.

    价 格：￥电议型 号：T71189产 地：中国大陆

  • T70905TLR9-IN-18；化合物 TLR9-IN-18TLR9-IN-18

    TLR9-IN-18 is a potent and selective TLR9 antagonist. TLR9-IN-18 suppresses the production of the proinflammatory cytokine IL-6 in a CpG-induced mouse model.

    价 格：￥电议型 号：T70905产 地：中国大陆

  • T70776AS-1669058 free base；化合物 AS-1669058 free baseAS-1669058 free base

    AS-1669058 free base is a G-protein-coupled receptor 119 (GPR119) agonist used to as new drug to treat type 2 diabetes.

    价 格：￥电议型 号：T70776产 地：中国大陆

  • T69905Iferanserin HCl；化合物 Iferanserin HClIferanserin HCl

    Iferanserin HCl is a selective serotonin receptor antagonist.

    价 格：￥电议型 号：T69905产 地：中国大陆

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