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T75911[D-Trp34]-Neuropeptide Y TFA;化合物 [D-Trp34]-Neuropeptide Y TFA[D-Trp34]-Neuropeptide Y TFA
[D-Trp34]-Neuropeptide Y TFA acts as a potent and selective agonist for the neuropeptide Y (NPY) Y5 receptor, demonstrating significantly lower potency at the NPY Y1, Y2, Y4, and Y6 receptors. It has been observed to significantly increase food intake in rats [1] [2].
价 格:¥电议型 号:T75911产 地:中国大陆
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T74911ODN 24987;化合物 ODN 24987ODN 24987
ODN 24987, a Guanine-modified inhibitory oligonucleotides (ODN) designed to target TLR9, efficiently suppresses the release of IL-6 and IFN-α, showcasing its potential utility in research on immune disorders. The sequence of ODN 24987 is denoted as 5’-C-C-T-G-G-C-c7G-G-G-G-3’ [1].
价 格:¥电议型 号:T74911产 地:中国大陆
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T7424NDI-091143;化合物NDI-091143NDI-091143
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
价 格:¥电议型 号:T7424产 地:中国大陆
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T73911Antibacterial agent 12;化合物 Antibacterial agent 12Antibacterial agent 12
Antibacterial agent 12, a biaryloxazolidinone analogue, effectively combats both antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria [1].
价 格:¥电议型 号:T73911产 地:中国大陆
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T7369LGemigliptin Tartrate(911637-19-9 free base);吉格列汀酒石酸盐LC15-0444 tartrate;吉格列汀酒石酸盐|||LC15-0444 tartrate
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties.
价 格:¥电议型 号:T7369L产 地:中国大陆
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T7291111β-HSD1-IN-9;化合物 11β-HSD1-IN-911β-HSD1-IN-9
11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 ?M for human and 1.3 ?M for murine variants, respectively. It exhibits competitive interaction with rat 11β-HSD1. This compound holds potential utility in research focused on obesity, hyperglycemia, and cognitive impairment.
价 格:¥电议型 号:T72911产 地:中国大陆
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T7202211β-HSD1 inibitor 19;化合物 11β-HSD1 inibitor 1911β-HSD1 inibitor 19
11β-HSD1 inibitor 19 shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM.
价 格:¥电议型 号:T72022产 地:中国大陆
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T70911PF-5177624;化合物 PF-5177624PF-5177624
PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.
价 格:¥电议型 号:T70911产 地:中国大陆
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T69911CU-6PMN;化合物 CU-6PMNCU-6PMN
CU-6PM is a new fluorescent RXR agonist. CU-6PMN was designed based on the fact that umbelliferone emits strong fluorescence in a hydrophilic environment, but the fluorescence intensity decreases in hydrophobic environments such as the interior of proteins. The developed assay CU-6PMN enabled screening of rexinoids to be performed easily within a few hours by monitoring changes of fluorescence intensity with widely available fluorescence microplate readers, without the needfor processes such as
价 格:¥电议型 号:T69911产 地:中国大陆
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T69119Disopyramide HCl;化合物 Disopyramide HClDisopyramide HCl
Disopyramide HCl is the salt form of Disopyramide, an antiarrhythmic medication used in the treatment of ventricular tachycardia. It is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agent. Disopyramide has a negative inotropic effect on the ventricular myocardium, significantly decreasing the contractility. Disopyramide also has an anticholinergic effect on the heart which accounts for many adverse side effects. Disopyramide is available in both oral and intrave
价 格:¥电议型 号:T69119产 地:中国大陆
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T69117Pinafide;化合物 PinafidePinafide
Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental tumors and shown to be inhibitor of two DNA viruses. Pinafide blocks cell growth by inhibiting DNA and RNA synthesis. It has been shown to bind to double-helical DNA by intercalation. Pinafide inhibited the activity of M. tuberculosis NAD?-dependent DNA ligase A at concentrations
价 格:¥电议型 号:T69117产 地:中国大陆
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T69116Agroclavine;化合物 AgroclavineAgroclavine
Agroclavine is a clavine type of ergot alkaloid with D1 dopamine and a-adrenoceptor agonistic properties.
价 格:¥电议型 号:T69116产 地:中国大陆
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T69115Nutlin-1;化合物 Nutlin-1Nutlin-1
Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.
价 格:¥电议型 号:T69115产 地:中国大陆
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T69114Nutlin-2;化合物 Nutlin-2Nutlin-2
Nutlin-2 is a potent and selective p53-MDM2 binding inhibitor.
价 格:¥电议型 号:T69114产 地:中国大陆
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T69113Nitrofurantoin sodium;化合物 Nitrofurantoin sodiumNitrofurantoin sodium
Nitrofurantoin Sodium is a sodium salt form of nitrofurantoin, a synthetic derivative of imidazolidinedione (hydantoin) that inhibits bacterial DNA, RNA, and cell wall protein synthesis.
价 格:¥电议型 号:T69113产 地:中国大陆
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T69112Pyrvinium chloride;化合物 Pyrvinium chloridePyrvinium chloride
Pyrvinium chloride is used in the treatment of pinworm infections
价 格:¥电议型 号:T69112产 地:中国大陆
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T69110Aseanostatin P5;化合物 Aseanostatin P5Aseanostatin P5
Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes.
价 格:¥电议型 号:T69110产 地:中国大陆
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T6911NSC-87877 disodium;化合物NSC87877NSC87877;NSC87877
NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格:¥电议型 号:T6911产 地:中国大陆