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T64954H-D-Phg(4-Cl)-OH;化合物 H-D-Phg(4-Cl)-OHH-D-Phg(4-Cl)-OH
H-D-Phg(4-Cl)-OH has a wide range of applications in life science related research.
价 格:¥电议型 号:T64954产 地:中国大陆
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T6421BRD73954;化合物BRD73954BRD73954
BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.
价 格:¥电议型 号:T6421产 地:中国大陆
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T63954CYP3A4-IN-1;化合物 CYP3A4-IN-1CYP3A4-IN-1
CYP3A4-IN-1 is a potent inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.085 μM).
价 格:¥电议型 号:T63954产 地:中国大陆
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T62954Ferroportin-IN-1;化合物 Ferroportin-IN-1Ferroportin-IN-1
Ferroportin-IN-1 is an inhibitor of the iron transport protein ferroportin and can be used to study diseases such as thalassaemia, sickle cell disease and haemochromatosis due to iron deficiency or disorders of iron metabolism.
价 格:¥电议型 号:T62954产 地:中国大陆
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T61954HDAC-IN-29;化合物 HDAC-IN-29HDAC-IN-29
HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.
价 格:¥电议型 号:T61954产 地:中国大陆
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T61652WIN 54954;化合物 WIN 54954WIN 54954
WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections.
价 格:¥电议型 号:T61652产 地:中国大陆
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T60954HDAC6-IN-6;化合物 HDAC6-IN-6HDAC6-IN-6
HDAC6-IN-6 (compound 6a) is a potent inhibitor of HDAC6 that can penetrate BBB with an IC50 value of 0.025 μM. HDAC6-IN-6 has potent inhibitory activity against AChE and Aβ 1-42 self-aggregation with IC50 values of 0.72 and 3.0 μM. HDAC6-IN-6 can enhance the outgrowth of neurite without significant neurotoxicity [1].
价 格:¥电议型 号:T60954产 地:中国大陆
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T5954Methyldopa hydrate;L-甲基多巴Alpha-Methyldopa Sesquihydrate|||L-(-)-α-Methyldopa hydrate|||MK-351 hydrat
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, norepinephrine, and epinephrine, and exhibits NO-dependent sedative activity.
价 格:¥电议型 号:T5954产 地:中国大陆
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T4954LSmilagenin;化合物 T4954LPYM50028|||Cogane|||AI3-44895|||PYM 50028;PYM50028|||Cogane|||AI3-44895|||PYM 5
Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson´s disease.
价 格:¥电议型 号:T4954L产 地:中国大陆
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T4954SMILAGENIN ACETATE;乙酰知母皂苷元Nsc15488;Nsc15488|||乙酰知母皂苷元
Smilagenin acetate is a sapogenin derivative that has been shown to upregulate the expression of the acetylcholine M2 receptor in cell assays, making it a candidate for dementia research.
价 格:¥电议型 号:T4954产 地:中国大陆
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T40954Iodobananin;IodobananinIodobananin
Iodobananin effectively inhibits the ATPase activity of the SARS Coronavirus helicase, displaying an IC 50 value of 0.54 μM.
价 格:¥电议型 号:T40954产 地:中国大陆
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T39954AU-15330;化合物AU-15330AU-15330
AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergistically with the AR antagonist enzalutamide.AU-15330 shows partial therapeutic efficacy and non-toxicity with the AR antagonist enzalutamide in a desmoplasia-resistant prostate cancer (CRPC) model. AU-15330 showed partial therapeutic efficacy in a denervation-resistant prostate cancer
价 格:¥电议型 号:T39954产 地:中国大陆
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T39548Amustaline dihydrochloride;Amustaline dihydrochlorideS-303 dihydrochloride;S-303 dihydrochloride
Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key elements: an acridine anchor (a non-covalently bonding intercalator targeting nucleic acids), an effector (a bis-alkylator group that interacts with nucleophiles), and a linker (a flexible carbon chain with a labile ester bond, hydrolyzing at neutral pH to non-reactive products).
价 格:¥电议型 号:T39548产 地:中国大陆
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T39547Naph-EA-malNaph-EA-malThiol-green 1|||Naph-EA-mal
Naph-EA-mal (Thiol-green 1) is a highly efficient and quick-responding thiol fluorescence probe specifically designed for protein labeling and bioimaging applications. This compound offers a rapid detection method and exhibits ultrafast turn-on fluorescence upon interaction with thiols. Naph-EA-mal (Thiol-green 1) enables the detection of thiols in live cells, facilitates the labeling of protein thiols, enables quantification of total thiol concentration in cell lysate, and allows for the determ
价 格:¥电议型 号:T39547产 地:中国大陆
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T39546Fluorescein tyramide;Fluorescein tyramideFluorescein tyramide
Fluorescein tyramide is a widely utilized green fluorescent reagent (λ abs : 494 nm; λ em : 517 nm), primarily employed for tyramide signal amplification (TSA) in low-abundance IHC, ICC, in situ hybridization (FISH), and flow cytometry (FCM) applications.
价 格:¥电议型 号:T39546产 地:中国大陆
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T39545MK-6884;MK-6884MK-6884
MK-6884, a positive allosteric modulator (PAM) of M4 muscarinic receptors, exhibits a high affinity (Ki = 0.19 nM). It is a valuable compound for the investigation of neurodegenerative diseases. Additionally, MK-6884 can be efficiently radiolabeled with carbon-11, enabling its use as a PET imaging agent.
价 格:¥电议型 号:T39545产 地:中国大陆
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T39544IPN60090 dihydrochlorideIPN60090 dihydrochlorideIPN60090 dihydrochloride
IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-60090 dihydrochloride possesses outstanding physicochemical properties and pharmacokinetic characteristics in vivo. Therefore, it is a valuable compound for researching solid tumors, including lung and ovarian cancers.
价 格:¥电议型 号:T39544产 地:中国大陆
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T39543VU6000918;VU6000918VU6000918
VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.
价 格:¥电议型 号:T39543产 地:中国大陆
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T39542PI3Kδ-IN-8PI3Kδ-IN-8PI3Kδ-IN-8
PI3Kδ-IN-8 is a powerful and specific oral inhibitor of PI3Kδ, exhibiting an IC50 of 3.3 nM. It demonstrates preferential inhibition of PI3Kδ when compared to PI3Kα, PI3Kβ, and PI3Kγ, with IC50 values of 377.2 nM, 241.6 nM, and 17.9 nM, respectively. Furthermore, PI3Kδ-IN-8 possesses notable anti-tumor efficacy.
价 格:¥电议型 号:T39542产 地:中国大陆
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T39541THK5351 (R enantiomer);THK5351 (R enantiomer)THK5351 (R enantiomer)
THK5351 R enantiomer is an R enantiomer of THK5351.
价 格:¥电议型 号:T39541产 地:中国大陆