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T79983Flaccidoside II;化合物 Flaccidoside IIFlaccidoside II
Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) cell lines and ameliorates collagen-induced arthritis in mice [1] [2].
价 格:¥电议型 号:T79983产 地:中国大陆
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T79980Flaccidoside III;化合物 Flaccidoside IIIFlaccidoside III
Flaccidoside III, a flavonoid and triterpenoid compound extracted from the aerial parts of N. sativa (Ranunculaceae), demonstrates inhibition of α-Glucosidase (IC50: 256.7 μM) and exhibits potential antioxidant and antidiabetic properties [1].
价 格:¥电议型 号:T79980产 地:中国大陆
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T79718CaMKIIα-PHOTAC;化合物 CaMKIIα-PHOTACCaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα). This molecule facilitates the ubiquitination and subsequent proteasome-mediated degradation of CaMKIIα when exposed to certain light wavelengths. Under illumination, CaMKIIα-PHOTAC diminishes synaptic functions and weakens evoked field excitatory postsynaptic potentials in the mouse hippocampus, thus impacting physiological responses. Additionally, it i
价 格:¥电议型 号:T79718产 地:中国大陆
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T78899Laccase-IN-1;化合物 Laccase-IN-1Laccase-IN-1
Laccase-IN-1 (compound 4b) is an orally active laccase inhibitor, demonstrating an IC50 of 11.3 μM. It exhibits both protective and curative effects against B. dothidea infections in apple fruits. The compound increases cell membrane permeability, disrupts mycelial surface morphology, alters cell ultrastructure, and decreases the ergosterol and exopolysaccharide levels in B. dothidea [1].
价 格:¥电议型 号:T78899产 地:中国大陆
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T7871Calcium D-saccharate tetrahydrate;葡萄糖二酸鈣D-Glucaric acid calcium salt|||Calcium D-saccharate tetrahyd
Calcium D-saccharate tetrahydrate (Calcium D-saccharate tetrahydrate) is an oxidized non-cyclic hexose sugar. It may inhibit carcinogenesis and proliferation of cancer cells.
价 格:¥电议型 号:T7871产 地:中国大陆
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T78101Zymosan A酵母聚糖AZymosan A from Saccharomyces cerevisiae
Zymosan A, derived from Saccharomyces cerevisiae, is a TLR2 agonist and exhibits significant radioprotective effects, mitigating and preventing IR-induced intestinal injury in mice. Furthermore, Zymosan A aids in the regeneration of intestinal stem cells (ISCs) following IR injury [1].
价 格:¥电议型 号:T78101产 地:中国大陆
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T78012CCP peptide TFA;化合物 CCP peptide TFACCP peptide TFA
CCP Peptide TFA, a synthetic cyclic citrullinated peptide, serves as a serological substrate for the detection of anti-CCP antibodies and is a highly specific target for autoantibodies associated with rheumatoid arthritis (RA) [1] [2].
价 格:¥电议型 号:T78012产 地:中国大陆
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T77217Saccharopine hydrochloride;化合物 Saccharopine hydrochlorideSaccharopine hydrochloride
Saccharopine hydrochloride (L-Saccharopine hydrochloride), an intermediate in lysine degradation and a mitochondrial toxin, is produced through the conversion of lysine and α-ketoglutarate by lysine-ketoglutarate reductase. This compound is subsequently oxidized to α-aminoapidate semialdehyde and glutamate by saccharopine dehydrogenase, impairing development by disrupting mitochondrial homeostasis [1] [2] [3].
价 格:¥电议型 号:T77217产 地:中国大陆
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T76390Phosphate acceptor peptide;化合物 Phosphate acceptor peptidePhosphate acceptor peptide
Phosphate acceptor peptide acts as a substrate for cAMP-dependent protein kinase (PKA) and serves as a weak inhibitor of protein kinase C (PKC) [1].
价 格:¥电议型 号:T76390产 地:中国大陆
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T76142Laccase;化合物 LaccaseLaccase
Laccase (Denilite IIS), a multi-copper oxidase (MCO), is prevalent in microorganisms, plants, and fungi. It catalyzes the oxidation of phenolic compounds by removing one electron and facilitates the oxidative coupling of lignin monomers. This process is vital for lignin formation and biodegradation, and laccase may also cross-link food polymers [1].
价 格:¥电议型 号:T76142产 地:中国大陆
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T76072LCCZ01048 TFA;化合物 CCZ01048 TFACCZ01048 TFA
CCZ01048 TFA, an α-MSH analogue, demonstrates a strong binding affinity for the melanocortin 1 receptor (MC1R), displaying a K i value of 0.31 nM. It exhibits rapid internalization into B16F10 melanoma cells and maintains high in vivo stability. CCZ01048 TFA holds potential as an effective agent for PET imaging of malignant melanoma [1].
价 格:¥电议型 号:T76072L产 地:中国大陆
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T75573Taccalonolide E;化合物 Taccalonolide ETaccalonolide E
Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis .
价 格:¥电议型 号:T75573产 地:中国大陆
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T74462SNIPER(TACC3)-11;化合物 SNIPER(TACC3)-11SNIPER(TACC3)-11
SNIPER(TACC3)-11 is a potent degrader of the FGFR3-TACC3 protein, effectively diminishing its levels and inhibiting the proliferation of cancer cells positive for FGFR3-TACC3 [1].
价 格:¥电议型 号:T74462产 地:中国大陆
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T72643Saccharothrixin F;化合物 Saccharothrixin FSaccharothrixin F
Saccharothrixin F, an extensively oxygenated variant within the saccharothrixin class, exhibits antibacterial and anti-inflammatory properties.
价 格:¥电议型 号:T72643产 地:中国大陆
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T72631TACC3 inhibitor 1;化合物 TACC3 inhibitor 1TACC3 inhibitor 1
TACC3 inhibitor 1 is a potent TACC3 inhibitor that can cross the blood-brain barrier, inducing apoptosis and cell cycle arrest at the G2/M phase, as well as the generation of intracellular ROS (reactive oxygen species). It exhibits antiproliferative and anti-tumor activity.
价 格:¥电议型 号:T72631产 地:中国大陆
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T72319Lewis y tetrasaccharide;化合物 Lewis y tetrasaccharideLewis y;Lewis y
Lewis Y Tetrasaccharide (Lewis Y, Le Y) is a tetrasaccharide derivative of Lewis X Trisaccharide, functioning as an antigen linked to the metastasis of malignant ovarian carcinomas and associated with a poor prognosis [1] [2].
价 格:¥电议型 号:T72319产 地:中国大陆
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T7066Fosphenytoin disodium;磷苯妥英钠Fosphenytoin sodium|||ACC-9653;Fosphenytoin sodium|||ACC-9653|||磷苯妥英钠
Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
价 格:¥电议型 号:T7066产 地:中国大陆
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T6974Saccharin 1-methylimidazole;糖精-1-甲基咪唑盐SMI|||Saccharin 1-methylimidazole (SMI);糖精-1-甲基咪唑盐|||SMI|||Sac
Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.
价 格:¥电议型 号:T6974产 地:中国大陆
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T68494Octenidine saccharin;化合物 Octenidine saccharinOctenidine saccharin
Octenidine saccharin is a Dental Plaque Inhibitor
价 格:¥电议型 号:T68494产 地:中国大陆
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T67921Retinoic acid-d5;视黄酸d5all-trans-Retinoic acid-d5|||Isotretinoin-d5|||Vitamin A acid-d5|||Accutane-d5
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2.
价 格:¥电议型 号:T67921产 地:中国大陆