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T10433Osimertinib dimesylate奥希替尼二甲磺酸盐；AZD-9291 (dimesylate)；Mereletinib (dimesylate)
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).
价 格：￥电议型 号：T10433产 地：中国大陆
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T10432LAZD-8529 mesylate
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
价 格：￥电议型 号：T10432L产 地：中国大陆
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T10431GolidocitinibAZD4205
AZD4205 is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).
价 格：￥电议型 号：T10431产 地：中国大陆
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T10429TizaterkibAZD-0364
AZD-0364 is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1 (example 18; IC50: 0.6 nM).
价 格：￥电议型 号：T10429产 地：中国大陆
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T0179TicagrelorAR-C 126532XX；AZD6140；替卡格雷
Ticagrelor, produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European Union by the European Commission on December 3, 2010
价 格：￥电议型 号：T0179产 地：中国大陆
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T0179TicagrelorTicagrelor,AZD6140,AR-C 126532XX
Ticagrelor is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation.
价 格：￥电议型 号：T0179产 地：美洲
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T10429AZD-0364AZD-0364
AZD-0364 is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1 (example 18; IC50: 0.6 nM).
价 格：￥电议型 号：T10429产 地：美洲
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T10430AZD 2066AZD 2066
AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.
价 格：￥电议型 号：T10430产 地：美洲
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T10431AZD4205AZD4205
AZD4205 is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).
价 格：￥电议型 号：T10431产 地：美洲
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T10433Osimertinib dimesylateOsimertinib dimesylate,AZD-9291 (dimesylate),Mereletinib (dimesylate)
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).
价 格：￥电议型 号：T10433产 地：美洲
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T10434AZD-5991AZD-5991
AZD-5991 is a potent and selective Mcl-1 inhibitor (IC50: 0.7 nM in FRET assay; Kd: 0.17 nM in SPR assay).
价 格：￥电议型 号：T10434产 地：美洲
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T10435LinaprazanLinaprazan,AZD0865,
Linaprazan inhibits gastric H+, K+-ATPase by K+-competitive binding (IC50: 1.0 μM). It is an acid-suppressing compound with a rapid onset of action and potent acid inhibition.
价 格：￥电议型 号：T10435产 地：美洲
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T10436AZD4573AZD4573
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格：￥电议型 号：T10436产 地：美洲
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T12658(Rac)-AZD 6482(Rac)-AZD 6482,(Rac)-KIN-193,
(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM).
价 格：￥电议型 号：T12658产 地：美洲
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T12795(S)-Ceralasertib(S)-Ceralasertib,(S)-AZD6738,
(S)-Ceralasertib is a potent and selective inhibitor of sulfoximine morpholinopyrimidine ATR with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. .
价 格：￥电议型 号：T12795产 地：美洲
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T14369AZD-0284AZD-0284
AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].
价 格：￥电议型 号：T14369产 地：美洲
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T14371AZD1152AZD1152,Barasertib,
AZD1152 is a pro-drug of Barasertib-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
价 格：￥电议型 号：T14371产 地：美洲
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T14374AZD2906AZD2906
AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1]. AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats.
价 格：￥电议型 号：T14374产 地：美洲
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T14375AZD3988AZD3988
AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
价 格：￥电议型 号：T14375产 地：美洲
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T14377AZD5423AZD5423
AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM)[1] and it effectively reduces allergen-induced responses in subjects with mild allergic asthma[2].
价 格：￥电议型 号：T14377产 地：美洲
