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T9399Menin-MLL inhibitor 20Epigenetic Reader Domain,mixed-lineage,MeninMLL inhibitor 20,irreversible,leuk
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities (WO2020142557A1, compound 6).
价 格:¥电议型 号:T9399产 地:中国大陆
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T8987Epiblastin Ainduces reprogramming,ATP competitive,epiblast stem cells,inhibit,Casein Kinase,Inhibito
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).
价 格:¥电议型 号:T8987产 地:中国大陆
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T6996SU 5402SU-5402,SU 5402,VEGFR,inhibit,Inhibitor,Fibroblast growth factor receptor,FGFR,Platelet-deriv
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
价 格:¥电议型 号:T6996产 地:中国大陆
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T11063DMT1 blocker 1DMT-1 blocker 1,DMT1 blocker 1
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
价 格:¥电议型 号:T11063产 地:中国大陆
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TP1686LJAG-1, scrambled TFA(402941-23-5 free base)JAG1, scrambled TFA(402941235 free base),JAG 1, scrambled
JAG-1, scrambled TFA is a scrambled sequence of JAG-1(188-204).
价 格:¥电议型 号:TP1686L产 地:中国大陆
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T8333Aurintricarboxylic acidTopoisomerase,Apoptosis,receptor,P2XRs,Influenza Virus,glioblastoma,anti-infl
Aurintricarboxylic acid is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
价 格:¥电议型 号:T8333产 地:中国大陆
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T8657KYP-2047eNOS,inhibit,POP,Neurotensin,Angiopoietins,MDM-2/p53,KYP 2047,prolyl oligopeptidase,Glioblas
KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.
价 格:¥电议型 号:T8657产 地:中国大陆
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T60050ANT3310ANT-3310,ANT3310,inhibit,SBL,infection,CRE,β-lactam antibiotic,ANT 3310,Bacterial,OXA enzymes
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection.
价 格:¥电议型 号:T60050产 地:中国大陆
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T7763Thalidomide-4-OHE3 ligase-recruiting Moiety,inhibit,Inhibitor,Thalidomide4OH,Cereblon ligand2,Ligand
Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs
价 格:¥电议型 号:T7763产 地:中国大陆
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T6S0071FraxinelloneHIFs,Hypoxia-inducible factors,Fraxinellone,HIF-PH,STAT,Inhibitor,inhibit,HIF/HIF Prolyl
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. 3. Fraxinellone has effect in the midgut metabolism of Mythimna separata (M. separata), via protease (especially the weak alkaline trypsin-like enzyme), carboxylesterase and glutathione S-transferase.
价 格:¥电议型 号:T6S0071产 地:中国大陆
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TQ0277PralsetinibInhibitor,BLU 667,BLU-667,Pralsetinib,inhibit,RET
Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion).
价 格:¥电议型 号:TQ0277产 地:中国大陆
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T6911NSC-87877 disodiumApoptosis,Neuroblastoma,inhibit,Inhibitor,NSC 87877 disodium,PPAR,p53,Phosphatase,
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格:¥电议型 号:T6911产 地:中国大陆
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TL0001dencichineHypoxia-inducible factors,HIF/HIF Prolyl-Hydroxylase,dencichine,Inhibitor,HIFs,HIF-PH,inhi
Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effect, it could significantly prevent the progression of diabetic nephropathy possibly attribute to down-regulation of the TGF-β/Smad pathway and rebalance the deposition and degradation of ECM proteins.
价 格:¥电议型 号:TL0001产 地:中国大陆
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T7880IOX4IOX 4,HIF-PH,HIFs,Hypoxia-inducible factors,IOX4,IOX-4,inhibit,HIF/HIF Prolyl-Hydroxylase,Inhibi
IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)
价 格:¥电议型 号:T7880产 地:中国大陆
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T6134IEM 1754 2HBrAMPA receptor,channel block,IEM 1754,Ionotropic glutamate receptors,voltage dependence,
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
价 格:¥电议型 号:T6134产 地:中国大陆
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T6439Cetylpyridinium ChlorideCetylpyridinium,Cetylpyridinium Chloride,HBV,assembly,quaternary,Inhibitor,a
Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
价 格:¥电议型 号:T6439产 地:中国大陆
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T8376PKCβ inhibitor 1PKCβ inhibitor 1,GSK3β,Inhibitor,tumor,PKCβ inhibitor1,proliferation,BCBL-1,mTOR,sel
PKCβ inhibitor 1(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively).
价 格:¥电议型 号:T8376产 地:中国大陆
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T5993ARN-3236inhibit,ARN3236,Salt-inducible Kinase (SIK),ARN-3236,ARN 3236,Inhibitor
ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nM respectively). ARN-3236 Has anti-cancer activity.
价 格:¥电议型 号:T5993产 地:中国大陆
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T8954ML179C57Bl6 mice,inhibit,SAA4,ER-negative breast cancer,probe compounds,ML 179,MCF-7,SAA1,Inhibitor,
ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM.
价 格:¥电议型 号:T8954产 地:中国大陆
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T7861Flumatinib mesylateHHGV-678,PDGFRβ,HHGV678,c-Abl,Bcr-Abl,Platelet-derived growth factor receptor,PDG
Flumatinib mesylate is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.
价 格:¥电议型 号:T7861产 地:中国大陆