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已选条件
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T18640(S,R,S)-AHPC-C4-NH2 hydrochlorideinhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydroch
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格:¥电议型 号:T18640产 地:中国大陆
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T8554KCC-07KCC07,BAI1,p53,inhibit,ADGRB1,anticancer,Inhibitor,DNA Alkylator/Crosslinker,MBD2,KCC-07,anti-
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling.
价 格:¥电议型 号:T8554产 地:中国大陆
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T8494NS-3-008 hydrochloriderenal,inhibit,Ccl2,NS3008 hydrochloride,Hsd17b4,Stat5,transcriptional,Inhibito
NS-3-008 HCl is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).
价 格:¥电议型 号:T8494产 地:中国大陆
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T8482Ripretinibc-Kit,Inhibitor,DCC2618,Vascular endothelial growth factor receptor,CD135,CD117,Platelet-d
Ripretinib is an orally bioavailable inhibitor of KIT and PDGFRA.
价 格:¥电议型 号:T8482产 地:中国大陆
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T9116SMCCSMCC,ADC Linkers,inhibit,Antibody-drug conjugates linkers,Inhibitor
N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC), also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker.
价 格:¥电议型 号:T9116产 地:中国大陆
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T7080CCT245737CCT245737,Inhibitor,CCT 245737,inhibit,Checkpoint Kinase (Chk),CCT-245737
CCT245737 is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).
价 格:¥电议型 号:T7080产 地:中国大陆
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T6S1418Praeruptorin CCa2+ channels,Ca channels,Calcium Channel,Praeruptorin C,Inhibitor,inhibit
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. 3. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kina
价 格:¥电议型 号:T6S1418产 地:中国大陆
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TN2103PROCYANIDIN C1PCC 1,inhibit,Procyanidin C 1,PROCYANIDIN C1,PCC1,PCC-1,PROCYANIDIN C-1,Inhibitor,Apop
Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
价 格:¥电议型 号:TN2103产 地:中国大陆
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TQ0194trans-Vaccenic acidEndogenous Metabolite,Inhibitor,trans-Vaccenic acid,inhibit,trans Vaccenic acid,t
trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid at the tissue level.
价 格:¥电议型 号:TQ0194产 地:中国大陆
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T17325Pomalidomide-PEG4-C-COOHInhibitor,Pomalidomide PEG4 C COOH,PomalidomidePEG4CCOOH,inhibit,E3 Ligase L
Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17325产 地:中国大陆
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T7184FirsocostatND 630,Firsocostat,Acetyl-CoA Carboxylase,NDI 010976,inhibit,NDI010976,ACC, Acetyl Coenzy
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
价 格:¥电议型 号:T7184产 地:中国大陆
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T8381AmodiaquineCCL2,Nurr1,IL-1β,Histone Methyltransferase,Amodiaquine,Amodiaquin,inhibit,Inhibitor,anti-
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
价 格:¥电议型 号:T8381产 地:中国大陆
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T9604beta-Estradiol 17-hemisuccinatebetaEstradiol 17hemisuccinate,beta Estradiol 17 hemisuccinate
beta-Estradiol 17-hemisuccinate selectively stains estrogen receptor (ER)-rich cells.
价 格:¥电议型 号:T9604产 地:中国大陆
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T10639C-021 dihydrochlorideInhibitor,C 021 dihydrochloride,CCL22,CCR4,C021,C021 dihydrochloride,CCR,C 021,
C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.
价 格:¥电议型 号:T10639产 地:中国大陆
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T6474Divalproex SodiumMitophagy,Notch,Apoptosis,Histone deacetylases,Autophagy,hepatic fat accumulation,H
Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC inhibitor. Divalproex Sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex may also work by suppressing r
价 格:¥电议型 号:T6474产 地:中国大陆
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TQ0297CenicrivirocCC chemokine receptor,inhibit,HIV,TBR 652,TAK 652,TBR652,Inhibitor,Human immunodeficienc
Cenicriviroc is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory activity.
价 格:¥电议型 号:TQ0297产 地:中国大陆
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T9783Boc-C16-COOHAntibody-drug conjugates linkers,Boc-C-16-COOH,ADC Linkers,Inhibitor,Boc C16 COOH,BocC16
Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T9783产 地:中国大陆
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T9636DalpiciclibMCF7,BT-474/T,Cyclin dependent kinase,Eca 109,MCF7/TR,and KYSE-510 ESCC,SHR6390,Inhibitor
Dalpiciclib is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4?nM and 9.9?nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
价 格:¥电议型 号:T9636产 地:中国大陆
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TN2256Taccalonolide Binhibit,Taccalonolide B,Microtubule/Tubulin,Inhibitor
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
价 格:¥电议型 号:TN2256产 地:中国大陆
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T962810074-A4Inhibitor,10074-A4,10074-A-4,anticancer,cycle,CDK4,inhibit,cell,c-Myc,10074A4,Myc,CCND2,1007
10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.
价 格:¥电议型 号:T9628产 地:中国大陆