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T7392RevefenacinRevefenacin,TD4208,TD 4208,inhibit,Muscarinic acetylcholine receptor,Inhibitor,mAChR,GSK
Revefenacin is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.
价 格：￥电议型 号：T7392产 地：中国大陆
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T7766RemdesivirDNA/RNA Synthesis,Remdesivir,GS 5734,COVID-19,MERS-CoV,2019-nCoV,antiviral,SARS coronaviru
Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)
价 格：￥电议型 号：T7766产 地：中国大陆
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T7151GSK2982772inhibit,Receptor-interacting protein kinases,GSK2982772,RIPK,Inhibitor,RIP kinase,GSK 2982
GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.
价 格：￥电议型 号：T7151产 地：中国大陆
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T8932GSK046GSK046,Epigenetic Reader Domain,BRDT,BRD2,inhibit,immuno-inflammation,GSK 046,GSK-046,BRD4,Inh
GSK046 is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins(IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively). It has immunomodulatory activity.
价 格：￥电议型 号：T8932产 地：中国大陆
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T8605GS87GS-87,GSK3α,GSK-3,Inhibitor,Glycogen synthase kinase 3,MAPK,GS 87,inhibit,Glycogen synthase kina
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.
价 格：￥电议型 号：T8605产 地：中国大陆
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T27467GSK270822AGSK270822A
GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
价 格：￥电议型 号：T27467产 地：中国大陆
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T6285GSK-690693GSK690693
GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
价 格：￥电议型 号：T6285产 地：中国大陆
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T6282GSK461364GSK461364A
GSK461364(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.
价 格：￥电议型 号：T6282产 地：中国大陆
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T6202DAPTGSI-IX；LY-374973
DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in HEK 293 cells) and Aβ42 levels (IC50: 200 nM).
价 格：￥电议型 号：T6202产 地：中国大陆
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T6198Dolutegravir度鲁特韦；多替拉韦；GSK1349572；S/GSK1349572
Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
价 格：￥电议型 号：T6198产 地：中国大陆
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T6187TDZD-8TDZD8；GSK-3β Inhibitor I；TDZD 8；NP 01139
TDZD-8 is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.
价 格：￥电议型 号：T6187产 地：中国大陆
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T6101EntospletinibGS-9973
Entospletinib （IC50= 7.7 nM）is a specific Syk inhibitor, which is orally bioavailable.
价 格：￥电议型 号：T6101产 地：中国大陆
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T6098Cabotegravir卡博特韦；GSK744；GSK-1265744；S/GSK1265744
Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
价 格：￥电议型 号：T6098产 地：中国大陆
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T6079NVP-ADW742GSK 552602A；ADW；ADW742
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
价 格：￥电议型 号：T6079产 地：中国大陆
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T6076EPZ015666GSK3235025
EPZ015666 is an orally available inhibitor of PRMT5 enzymatic activity.
价 格：￥电议型 号：T6076产 地：中国大陆
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T6059GSK343
GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against other histone methyltransferases.
价 格：￥电议型 号：T6059产 地：中国大陆
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T6054GSK256066
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
价 格：￥电议型 号：T6054产 地：中国大陆
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T6021GSK1324726AI-BET726
GSK1324726A is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).
价 格：￥电议型 号：T6021产 地：中国大陆
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T5857Trametinib (DMSO solvate)Trametinib dimethyl sulfoxide；JTP-74057 (DMSO solvate)；GSK-1120212 (DMSO so
Trametinib DMSO solvate is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)
价 格：￥电议型 号：T5857产 地：中国大陆
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T5745GSK3326595EPZ015938
GSK3326595 is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.).
价 格：￥电议型 号：T5745产 地：中国大陆
