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T6143PI-103PI-103,PI103,PI 103
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).
价 格:¥电议型 号:T6143产 地:美洲
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T6222PFI-1PFI-1,PFI1,PFI 1
PFI-1, a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.
价 格:¥电议型 号:T6222产 地:美洲
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T6484EI1EI1,Ezh2 inhibitor,KB-145943
EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
价 格:¥电议型 号:T6484产 地:美洲
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T8460Olmutinib;化合物OlmutinibHM61713|||BI1482694;HM61713|||BI1482694
Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
价 格:¥电议型 号:T8460产 地:中国大陆
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T8347110-Deacetyl-13-oxobaccatin III;化合物 10-Deacetyl-13-oxobaccatin III10-Deacetyl-13-oxobaccatin III
10-Deacetyl-13-oxobaccatin III, a taxane isolated from Taxus sumatrana, exhibits cytotoxicity at a concentration of 30 μg/mL, inhibiting A498, NCI-H226, A549, and PC-3 cancer cell lines with respective rates of 29.7%, 49.2%, 43.9%, and 65.3% [1].
价 格:¥电议型 号:T83471产 地:中国大陆
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T8343519-Hydroxy-10-deacetylbaccatin III;化合物 19-Hydroxy-10-deacetylbaccatin III19-Hydroxy-10-deacetylbacca
19-Hydroxy-10-deacetylbaccatin III (compound 13), a taxane potentially active against tumors, exhibits low cytotoxicity towards A498 and NCI-H226 cell lines. At a concentration of 30 μg/mL, it inhibits A498 and NCI-H226 cell growth by 16.6% and 32%, respectively [1].
价 格:¥电议型 号:T83435产 地:中国大陆
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T80402Api137;化合物 Api137Api137
Api137 is an antimicrobial peptide that disrupts bacterial growth by blocking translation processes. Specifically, it inhibits protein synthesis through the entrapment of release factors on the 70S ribosome after the hydrolysis of the nascent polypeptide chain [1] [2].
价 格:¥电议型 号:T80402产 地:中国大陆
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T79199F-CRI1;化合物 F-CRI1F-CRI1
F-CRI1, a potent STING agonist with a dissociation constant (K d) of 40.62 nM, is an 18F-labeled radioactive probe employed for visualizing STING in the tumor microenvironment [1].
价 格:¥电议型 号:T79199产 地:中国大陆
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T7545311-epi-Chaetomugilin I;化合物 11-epi-Chaetomugilin I11-epi-Chaetomugilin I
11-epi-Chaetomugilin I, a metabolite identified in Chaetomium globosum, demonstrates notable cytotoxic activity against several cell lines, including the murine P388 and L1210 leukemia cell lines, the human HL-60 leukemia cell line, and the human KB epidermoid carcinoma cell line [1].
价 格:¥电议型 号:T75453产 地:中国大陆
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T74970306Oi10;化合物 306Oi10306Oi10
306Oi10, a branched-chain ionizable lipidoid, facilitates the construction of lipid nanoparticles (LNPs) for messenger RNA delivery [1].
价 格:¥电议型 号:T74970产 地:中国大陆
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T74402FAP-PI3KI1;化合物 FAP-PI3KI1FAP-PI3KI1
FAP-PI3KI1, a fibroblast-activated protein (FAP)-targeted PI3K inhibitor, selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells. It effectively inhibits collagen synthesis and reduces collagen deposition [1].
价 格:¥电议型 号:T74402产 地:中国大陆
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T69866photoGBI1;化合物 photoGBI1photoGBI1
photoGBI1 is a photocontrol inhibitor of the voltage-gated proton channel Hv1.
价 格:¥电议型 号:T69866产 地:中国大陆
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T6941PI-1840;化合物PI1840PI 1840;PI 1840
PI-1840(IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
价 格:¥电议型 号:T6941产 地:中国大陆
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T6889MI-136;化合物MI136MI-136
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.
价 格:¥电议型 号:T6889产 地:中国大陆
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T67930LCWI1-2 HCL;CWI1-2盐酸盐CWI1-2 HCL
CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukemia.
价 格:¥电议型 号:T67930L产 地:中国大陆
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T67930CWI1-2;化合物CWI1-2CWI1-2
CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2. CWI1-2 has anti-leukemic activity and can induce apoptosis and differentiation.
价 格:¥电议型 号:T67930产 地:中国大陆
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T6691TAI-1;化合物TAI1TAI-1
TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.
价 格:¥电议型 号:T6691产 地:中国大陆
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T6484EI1;化合物EI1KB-145943|||Ezh2 inhibitor;KB-145943|||Ezh2 inhibitor
EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
价 格:¥电议型 号:T6484产 地:中国大陆
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T6347Ki16198;化合物Ki16198Ki16198
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.
价 格:¥电议型 号:T6347产 地:中国大陆
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T62692ML-SI1;化合物 ML-SI1ML-SI1
ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).
价 格:¥电议型 号:T62692产 地:中国大陆