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T40941Olmesartan lactone impurity;Olmesartan lactone impurityOlmesartan lactone impurity
Olmesartan lactone impurity is a cyclic ester impurity derived from Olmesartan, which is an angiotensin II receptor (AT1R) antagonist with potential applications in the study of high blood pressure.
价 格:¥电议型 号:T40941产 地:中国大陆
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T40785Gefitinib impurity 1;Gefitinib impurity 1Gefitinib impurity 1
Gefitinib impurity 1 is a compound derived from Gefitinib, a potent and selective EGFR tyrosine kinase inhibitor (IC 50 = 33 nM). This orally active compound selectively inhibits tumor cell growth stimulated by EGF (IC 50 = 54 nM) and inhibits EGFR autophosphorylation induced by EGF in tumor cells. Additionally, Gefitinib induces autophagy and exhibits antitumor activity.
价 格:¥电议型 号:T40785产 地:中国大陆
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T40752Ibuprofen Impurity F;Ibuprofen Impurity FIbuprofen Impurity F
Ibuprofen Impurity F is a known impurity of Ibuprofen, which acts as an anti-inflammatory inhibitor that selectively targets both COX-1 and COX-2 enzymes. It exhibits inhibitory activity with IC50 values of 13 μM and 370 μM for COX-1 and COX-2, respectively.
价 格:¥电议型 号:T40752产 地:中国大陆
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T40537Ibuprofen Impurity K;Ibuprofen Impurity KIbuprofen Impurity K
Ibuprofen Impurity K is a compound that serves as an impurity in Ibuprofen. Ibuprofen itself is an anti-inflammatory inhibitor specifically designed to target COX-1 and COX-2. It exhibits inhibitory activity with IC50 values of 13 μM and 370 μM for COX-1 and COX-2, respectively.
价 格:¥电议型 号:T40537产 地:中国大陆
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T40430Cetirizine Impurity D;西替利嗪杂质DCetirizine Impurity D
Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine is a second-generation antihistamine that acts as a specific, orally active, and long-acting antagonist of the histamine H1-receptor. Cetirizine exhibits antiallergic properties and inhibits eosinophil chemotaxis in response to allergies.
价 格:¥电议型 号:T40430产 地:中国大陆
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T39885Captopril EP Impurity E;Captopril EP Impurity ECaptopril EP Impurity E
Captopril EP Impurity E is an impurity of Captopril. Captopril, also known as SQ-14534, is an orally active angiotensin-converting enzyme (ACE) inhibitor that contains a thiol group. It has antihypertensive properties and competes with ACE with an inhibitor constant (IC 50 ) of 0.025 μM.
价 格:¥电议型 号:T39885产 地:中国大陆
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T39031Olmesartan impurity;Olmesartan impurityOlmesartan impurity
Olmesartan impurity, a compound related to Olmesartan, is an angiotensin II receptor (AT1R) antagonist utilized in the study of high blood pressure. Olmesartan (RNH-6270) is the parent compound with similar properties and functions as an AT1R antagonist.
价 格:¥电议型 号:T39031产 地:中国大陆
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T38740Rivastigmine carbamate impurity利凡斯的明氨基甲酸酯杂质;利瓦斯的明氨基甲酸酯杂质;卡巴拉汀氨基甲酸酯杂质;利斯的明氨基甲酸酯杂质利凡斯的明氨基甲酸酯杂质;利瓦斯的明氨基
Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is a byproduct found in Rivastigmine, which is recognized as a powerful and orally active inhibitor of cholinesterase (ChE). Specifically, Rivastigmine effectively inhibits both butyrylcholinesterase (BChE) and acetylcholinesterase (AChE), with IC50 values of 0.037 μM and 4.15 μM, respectively.
价 格:¥电议型 号:T38740产 地:中国大陆
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T38577Remdesivir O-desphosphate acetonide impurity;Remdesivir O-desphosphate acetonide impurityRemdesivir
Remdesivir O-desphosphate acetonide impurity is a contaminant found in Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue known for its potent antiviral properties, particularly in inhibiting SARS-CoV-2 (COVID-19) infection in vitro.
价 格:¥电议型 号:T38577产 地:中国大陆
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T37817Terazosin dimer impurity dihydrochloride;双盐酸特拉唑嗪杂质Terazosin dimer impurity dihydrochloride
Terazosin dimer impurity dihydrochloride, a dimeric form of Terazosin, is a chemical impurity found in Terazosin. Terazosin itself is a derivative of quinazoline and acts as a competitive and orally active α1-adrenoceptor antagonist[1].
价 格:¥电议型 号:T37817产 地:中国大陆
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T37704Olanzapine Lactam Impurity;Olanzapine Lactam ImpurityOlanzapine Lactam Impurity
Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress.
价 格:¥电议型 号:T37704产 地:中国大陆
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T37628Ibuprofen impurity 1;Ibuprofen impurity 1Ibuprofen impurity 1
Ibuprofen impurity 1 is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].
价 格:¥电议型 号:T37628产 地:中国大陆
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T37176Edoxaban impurity 6;Edoxaban impurity 6Edoxaban impurity 6
Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2].
价 格:¥电议型 号:T37176产 地:中国大陆
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T37175Edoxaban impurity 4;Edoxaban impurity 4Edoxaban impurity 4
Edoxaban impurity 4, an impurity of Edoxaban (DU-176), is a selective, potent, and orally active inhibitor of factor Xa (FXa), exhibiting Kis of 0.561 nM for free FXa and 2.98 nM for prothrombinase. As an anticoagulant agent, Edoxaban is utilized for stroke prevention[1][2].
价 格:¥电议型 号:T37175产 地:中国大陆
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T37026Mesalamine impurity P;Mesalamine impurity PMesalamine impurity P
Mesalamine impurity P is an impurity of Mesalamine . 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1].
价 格:¥电议型 号:T37026产 地:中国大陆
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T36945Cetirizine Impurity C;Cetirizine Impurity CCetirizine Impurity C
Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine is a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. It acts as a specific, orally active, and long-acting antagonist of the histamine H1-receptor[1][2].
价 格:¥电议型 号:T36945产 地:中国大陆
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T36592Impurity of Calcipotriol;Impurity of CalcipotriolImpurity of Calcipotriol
Impurity of Calcipotriol is an impurity in calcipotriol, a synthetic VitD3 analog.
价 格:¥电议型 号:T36592产 地:中国大陆
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T36076Ciprofibrate impurity A;Ciprofibrate impurity ACiprofibrate impurity A
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1].
价 格:¥电议型 号:T36076产 地:中国大陆
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T36006Olmesartan medoxomil impurity C;Olmesartan medoxomil impurity COlmesartan medoxomil impurity C
Olmesartan medoxomil impurity C is an impurity of Olmesartan medoxomil, a potent and selective angiotensin AT1 receptor inhibitor with an IC50 of 66.2 μM.
价 格:¥电议型 号:T36006产 地:中国大陆
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T35876Chlorthalidone Impurity G;Chlorthalidone Impurity GChlorthalidone Impurity G
Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotransporter in the distal convoluted tubule of the kidney, which prevents reabsorption of sodium and chloride leading to a reduction in plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including the isoforms CAVB, VII, IX, XII, and XIII (Kis = 2.8-23 nM) an
价 格:¥电议型 号:T35876产 地:中国大陆